Výsledky vyhledávání

A novel and cost-efficient allele-specific PCR method for multiple SNP genotyping in a single run

Autor: Qidi He, Ou Hu, Meng Chen, Zhixian Liang, Lushan Liang, Zuanguang Chen

Publikováno v: Analytica chimica acta. 1229

Cost-effective methods for DNA genotyping were needed because single nucleotide polymorphisms (SNPs) were essential biomarkers associated with many diseases. Allele-specific PCR (AS-PCR) has the advantages of mature instruments and high sensitivity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f67f05358e3eefd74d9756dcfdf781
https://pubmed.ncbi.nlm.nih.gov/36156224

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Determination of tuberculosis-related volatile organic biomarker methyl nicotinate in vapor using fluorescent assay based on quantum dots and cobalt-containing porphyrin nanosheets

Autor: Qidi He, Shuangshuang Cai, Jinghao Wu, Ou Hu, Lushan Liang, Zuanguang Chen

Publikováno v: Microchimica Acta. 189

Methyl nicotinate (MN) is a representative and typical volatile organic marker of Mycobacterium tuberculosis, and the specific detection of MN in human breath facilitates non-invasive, rapid, and accurate epidemic screening of tuberculosis infection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a5276841ad625d623b35ead7c89f1f
https://doi.org/10.1007/s00604-022-05212-w

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A novel fluorescence method based on loop-mediated isothermal amplification and universal molecular beacon in Mycobacterium tuberculosis detection

Autor: Lushan Liang, Meng Chen, Ou Hu, Qidi He, Zuanguang Chen

Publikováno v: Talanta. 253:123996

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71bad5d6b7c9aeaad4ae15348817381f
https://doi.org/10.1016/j.talanta.2022.123996

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Remaining Allele-Specific Pcr Primer-Triggered Rolling Circle Amplification for Dual Snp Genotyping Of Adh1b And Aldh2 Genes

Autor: Qidi He, Ou Hu, Meng Chen, Zhixian Liang, Lushan Liang, Zuanguang Chen

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6edf11709fcb6712f6fb81ee360c15db
https://doi.org/10.2139/ssrn.4111262

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An electrochemical dual-aptamer biosensor based on metal-organic frameworks MIL-53 decorated with Au@Pt nanoparticles and enzymes for detection of COVID-19 nucleocapsid protein

Autor: Zuanguang Chen, Ou Hu, Duanping Sun, Zhixian Liang, Jinju Tian, Qidi He

Publikováno v: Electrochimica Acta. 387:138553

The development of COVID-19 detection strategies with high sensitivity and selectivity are urgent for early diagnosis. Herein, we constructed an electrochemical dual-aptamer biosensor based on the metal-organic frameworks MIL-53(Al) decorated with Au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed99663b2807668722c6b3321dbe915c
https://doi.org/10.1016/j.electacta.2021.138553

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A universal fluorescent sensing system for pathogen determination based on loop-mediated isothermal amplification triggering dual-primer rolling circle extension

Autor: Zuanguang Chen, Meng Chen, Yanli Tong, Qidi He

Publikováno v: Sensors and Actuators B: Chemical. 331:129436

The great challenge for loop-mediated isothermal amplification (LAMP) is target-specific detection. However, the most popular fluorogenic probe method needs complicated sequence design and large reagent consumption. Rolling circle amplification (RCA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d566cdeb596cedf64dd2c5dfabfefaaf
https://doi.org/10.1016/j.snb.2021.129436

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Developmental Toxicity and Potential Teratogenicity of Compound Danshen Tablet, Angong Niuhuang Pill, and Lidan Paishi Tablet in Zebrafish Embryos

Autor: Zuanguang Chen, Jiefeng Chen, Qidi He, Danping Huang, Meicun Yao, Liu Tong

Publikováno v: Chinese Herbal Medicines. 9:74-79

Objective Herbal medicines containing toxic herbs or minerals such as Compound Danshen Tablet (CDT), Angong Niuhuang Pill (ANP), and Lidan Paishi Tablet (LPT) are avoided or used with caution for pregnant women because of potential teratogenicity. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3b36d1e8692302e752e29867676c9ce
https://doi.org/10.1016/s1674-6384(17)60079-0

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Allele-specific PCR with a novel data processing method based on difference value for single nucleotide polymorphism genotyping of ALDH2 gene

Autor: Meng Chen, Qidi He, Zuanguang Chen, Xiangan Lin

Publikováno v: Talanta. 220:121432

Single nucleotide polymorphism (SNP) analysis based on allele-specific polymerase chain reaction (AS-PCR) is a relatively effective and economical method compared with other genotyping technologies such as DNA sequencing, DNA hybridization and isothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4993d119da02ea797089f1a90af81c0
https://doi.org/10.1016/j.talanta.2020.121432

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Developmental Toxicity of Diethylnitrosamine in Zebrafish Embryos/Juveniles Related to Excessive Oxidative Stress

Autor: Zuanguang Chen, Hongzhi Yang, Danping Huang, Weiqu Yuan, Hanmin Li, Qidi He

Publikováno v: Water, Air, and Soil Pollution

Diethylnitrosamine (DEN) is present in food, water, and daily supplies and is regarded as a toxicant of carcinogenicity. The developmental toxicity of DEN has been rarely reported as yet. In this study, zebrafish were exposed to different concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cfec6fa3fcd1ac949210b8c8d619cd
http://europepmc.org/articles/PMC5823957

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