Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Qin Kuang"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-27 (2024)
Abstract Background The failure of proper recognition of the intricate nature of pathophysiology in colorectal cancer (CRC) has a substantial effect on the progress of developing novel medications and targeted therapy approaches. Imbalances in the pr
Externí odkaz:
https://doaj.org/article/71b0e2c261b445a7b85726589cfffb37
Autor:
Bobo Li, Xiaokang Guo, Jiaqi Yu, Hongfu Sun, Xiaoming Zhao, Yan Sun, Xianling Dai, Qin Kuang, Jimao Ling, Jie Liu
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106400- (2024)
Obesity stress and its associated metabolic disruption increase the likelihood and advancement of several forms of malignancies, such as postmenopausal lung cancer in humans. Also, the mechanism of lung cancer stress-related cognitive impairment and
Externí odkaz:
https://doaj.org/article/29ac1fb25e944d6bbfdfe5083e87c20a
Autor:
Yameng Xie, Fuli Sun, Kuan Chang, Guang Li, Zhijia Song, Jiayu Huang, Xiqing Cheng, Guilin Zhuang, Qin Kuang
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Metal–organic frameworks (MOF) derived nitrogen‐doped carbon‐supported monodisperse Fe (Fe–N–C) catalysts are intensively studied, but great challenges remain in understanding the relationship between the coordination structure and
Externí odkaz:
https://doaj.org/article/579dcd9550184f54b65b8a18ffddec30
Autor:
Minxuan Xu, Jun Tan, Xin Liu, Li Han, Chenxu Ge, Yujie Zhang, Fufang Luo, Zhongqin Wang, Xiaoqin Xue, Liangyin Xiong, Xin Wang, Qinqin Zhang, Xiaoxin Wang, Qin Tian, Shuguang Zhang, Qingkun Meng, Xianling Dai, Qin Kuang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Chunxiao Chang, Bochu Wang, Jie Chai, Shengbin Shi, Lianyi Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Currently potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) and NASH-related pathopoiesis have failed to achieve expected therapeutic efficacy due to the complexity of the pathogenic mechanisms. Here we sho
Externí odkaz:
https://doaj.org/article/943a31ce33744632ade862d192f16e2d
Autor:
Chenxu Ge, Jun Tan, Deshuai Lou, Liancai Zhu, Zixuan Zhong, Xianling Dai, Yan Sun, Qin Kuang, Junjie Zhao, Longyan Wang, Jin Liu, Bochu Wang, Minxuan Xu
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102953- (2023)
Externí odkaz:
https://doaj.org/article/8b382a1242d7440c9005fa827257fd13
Autor:
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Yi Zhang, Fufeng Gao, Xianling Dai, Qin Kuang, Jie Chai, Benkui Zou, Bochu Wang
Publikováno v:
Advanced Science, Vol 10, Iss 36, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/b2b03cd6c69e4d4b872a65033fbc624e
Autor:
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Wei Dong, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Jing Feng, Bochu Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1071-1092 (2023)
Nowadays potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) have failed to achieve expected therapeutic efficacy because the pathogenic mechanisms are underestimated. Inactive rhomboid protein 2 (IRHOM2), a promising
Externí odkaz:
https://doaj.org/article/2496923f2e6942078d6f996b083ac336
Autor:
Chenxu Ge, Jun Tan, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Yan Sun, Jing Luo, Chufeng Zhang, Liancai Zhu, Bochu Wang, Minxuan Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Mechanisms underlying the pathogenesis of nonalcoholic steatohepatitis are unclear. Here, the authors show that ROS-mediated DUSP22 degradation participates in the progression of fatty liver, contributing to the development of NASH and associated HCC
Externí odkaz:
https://doaj.org/article/5ea402ac4e5241809e0364f9ae48f4ff
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Prostate cancer is currently the most common malignancy among men. Given the limitations of current conventional anticancer therapies, new high-risk treatments are urgently needed. Previous studies have shown that embryonic stem cells (ESCs) can reve
Externí odkaz:
https://doaj.org/article/2bf03bb90ec342809f9a2584308c87f0
Autor:
Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng, Liancai Zhu, Chenxu Ge, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Tingting Tang, Junjie Zhao, Longyan Wang, Jin Liu, Hao Wei, Yan Sun, Qiufeng Yang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Mingxin Xiong, Jing Feng, Chufeng Zhang, Bochu Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Nonalcoholic steatohepatitis (NASH) is a chronic liver disease with complex disease mechanisms. Here the authors report that the E3 ubiquitin-protein ligase Trim31 mitigates development of NASH via inhibition of rhomboid 5 homolog 2 (Rhbdf2) in mice.
Externí odkaz:
https://doaj.org/article/21bc4d0042064139960459afd8cbe022