Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Qin Zhi Gong"'
Autor:
Michael M. Folkerts, Candace L. Floyd, J. Paul Muizelaar, Bruce G. Lyeth, Lillian L. Lee, Qin-Zhi Gong, Thomas M. Hallam, Robert F. Berman
Publikováno v:
Journal of Neurotrauma. 21:521-539
The behavioral and histological effects of the lateral fluid percussion (LFP) brain injury model were compared with the weight drop impact-acceleration model with 10 min of secondary hypoxia (WDIA + H). LFP injury resulted in significant motor defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1178aa3fee2364c73f08c4124e3ef805
https://doi.org/10.1089/089771504774129865
https://doi.org/10.1089/089771504774129865
Publikováno v:
Journal of Neurotrauma. 16:1095-1102
Various methods of continuous intracranial pressure (ICP) monitoring during experimental procedures in the rat have been described. However, no systematic comparison of ICP monitoring in the ventricle, brain parenchyma, and cisterna magna has been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7084de06b4b3255a9cf655b0f91f771
https://doi.org/10.1089/neu.1999.16.1095
https://doi.org/10.1089/neu.1999.16.1095
Publikováno v:
Journal of Neurotrauma. 16:893-902
Glutamate toxicity, mediated via ion channel-linked receptors, plays a key role in traumatic brain injury (TBI) pathophysiology. Excessive glutamate release after TBI also activates protein G-linked metabotropic glutamate receptors (mGluRs). We perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daff0ac0fb7f75ce52ddc52e90b4a558
https://doi.org/10.1089/neu.1999.16.893
https://doi.org/10.1089/neu.1999.16.893
Publikováno v:
Molecular and Chemical Neuropathology. 30:125-137
We examined the effects of N omega-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide synthase (NOS), on mortality, morbidity, and cardiovascular parameters following traumatic brain injury (TBI) in the rat. Rats were anesthetized w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6b1b1d6e692dfd86158ba85c313c83
https://doi.org/10.1007/bf02815154
https://doi.org/10.1007/bf02815154
Autor:
Robert J. DeLorenzo, Melissa D. Shumate, Bruce G. Lyeth, Azhar Rafiq, Douglas A. Coulter, Qin Zhi Gong
Publikováno v:
Epilepsy Research. 26:81-91
Traumatic brain injury (TBI) is a leading cause of symptomatic epilepsy in young adults. This study examined physiological and anatomical epileptogenic consequences of a prior incident of TBI in rats. Rats were subjected to a fluid percussion brain i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9f83e2d1a1a96f5623982ce9d161a7
https://doi.org/10.1016/s0920-1211(96)00044-7
https://doi.org/10.1016/s0920-1211(96)00044-7
Publikováno v:
Brain Research. 742:63-70
Hippocampal levels of fatty acids extracted from phosphatidylinositol 4,5-bisphosphate (PIP2), free fatty acids (FFA), and lactate were measured after central fluid percussion traumatic brain injury (TBI) in rats. At 5 min after injury, there was a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a09c64085d1730a44449b0b45910e9
https://doi.org/10.1016/s0006-8993(96)01002-5
https://doi.org/10.1016/s0006-8993(96)01002-5
Publikováno v:
Brain Research. 700:299-302
The metabotropic glutamate receptor (mGluR) antagonist, alpha-methyl-4-carboxyphenylglycine (MCPG) was administered into the left lateral ventricle 5 min prior to fluid percussion traumatic brain injury (TBI) in the rat. A single 5.0 microliters vent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb105151519c3fb1b895eac64e82b9b3
https://doi.org/10.1016/0006-8993(95)01081-6
https://doi.org/10.1016/0006-8993(95)01081-6
Publikováno v:
Neurosurgery. 48(5)
OBJECTIVE The role of metabotropic glutamate receptor activation after traumatic brain injury (TBI) is not well understood. In vitro studies suggest that activation of Groups II and III metabotropic glutamate receptors may provide some degree of neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b399b168d00533c7cfc4e1d98a21db7
https://pubmed.ncbi.nlm.nih.gov/11334279
https://pubmed.ncbi.nlm.nih.gov/11334279
Publikováno v:
Experimental neurology. 169(1)
Recent studies indicate that acute activation of Group I mGluRs following traumatic brain injury (TBI) contributes to the ensuing pathophysiology. The present study examined the effects of post-TBI administration of the selective mGluR1 antagonist (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035249df844f3eac2018d4514169ead8
https://pubmed.ncbi.nlm.nih.gov/11312571
https://pubmed.ncbi.nlm.nih.gov/11312571
Publikováno v:
Brain research. 852(1)
The rat subdural hematoma (SDH) model produces a zone of ischemic brain damage within the hemisphere beneath the SDH. Previous studies have measured large increases in extracellular acetylcholine during cerebral ischemia in the rat. We examined infar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba349e81c0d7a0524806db832a157eb7
https://pubmed.ncbi.nlm.nih.gov/10661493
https://pubmed.ncbi.nlm.nih.gov/10661493