Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Qijin Zhao"'
Autor:
Qian Jiang, Qijin Zhao, Yibing Chen, Chunxiao Ma, Xiaohong Peng, Xi Wu, Xingfeng Liu, Ruoran Wang, Shaocong Hou, Lijuan Kong, Yanjun Wan, Shusen Wang, Zhuo-Xian Meng, Bing Cui, Liangyi Chen, Pingping Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract In diabetes, macrophages and inflammation are increased in the islets, along with β-cell dysfunction. Here, we demonstrate that galectin-3 (Gal3), mainly produced and secreted by macrophages, is elevated in islets from both high-fat diet (H
Externí odkaz:
https://doaj.org/article/28370ccde98e41a8a0ad740a4d1c16e9
Autor:
Lijuan Kong, Qijin Zhao, Xiaojing Jiang, Jinping Hu, Qian Jiang, Li Sheng, Xiaohong Peng, Shusen Wang, Yibing Chen, Yanjun Wan, Shaocong Hou, Xingfeng Liu, Chunxiao Ma, Yan Li, Li Quan, Liangyi Chen, Bing Cui, Pingping Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract β-Cell dysfunction and β-cell loss are hallmarks of type 2 diabetes (T2D). Here, we found that trimethylamine N-oxide (TMAO) at a similar concentration to that found in diabetes could directly decrease glucose-stimulated insulin secretion
Externí odkaz:
https://doaj.org/article/e17213df7202427e96bb62e7c672007e
Autor:
Lei Ying, Luyao Wang, Kaiwen Guo, Yushu Hou, Na Li, Shuyi Wang, Xingfeng Liu, Qijin Zhao, Jie Zhou, Longwei Zhao, Jianlou Niu, Chuchu Chen, Lintao Song, Shaocong Hou, Lijuan Kong, Xiaokun Li, Jun Ren, Pingping Li, Moosa Mohammadi, Zhifeng Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Fibroblast growth factors are involved in systemic glucose homeostasis and of interest for developing therapies for type 2 diabetes and associated metabolic diseases. Here the authors identify paracrine FGF4 as an anti-hyperglycemic FGF, which target
Externí odkaz:
https://doaj.org/article/a9437ca24736421b818a2033c329bf9d
Autor:
Qijin Zhao, Baoquan Mao, Junyan Zhao, Huaying Li, Shuguang Wei, Xianghua Bai, Xinxi Zhang, Yunyin Zhang
Publikováno v:
Case Studies in Thermal Engineering, Vol 40, Iss , Pp 102495- (2022)
The heat transfer of fluids in pipelines under conditions with variable thermophysical parameters is ubiquitous in engineering applications, but effective methods to predict the heat transfer parameters are scarce. To address this issue, an experimen
Externí odkaz:
https://doaj.org/article/bbccc7ee8b9040eb9a337c759b1879e1
Publikováno v:
Case Studies in Thermal Engineering, Vol 36, Iss , Pp 102218- (2022)
Conventional electric heating methods applied when evaluating the natural convection heat transfer parameters at the outer walls of cylinders produce uneven heat flows and large measurement errors. The present work addresses these issues by developin
Externí odkaz:
https://doaj.org/article/2b2be0de8583453caffb254a1df5a57a
Publikováno v:
Laparoscopic, Endoscopic and Robotic Surgery, Vol 3, Iss 4, Pp 116-119 (2020)
Objective: Rising cesarean section rates have led to an increase in cesarean scar defects. However, there is no consensus regarding the gold standard for treating cesarean scar defects. This study aims to compare the efficacy of laparoscopy combined
Externí odkaz:
https://doaj.org/article/46bbc14a090148f9b140595ff4dd5548
Publikováno v:
Advances in Mechanical Engineering, Vol 13 (2021)
Mn-Cu high damping alloy is a twin-type damping alloy. Owing to its martensite twin structure at room temperature, it can convert vibration energy into heat energy, thereby reducing vibration. Although essentially a nonlinear elastic material, Mn-Cu
Externí odkaz:
https://doaj.org/article/68531adb0ea14dd2b9c0790da57271cd
Publikováno v:
Materials, Vol 13, Iss 9, p 2020 (2020)
To better describe its constitutive relation, we need a new constitutive equation for an important nonlinear elastic material, Mn-Cu damping alloy. In this work, we studied the nonlinear and hysteretic characteristics of the stress-strain curve of th
Externí odkaz:
https://doaj.org/article/a05ab4bf7cff4bb98bf1a2ceaf12a8d0
Autor:
Weibin Zha, Guangji Wang, Weiren Xu, Xuyuan Liu, Yun Wang, Beth S Zha, Jian Shi, Qijin Zhao, Phillip M Gerk, Elaine Studer, Phillip B Hylemon, William M Pandak, Huiping Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54349 (2013)
BackgroundHIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases. We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammato
Externí odkaz:
https://doaj.org/article/48ba76f137a34e8ab09360090c8231ae
Autor:
Xingfeng Liu, Kai Wang, Shaocong Hou, Qian Jiang, Chunxiao Ma, Qijin Zhao, Lijuan Kong, Jingwen Chen, Zhenhe Wang, Huabing Zhang, Tao Yuan, Yuxiu Li, Yi Huan, Zhufang Shen, Zhuowei Hu, Zhifeng Huang, Bing Cui, Pingping Li
Publikováno v:
Nature Metabolism. 4:1202-1213
Insulin signaling is essential for glucose metabolism, and insulin decreases insulin receptor (InsR) levels in a dose-dependent and time-dependent manner. However, the regulatory mechanisms of InsR reduction upon insulin stimulation remain poorly und