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Development and validation of an UPLC-MS/MS method for determination of jujuboside B in rat plasma and its application in pharmacokinetic and bioavailability studies

Autor: Ruijie Chen, Zheng Xiang, Xiaoyong Zheng, Xiangxiang Yang, Qiaoyan Le, Shuangshuang Zhang

Publikováno v: Analytical Methods. 7:4049-4054

Jujuboside B (JuB) is a main bioactive saponin constituent of Ziziphi Spinosae Semen. The compound is used clinically as an anti-insomnia and anti-anxiety medicine. In this study, a sensitive, simple, and rapid ultra performance liquid chromatography

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b542b26ced6bc695e56a1ceb0765afc
https://doi.org/10.1039/c5ay00413f

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Publikováno v: Analytical Methods; 5/21/2015, Vol. 7 Issue 10, p4017-4029, 13p

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Akademický článek

Development and validation of an UPLC-MS/MS method for determination of jujuboside B in rat plasma and its application in pharmacokinetic and bioavailability studies.

Autor: Zheng, Xiaoyong, Yang, Xiangxiang, Le, Qiaoyan, Zhang, Shuangshuang, Chen, Ruijie, Xiang, Zheng

Publikováno v: Analytical Methods; 5/21/2015, Vol. 7 Issue 10, p4049-4054, 6p

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