Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Qing Kang-Fortner"'
Autor:
Stéphane de Botton, Thomas Cluzeau, Carlos Vigil, Rachel J. Cook, Philippe Rousselot, David A. Rizzieri, Jane L. Liesveld, Pierre Fenaux, Thorsten Braun, Anne Banos, Joseph G. Jurcic, Mikkael A. Sekeres, Michael R. Savona, Gail J. Roboz, Dale Bixby, Kate Madigan, Angela Volkert, Kristin Stephens, Qing Kang-Fortner, Kristen Baker, Sofia Paul, Michael McKeown, John Carulli, Matthew Eaton, Graeme Hodgson, Christopher Fiore, Michael J. Kelly, David A. Roth, Eytan M. Stein
Publikováno v:
Blood Advances. 7:1858-1870
A superenhancer at the retinoic acid receptor alpha (RARA) gene is associated with RARA mRNA overexpression in ∼30% of non-acute promyelocytic leukemia acute myeloid leukemia (AML) and in ∼50% of myelodysplastic syndromes (MDS). RARA overexpressi
Autor:
Amy DeZern, Pierre Fenaux, Dries Deeren, Maria Diez Campelo, Michael Lübbert, Pramila Krishnamurthy, Zsolt Nagy, Grzegorz Basak, Anna Jonáš ová, Klaus Geissler, Yishai Ofran, Angela Volkert, Kristen Baker, Jaime Chisholm, Qing Kang-Fortner, David A. Roth, Michael Kelly, Giovanni Marconi
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S303-S304
Autor:
Amy DeZern, Pierre Fenaux, Dries Deeren, Maria Diez Campelo, Michael Lübbert, Pramila Krishnamurthy, Zsolt Nagy, Grzegorz Basak, Anna Jonáš ová, Klaus Geissler, Yishai Ofran, Angela Volkert, Kristen Baker, Jaime Chisholm, Qing Kang-Fortner, David A. Roth, Michael Kelly, Giovanni Marconi
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S150
Autor:
Amy Elizabeth Dezern, Giovanni Marconi, Dries Deeren, Maria Diez Campelo, Michael Lübbert, Pramila Krishnamurthy, Zsolt Nagy, Grzegorz Basak, Elena Morozova, Klaus Geissler, Yishai Ofran, Heather Kelley, Angela Volkert, Kristen Baker, Qing Kang-Fortner, Catherine Madigan, David A. Roth, Michael Kelly, Pierre Fenaux
Publikováno v:
Journal of Clinical Oncology. 40:TPS7075-TPS7075
TPS7075 Background: A novel genomically defined subset of higher-risk MDS (HR-MDS) patients with an actionable target characterized by overexpression of RARA has been identified (McKeown 2017). Approximately 30% of HR-MDS patients are RARA-positive (
Autor:
Eytan Stein, Stéphane De Botton, Arnaud Pigneux, Christine McMahon, Brian Ball, Gautam Borthakur, Alireza Eghtedar, Suman Kambhampati, Jason Tache, Eunice S. Wang, Heather Kelley, Angela Volkert, Kristen Baker, Qing Kang-Fortner, Catherine Madigan, Erica D. Warlick, David A. Roth, Michael Kelly, Daniel Aaron Pollyea
Publikováno v:
Journal of Clinical Oncology. 40:TPS7065-TPS7065
TPS7065 Background: RARA-positive (RARA+) AML is a novel genomically defined patient subset with an actionable biological target for treatment with tamibarotene, an oral and selective RARα agonist (McKeown 2017). RARA+ patients can be selected by a
Autor:
Philippe Rousselot, Michael R. Savona, Qing Kang-Fortner, Don Park, Li Zhou, David A. Rizzieri, Carlos E. Vigil, Pierre Fenaux, Eytan M. Stein, David A. Roth, Thomas Cluzeau, Anne Banos, Angela Volkert, Rachel J. Cook, Michael J. Kelly, Thorsten Braun, Jane L. Liesveld, Stéphane de Botton
Publikováno v:
Blood. 136:4-5
Introduction: A novel genomically defined subset of non-APL AML patients (pts) with an actionable target characterized by overexpression of RARA has been identified (McKeown, Cancer Discovery 2017). RARA-positive (RARA+) pts can be detected by a nove
Autor:
Li Zhou, Matthew L. Eaton, Kate Madigan, Qing Kang-Fortner, Graeme Hodgson, Michael Kelly, Angela Volkert, David A. Roth, Christopher Fiore
Publikováno v:
Blood. 136:15-16
Introduction: Super-enhancer (SE) mapping in non-APL AML patient (pt) blasts identified RARα as a novel therapeutic target in approximately 30% of pts, who have elevated RARA gene expression. It was observed that the enhancer profile of this novel p
Autor:
Delphine Lebon, Qing Kang-Fortner, Gail J. Roboz, Stéphane de Botton, David A. Rizzieri, Philippe Rousselot, Thorsten Braun, Pierre Peterlin, Eytan M. Stein, Maël Heiblig, David A. Roth, Jane L. Liesveld, Michael J. Kelly, Thomas Cluzeau, Li Zhou, Arnaud Pigneux, Dale L. Bixby, Angela Volkert, Rachel J. Cook
Publikováno v:
Blood. 136:6-7
Introduction: RARA-positive (RARA+) AML patients represent a subset of non-APL AML characterized by high RARA expression levels, which can be identified by a novel blood-based biomarker test that predicts sensitivity to SY-1425, an oral selective RAR
Autor:
Kyriakos P. Papadopoulos, Catherine Madigan, Graeme Hodgson, David A. Roth, Li Zhou, Nan Ke, Debra L. Richardson, Qing Kang-Fortner, Erika Hamilton, William C. Zamboni, Babar Bashir, Hina A. Jolin, Michael J. Kelly, Manish R. Sharma
Publikováno v:
European Journal of Cancer. 138:S50