Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Qing Bing Zha"'
Autor:
Fu-li Shi, Li-sha Yuan, Tak-sui Wong, Qing Li, Ya-ping Li, Rong Xu, Yi-ping You, Tao Yuan, Hong-rui zhang, Zi-jian Shi, Qing-bing Zha, Bo Hu, Xian-hui He, Dong-yun Ouyang
Publikováno v:
Pharmacological Research, Vol 189, Iss , Pp 106697- (2023)
Necroptosis has been implicated in various inflammatory diseases including tumor-necrosis factor-α (TNF-α)-induced systemic inflammatory response syndrome (SIRS). Dimethyl fumarate (DMF), a first-line drug for treating relapsing-remitting multiple
Externí odkaz:
https://doaj.org/article/ce3aec9a4834464ab895dd0a7a4df808
Publikováno v:
Rare Metals. 42:1274-1282
Autor:
Qiong-zhen Zeng, Fan Yang, Chen-guang Li, Li-hui Xu, Xian-hui He, Feng-yi Mai, Chen-ying Zeng, Cheng-cheng Zhang, Qing-bing Zha, Dong-yun Ouyang
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Microtubules play critical roles in regulating the activation of NLRP3 inflammasome and microtubule-destabilizing agents such as colchicine have been shown to suppress the activation of this inflammasome. However, it remains largely unknown whether p
Externí odkaz:
https://doaj.org/article/8425970e898e49b59618fa83a794b514
Autor:
Si-yuan Chen, Ya-ping Li, Yi-ping You, Hong-rui Zhang, Zi-jian Shi, Qi-qi Liang, Tao Yuan, Rong Xu, Li-hui Xu, Qing-bing Zha, Dong-yun Ou-Yang, Xian-hui He
Publikováno v:
Acta Pharmacologica Sinica.
Autor:
Yi Liu, Yan-Yun Jing, Chen-Ying Zeng, Chen-Guang Li, Li-Hui Xu, Liang Yan, Wen-Jing Bai, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2018)
The NLRP3 inflammasome plays a critical role in mediating the innate immune defense against pathogenic infections, but aberrant activation of NLRP3 inflammasome has been linked to a variety of inflammatory diseases. Thus targeting the NLRP3 inflammas
Externí odkaz:
https://doaj.org/article/b6c8d637d5934511862813747960e184
Autor:
Chen-Guang Li, Liang Yan, Feng-Yi Mai, Zi-Jian Shi, Li-Hui Xu, Yan-Yun Jing, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The flavonoid baicalin has been reported to possess potent anti-inflammatory activities by suppressing inflammatory signaling pathways. However, whether baicalin can suppress the activation of NOD-like receptor (NLR) family, pyrin containing domain 3
Externí odkaz:
https://doaj.org/article/60744548f2904122851476da0201aa05
Autor:
Qing-Bing Zha, Hong-Xia Wei, Chen-Guang Li, Yi-Dan Liang, Li-Hui Xu, Wen-Jing Bai, Hao Pan, Xian-Hui He, Dong-Yun Ouyang
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
ATP is released by bacteria and host cells during bacterial infection as well as sterile tissue injury, acting as an inducer of inflammasome activation. Previous studies have shown that ATP treatment leads to AMP-activated protein kinase (AMPK) activ
Externí odkaz:
https://doaj.org/article/ac33fa8d8033494190b190b6d63d20a2
Autor:
Qi-Qi Liang, Zi-Jian Shi, Tao Yuan, Si-Yuan Chen, Ya-Ping Li, Hong-Rui Zhang, Yi-Ping You, Rong Xu, Li-Hui Xu, Bo Hu, Dong-Yun Ouyang, Qing-Bing Zha, Xian-Hui He
Publikováno v:
International Immunopharmacology. 117:109974
Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
Autor:
Qing-Bing Zha, Xiao-Yu Zhang, Qiu-Ru Lin, Li-Hui Xu, Gao-Xiang Zhao, Hao Pan, Dan Zhou, Dong-Yun Ouyang, Ze-Huan Liu, Xian-Hui He
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124355 (2015)
Cucurbitacins, the natural triterpenoids possessing many biological activities, have been reported to suppress the mTORC1/p70S6K pathway and to induce autophagy. However, the correlation between such activities is largely unknown. In this study, we a
Externí odkaz:
https://doaj.org/article/5b5a4fe2eade4246a116773957acd870
Autor:
Xian-Hui He, Ming-ye Chen, Li-Hui Xu, Fu-li Shi, Xun-jia Ye, Zi-Jian Shi, Si-ying Liu, Dong-Yun Ouyang, Rong Xu, Bo Hu, Qing-Bing Zha, Bo Zeng, Yuan-ting Huang
Publikováno v:
International immunopharmacology. 102
Discovery of anti-inflammatory drugs that can suppress T lymphocyte activation and proliferation by inhibiting TCR/CD3 and IL-2/IL-2R signaling is still needed in clinic, though rapamycin and other related reagents have made great success. Taraxaster