Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Qing J. Cao"'
Autor:
Barbara A. Osborne, Ellen S. Dickinson, Richard B. Arenas, Elizabeth A. Xavier, D. Joseph Jerry, Rebecca G. Lawlor, Frances S. Kittrell, Qing J. Cao, Jae Hong Seo, Daniel Medina, Haoheng Yan, S. Christine McLary, Christopher N. Otis, Amy L. Roberts, Anneke C. Blackburn, Luwei Tao
Publikováno v:
The American Journal of Pathology. 176:1421-1432
Mutation and loss of function in p53 are common features among human breast cancers. Here we use BALB/c-Trp53+/- mice as a model to examine the sequence of events leading to mammary tumors. Mammary gland proliferation rates were similar in both BALB/
Autor:
Stephen P. Naber, Tania Nikolcheva, Gary Peltz, Annemarie Poustka, Christopher N. Otis, Amy L. Roberts, Reva St. J. Ricketts, Jimmy Jung, Linda Zhai Hill, John Allard, Jun Wang, Qing J. Cao, Jan Mollenhauer, Dee Aud, Daniel Malamud, D. Joseph Jerry, Anneke C. Blackburn
Publikováno v:
The American journal of pathology. 170(6)
Low-penetrance breast cancer susceptibility alleles seem to play a significant role in breast cancer risk but are difficult to identify in human cohorts. A genetic screen of 176 N2 backcross progeny of two Trp53(+/-) strains, BALB/c and C57BL/6, whic