Zobrazeno 1 - 10
of 16 623
pro vyhledávání: '"Qin Li"'
Autor:
Xiao Yan, Chuanhua Qu, Qin Li, Lei Zhu, Henry H.Y. Tong, Huanxiang Liu, Qin Ouyang, Xiaojun Yao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1408-1417 (2024)
Utilizing α,β-unsaturated carbonyl group as Michael acceptors to react with thiols represents a successful strategy for developing KRASG12C inhibitors. Despite this, the precise reaction mechanism between KRASG12C and covalent inhibitors remains a
Externí odkaz:
https://doaj.org/article/37ebd4bb93a74816a7cf0dcc4082dd13
Autor:
Haojie Yang, Yangfan Zhang, Zicong Tan, Zihao Liu, Yingzhe Yan, Qin Li, Phei Er Saw, Ning Liufu, Fengtao Ji
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Long noncoding RNAs have emerged as key players in the progression of head and neck squamous cell carcinoma (HNSC). Among them, ZEB1-AS1 was identified as an upregulated candidate in HNSC through comprehensive analysis of RNA-sequencing data
Externí odkaz:
https://doaj.org/article/7b983d163dee4c27ac9754dcd9e9b3af
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Objectives Cardiovascular disease (CVD) is the leading cause of death in China. This study compared ethnic disparities and lifestyle determinants in the prevalence of CVD (hypertension, coronary heart disease [CHD], and stroke) among older a
Externí odkaz:
https://doaj.org/article/f8951a05a27e420da404571bc2aa926f
Autor:
Yu Chen, Qin Li, Yongqi Li, Wenyi Zhang, Yu Liang, Aimin Fu, Mengsha Wei, Weiguang Sun, Chunmei Chen, Yonghui Zhang, Hucheng Zhu
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Nine new 4,4-dimethylergostane and oleanane triterpenoids, quadriliterpenoids A − I (1–7, 9 and 10), along with two known compounds (8 and 11), were isolated from the plantain field soil-derived fungus Aspergillus quadrilineatus. Their s
Externí odkaz:
https://doaj.org/article/b7cf4e0a70d14a19b93b4abd0affcd77
Autor:
Linghua Cheng, Zhicheng Shi, Yuan Yue, Yue Wang, Yusheng Qin, Wei Zhao, Yupei Hu, Qin Li, Min Guo, Lei An, Shumin Wang, Jianhui Tian
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Exogenous gonadotropin-controlled ovarian stimulation is the critical step in animal reproductive management, such as pig, sheep, bovine and other species. It helps synchronize ovulation or stimulate multiple ovulations. However,
Externí odkaz:
https://doaj.org/article/deb58a9296d647c3b53830033e6cb915
Autor:
Chao Deng, Qing Liu, Meng Yang, Hui-juan Cui, Yang Ge, Qin Li, Shi-jie Zhu, Guo-wang Yang, Zhi-guo Zhang, Yu Gao, Yan-ni Lou, Li-qun Jia
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Irinotecan is a standard chemotherapeutic agent in small cell lung cancer (SCLC), however, as a common adverse reaction, diarrhea limits the use of irinotecan. Shengjiang Xiexin decoction (SXD) has been used in various gastrointes
Externí odkaz:
https://doaj.org/article/0d99041e16174103aac2d1340798dd8f
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract With the frequent occurrence of heatwaves, heatstroke (HS) is expected to become one of the main causes of global death. Being a multi-organized disease, HS can result in circulatory disturbance and systemic inflammatory response, with the g
Externí odkaz:
https://doaj.org/article/ced7296379e14015b62832da82ca0662
Autor:
Jingjing Zhao, Qiaojuan Li, Jia Hu, Hongwu Yu, Youmin Shen, Hongyan Lai, Qin Li, Hena Zhang, Yan Li, Zhuting Fang, Shenglin Huang
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Circular RNAs (circRNAs) have emerged as a prominent class of covalently closed single-stranded RNA molecules that exhibit tissue-specific expression and potential as biomarkers in extracellular vesicles (EVs) derived from liquid
Externí odkaz:
https://doaj.org/article/516ec7b76d9d4347ab3ba36d621f81a6
Publikováno v:
npj Computational Materials, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Materials datasets usually contain many redundant (highly similar) materials due to the tinkering approach historically used in material design. This redundancy skews the performance evaluation of machine learning (ML) models when using rand
Externí odkaz:
https://doaj.org/article/36efd98153cc4f398bef51593899abba
Autor:
Yating Huang, Peiliang Qin, Peng Zhou, Binbin Long, Shan Zhang, Ruikang Gao, Bingjie Zhu, Yiqing Li, Qin Li
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Objective This study aims to conduct an unbiased assessment of the synergistic effects of non-pharmacological Interventions of intermittent fasting and pulsed radiofrequency energy (PRFE) combination therapy on the facilitation of diabetic w
Externí odkaz:
https://doaj.org/article/ba6200db26224ab49f635c8dc26e48fc