Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Qilan Ning"'
Autor:
Jing Xu, Congshan Jiang, Yongsong Cai, Yuanxu Guo, Xipeng Wang, Jiaxiang Zhang, Jiawen Xu, Ke Xu, Wenhua Zhu, Si Wang, Fujun Zhang, Manman Geng, Yan Han, Qilan Ning, Peng Xu, Liesu Meng, Shemin Lu
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Objective The disruption of metabolic events and changes to nutrient and oxygen availability due to sustained inflammation in RA increases the demand of bioenergetic and biosynthetic processes within the damaged tissue. The current study aim
Externí odkaz:
https://doaj.org/article/32a38bbf4ff042e5a0096b449f13f9f3
Autor:
Xi Lan, Nan Wu, Litao Wu, Kai Qu, Ezra Kombo Osoro, Dongxian Guan, Xiaojuan Du, Bo Wang, Sifan Chen, Ji Miao, Juan Ren, Li Liu, Haiyun Li, Qilan Ning, Dongmin Li, Shemin Lu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 468-479 (2020)
Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer and the leading cause of cancer mortality. Several lines of evidence have demonstrated the aberrant expression of long noncoding RNAs (lncRNAs) in carcinogenesis and their universal
Externí odkaz:
https://doaj.org/article/da9b1332c6094dfda32e8afc505f995a
Autor:
Xi Lan, Litao Wu, Nan Wu, Qian Chen, Yue Li, Xiaojuan Du, Chenxi Wei, Lina Feng, Yazhao Li, Ezra Kombo Osoro, Mengyao Sun, Qilan Ning, Xiaofei Yan, Xudong Yang, Dongmin Li, Shemin Lu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 954-965 (2019)
Nonalcoholic fatty liver disease (NAFLD) is due to the excessive lipid accumulation within hepatocytes. Metabolic nuclear receptors (MNRs) play great roles in lipid homeostasis. We have identified a novel long noncoding RNA (lncRNA), lnc-HC, which re
Externí odkaz:
https://doaj.org/article/7bc770f9cd4e4d4491e89c41eb40816e
Autor:
Jian Sun, Ph. D., Quancheng Wang, Ying Yuan, Safdar Hussain, Ph. D., Yitong Zhao, Yuanxu Guo, Ph. D., Mengyao Sun, Ph. D., Huang Huang, Xinyu Huo, Fujun Zhang, Qilan Ning, Yan Han, Peng Xu, M.D., Ph. D., Shemin Lu, M.D., Ph. D.
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 2, Pp 100161- (2021)
Objective: Through experiments to testify a candidate novel miRNA previously discovered by us is a real miRNA and involved in cartilage development. Design: The miR-novel and the newly hairpin miRNA transcribed sequence (pre-miR-novel) was verified a
Externí odkaz:
https://doaj.org/article/4ae0c585c2fa485194b5f6945a1a9365
Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes
Autor:
Congshan Jiang, Jing Xu, Wenhua Zhu, Yongsong Cai, Si Wang, Yuanxu Guo, Ke Xu, Manman Geng, Nazim Hussain, Yan Han, Fujun Zhang, Qilan Ning, Liesu Meng, Shemin Lu
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Dysregulation of multiple microRNAs widely takes place during rheumatoid arthritis (RA) and experimental arthritides. This study is performed to explore the possible mechanism underlying DICER1 deficiency-mediated inflammation in human synoviocytes S
Externí odkaz:
https://doaj.org/article/2418e010b18b4f309afecee4207b1199
Autor:
Xiaoying Jiang, Qilan Ning
Publikováno v:
Biochemistry and Molecular Biology Education. 50:494-501
The COVID-19 pandemic has greatly impacted the education of international students. The authors taught a molecular biology course using the DingTalk platform for international medical students (IMS) in the autumn semester of 2020. We assessed the eff
Autor:
Fujun Zhang, Si Wang, Ke Xu, Yuanxu Guo, Jiaxiang Zhang, Qilan Ning, Wenhua Zhu, Congshan Jiang, Jing Xu, Yan Han, Manman Geng, Jiawen Xu, Shemin Lu, Xipeng Wang, Liesu Meng, Yongsong Cai, Peng Xu
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-13 (2020)
Arthritis Research & Therapy
Arthritis Research & Therapy
Objective The disruption of metabolic events and changes to nutrient and oxygen availability due to sustained inflammation in RA increases the demand of bioenergetic and biosynthetic processes within the damaged tissue. The current study aimed to und
Autor:
Wenhua Zhu, Congshan Jiang, Liesu Meng, Si Wang, Fujun Zhang, Shemin Lu, Xipeng Wang, Yizhao Peng, Pei Tao, Xiaowei Li, Yan Han, Manman Geng, Jing Xu, Qilan Ning, Yuanxu Guo
Publikováno v:
The Journal of Immunology. 205:181-192
Recent studies indicate that glucose metabolism is altered in rheumatoid arthritis. We hypothesize that Pkm2, as a key regulatory enzyme of glycolysis pathway, triggers the activation of macrophages (Mφ), which results in proinflammatory cytokine pr
Autor:
Ezra Kombo Osoro, Dongxian Guan, Kai Qu, Xiaojuan Du, Sifan Chen, Haiyun Li, Shemin Lu, Qilan Ning, Nan Wu, Bo Wang, Dongmin Li, Ji Miao, Juan Ren, Xi Lan, Li Liu, Litao Wu
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 20, Iss, Pp 468-479 (2020)
Molecular Therapy: Nucleic Acids, Vol 20, Iss, Pp 468-479 (2020)
Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer and the leading cause of cancer mortality. Several lines of evidence have demonstrated the aberrant expression of long noncoding RNAs (lncRNAs) in carcinogenesis and their universal
Autor:
Yitong Zhao, Yuanxu Guo, Mengyao Sun, Safdar Hussion, Ying Zheng, Huang Huang, Xinyu Huo, Yutong Zhao, Fujun Zhang, Yan Han, Qilan Ning, Peng Xu, Jian Sun, Shemin Lu
Publikováno v:
Journal of bone and mineral metabolism. 40(6)
Selenium (Se) as well as selenoproteins are vital for osteochondral system development. Se deficiency (SeD) has a definite impact on the expression and activity of histone deacetylases (HDACs). Abnormal expression of some HDACs affects cartilage deve