Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Qifang Xu"'
Autor:
Jason S. Wasserman, Bulat Faezov, Kishan R. Patel, Alison M. Kurimchak, Seren M. Palacio, David J. Glass, Holly Fowle, Brennan C. McEwan, Qifang Xu, Ziran Zhao, Lauren Cressey, Neil Johnson, James S. Duncan, Arminja N. Kettenbach, Roland L. Dunbrack, Xavier Graña
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B regulatory subunits. Here, we report the identification of a substrate conserved motif [RK]-V-x-x-[VI
Externí odkaz:
https://doaj.org/article/6e9017a5c5d34b82817862a82164f6a6
Autor:
Qifang Xu, Roland L. Dunbrack
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The authors previously developed the Protein Common Interface Database (ProtCID), which compares and clusters the interfaces of pairs of full-length protein chains with defined Pfam domain architectures in different PDB entries to identify biological
Externí odkaz:
https://doaj.org/article/8d7404b0d08849d28b4e85321f97f6ba
Autor:
Holly Fowle, Ziran Zhao, Qifang Xu, Jason S Wasserman, Xinru Wang, Mary Adeyemi, Felicity Feiser, Alison N Kurimchak, Diba Atar, Brennan C McEwan, Arminja N Kettenbach, Rebecca Page, Wolfgang Peti, Roland L Dunbrack, Xavier Graña
Publikováno v:
eLife, Vol 10 (2021)
Protein phosphorylation is a reversible post-translation modification essential in cell signaling. This study addresses a long-standing question as to how the most abundant serine/threonine protein phosphatase 2 (PP2A) holoenzyme, PP2A/B55α, specifi
Externí odkaz:
https://doaj.org/article/6761c6a9c42749159283c5b22082407f
Autor:
Friedrich Kueppers, Mark D. Andrake, Qifang Xu, Roland L. Dunbrack, Joannah Kim, Christopher L. Sanders
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Alpha 1 Antitrypsin (AAT) is a key serum proteinase inhibitor encoded by SERPINA1. Sequence variants of the gene can cause Alpha 1 Antitrypsin Deficiency (AATD), a condition associated with lung and liver disease. The majority of
Externí odkaz:
https://doaj.org/article/d32b605cb01a47899ade581892491c43
Autor:
Qifang Xu, Roland Dunbrack
Publikováno v:
Nucleic Acids Research. 51:D466-D478
Proteins often act through oligomeric interactions with other proteins. X-ray crystallography and cryo-electron microscopy provide detailed information on the structures of biological assemblies, defined as the most likely biologically relevant struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cc769d00d423b98c5aabbebba78e0f
https://doi.org/10.1093/nar/gkac937
https://doi.org/10.1093/nar/gkac937
Autor:
Hugo Schweke, Qifang Xu, Gerardo Tauriello, Lorenzo Pantolini, Torsten Schwede, Frédéric Cazals, Alix Lhéritier, Juan Fernandez-Recio, Luis Ángel Rodríguez-Lumbreras, Ora Schueler-Furman, Julia K. Varga, Brian Jiménez-García, Manon F. Réau, Alexandre Bonvin, Castrense Savojardo, Pier-Luigi Martelli, Rita Casadio, Jérôme Tubiana, Haim Wolfson, Romina Oliva, Didier Barradas-Bautista, Tiziana Ricciardelli, Luigi Cavallo, Česlovas Venclovas, Kliment Olechnovič, Raphael Guerois, Jessica Andreani, Juliette Martin, Xiao Wang, Daisuke Kihara, Anthony Marchand, Bruno Correia, Xiaoqin Zou, Sucharita Dey, Roland Dunbrack, Emmanuel Levy, Shoshana Wodak
Reliably scoring and ranking candidate models of protein complexes and assigning their oligomeric state from the structure of the crystal lattice represent outstanding challenges. A community-wide effort was launched to tackle these challenges. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adaf2d977a6fae24f92d44626aa47f9a
https://doi.org/10.22541/au.167569565.51141128/v1
https://doi.org/10.22541/au.167569565.51141128/v1
Autor:
Simon Kelow, Bulat Faezov, Qifang Xu, Mitchell Parker, Jared Adolf-Bryfogle, Roland L. Dunbrack
Antibody complementarity determining regions (CDRs) are loops within antibodies responsible for engaging antigens during the immune response and in antibody therapeutics and laboratory reagents. Since the 1980s, the conformations of the hypervariable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e24965aa3f96efe26f02adbfec0afc5
https://doi.org/10.1101/2022.10.12.511988
https://doi.org/10.1101/2022.10.12.511988
Autor:
Alison N Kurimchak, Rebecca Page, Brennan C McEwan, Arminja N. Kettenbach, Wolfgang Peti, Holly Fowle, Xavier Graña, Qifang Xu, Jason S. Wasserman, Xinru Wang, Ziran Zhao, Roland L. Dunbrack, Diba Atar, Mary Adeyemi, Felicity Feiser
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Protein phosphorylation is a reversible post-translation modification essential in cell signaling. This study addresses a long-standing question as to how the most abundant serine/threonine protein phosphatase 2 (PP2A) holoenzyme, PP2A/B55α, specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3ec302472311e87c32e0b164ec9980
https://doi.org/10.7554/elife.63181
https://doi.org/10.7554/elife.63181
Autor:
Alison N Kurimchak, Rebecca Page, Jason S. Wasserman, Holly Fowle, Arminja N. Kettenbach, Felicity Feiser, Xavier Graña, Wolfgang Peti, Xinru Wang, Diba Atar, Qifang Xu, Roland L. Dunbrack, Brennan C McEwan, Mary Adeyemi, Ziran Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6e0cc5ebe4ae4229a838aedcf3ca4e0
https://doi.org/10.7554/elife.63181.sa2
https://doi.org/10.7554/elife.63181.sa2
Publikováno v:
Optics Communications. 449:19-23
By controlling the on–off state of light emitting diode (LED), data can be modulated onto the visible light. By exploiting the rolling shutter effect (RSE) of camera image sensor, the data can be demodulated from the light correspondingly. Based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83c58d9d8563113f7aca59872c728ef
https://doi.org/10.1016/j.optcom.2019.05.028
https://doi.org/10.1016/j.optcom.2019.05.028