Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Qing K, Wang"'
Autor:
He Yang, Lei Sun, Xuemei Bai, Bingcheng Cai, Zepeng Tu, Chen Fang, Yusheng Bian, Xiaoyu Zhang, Xudong Han, Dayin Lv, Chi Zhang, Bo Li, Shaoxiang Luo, Bingbing Du, Lan Li, Yufeng Yao, Zhiqiang Dong, Zhuowei Huang, Guanhua Su, Hui Li, Qing K. Wang, Min Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Psychological stress contributes to cardiovascular disease (CVD) and sudden cardiac death, yet its molecular basis remains obscure. RNA binding protein RBM24 plays a critical role in cardiac development, rhythm regulation, and cellular stres
Externí odkaz:
https://doaj.org/article/a1c41a7c1b344ffda816def7275b5e2b
Autor:
Xingwen Da, Ziyan Li, Xiaofan Huang, Zuhan He, Yubing Yu, Tongtong Tian, Chengqi Xu, Yufeng Yao, Qing K. Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Thoracic aortic aneurysm (TAA) is a localized or diffuse dilatation of the thoracic aortas, and causes many sudden deaths each year worldwide. However, there is no effective pharmacologic therapy. Here, we show that AGGF1 effectively blocks
Externí odkaz:
https://doaj.org/article/3120fd133c2c4af8a1131ffee437cb60
Autor:
Zuhan He, Qixue Song, Yubing Yu, Feng Liu, Jinyan Zhao, Waikeong Un, Xingwen Da, Chengqi Xu, Yufeng Yao, Qing K. Wang
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 978-991 (2023)
Abstract Background Skeletal muscle atrophy is a common condition without a pharmacologic therapy. AGGF1 encodes an angiogenic factor that regulates cell differentiation, proliferation, migration, apoptosis, autophagy and endoplasmic reticulum stress
Externí odkaz:
https://doaj.org/article/4d5bbdaeb61846d290937cbb0cf64a8f
Autor:
Jianwen Chen, Ruirui He, Wanwei Sun, Ru Gao, Qianwen Peng, Liwen Zhu, Yanyun Du, Xiaojian Ma, Xiaoli Guo, Huazhi Zhang, Chengcheng Tan, Junhan Wang, Wei Zhang, Xiufang Weng, Jianghong Man, Hermann Bauer, Qing K. Wang, Bradley N. Martin, Cun-Jin Zhang, Xiaoxia Li, Chenhui Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
TAGAP gene variants are linked to human autoimmunity. Here the authors identify TAGAP as a Dectin-1 and EphB2-binding protein mediating antifungal innate immune signaling and cytokine production, and demonstrate TAGAP in non-T cells promotes Th17 res
Externí odkaz:
https://doaj.org/article/69258493889b41e28feb66c907a43116
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Endoplasmic reticulum (ER) stress promotes cardiac dysfunction. Here the authors uncover a pathway whereby AGGF1 blocks ER stress by inhibiting ERK1/2 activation and the transcriptional repressor ZEB1, leading to induction of miR-183-5p and down-regu
Externí odkaz:
https://doaj.org/article/6125403f9aea40e3becc9eae807175b5
Autor:
Yang Guo, Fan Wang, Lin Li, Hanxiang Gao, Stephen Arckacki, Isabel Z. Wang, John Barnard, Stephen Ellis, Carlos Hubbard, Eric J. Topol, Qiuyun Chen, Qing K. Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Coronary artery disease (CAD) is the leading cause of death, and genetic factors contribute significantly to risk of CAD. This study aims to identify new CAD genetic loci through a large-scale linkage analysis of 24 large and multigeneration
Externí odkaz:
https://doaj.org/article/19d7af9badc641428546028580f0c1f1
Autor:
Yan Yao, Chenxi Jiang, Fan Wang, Han Yan, Deyong Long, Jinghua Zhao, Jiangang Wang, Chunxiao Zhang, Yang Li, Xiaoli Tian, Qing K. Wang, Gang Wu, Zhihui Zhang
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
BackgroundLimited findings have been reported to systematically study miRNA and mRNA expression profiles in aged human atria. In this study, we aimed to identify miRNAs, genes, and miRNA-mRNA interaction networks for human atrial aging (AA).MethodsRi
Externí odkaz:
https://doaj.org/article/82e0dbfd32764d7aace8c788e65b7f8f
Autor:
Xiaoyu Zhang, Qianqian Liu, Hongfu Zhang, Chengcheng Tan, Qiangfeng Zhu, Saiyong Chen, Yinglong Du, Haitao Yang, Qingli Li, Chengqi Xu, Chun Wu, Qing K. Wang
Publikováno v:
Molecular Genetics and Genomics. 297:833-841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfaff1f15e68a316d267126c9dc277c3
https://doi.org/10.1007/s00438-022-01892-4
https://doi.org/10.1007/s00438-022-01892-4
Autor:
Zhongcheng Yang, Di Guo, Jinyan Zhao, Jia Li, Rui Zhang, Yidan Zhang, Chengqi Xu, Tie Ke, Qing K. Wang
Publikováno v:
Arteriosclerosis, Thrombosis & Vascular Biology; Nov2023, Vol. 43 Issue 11, p2348-2368, 21p
Autor:
Shao-Fang Nie, Ling-Feng Zha, Qian Fan, Yu-Hua Liao, Hong-Song Zhang, Qian-Wen Chen, Fan Wang, Ting-Ting Tang, Ni Xia, Cheng-Qi Xu, Jiao-Yue Zhang, Yu-Zhi Lu, Zhi-Peng Zeng, Jiao Jiao, Yuan-Yuan Li, Tian Xie, Wen-Juan Zhang, Dan Wang, Chu-Chu Wang, Jing-Jing Fa, Hong-Bo Xiong, Jian Ye, Qing Yang, Peng-Yun Wang, Sheng-Hua Tian, Qiu-Lun Lv, Qing-Xian Li, Jin Qian, Bin Li, Gang Wu, Yan-Xia Wu, Yan Yang, Xiang-Ping Yang, Yu Hu, Qing K. Wang, Xiang Cheng, Xin Tu
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The thymic stromal lymphopoietin (TSLP)/TSLP receptor (TSLPR) axis is involved in multiple inflammatory immune diseases, including coronary artery disease (CAD). To explore the causal relationship between this axis and CAD, we performed a three-stage
Externí odkaz:
https://doaj.org/article/8d1e3628835b4010b3c9f913f4606af7