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pro vyhledávání: '"Qinchao Cai"'
Autor:
Brandon G. Howell, Qinchao Cai, Claudio Feliciani, Binghe Wang, Hideaki Watanabe, Irwin Freed, Daniel N. Sauder
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 168(7)
The epidermal Langerhans cells (LC), a member of the dendritic cell family, and the LC-derived cytokine IL-12 play a pivotal role in the initiation of contact hypersensitivity (CHS), a Th1 immune response in the skin. Because IL-18, another LC-derive
Publikováno v:
Journal of leukocyte biology. 70(2)
Contact hypersensitivity (CHS), a dendritic-cell (DC)-dependent, T-cell-mediated skin immune response to reactive haptens, has been a subject of intense research for many years. The molecular mechanisms underlying CHS are complicated and are not full