Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Qiaojie Xiong"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The auditory striatum, a sensory portion of the dorsal striatum, plays an essential role in learning and memory. In contrast to its roles and underlying mechanisms in operant conditioning, however, little is known about its contribution to c
Externí odkaz:
https://doaj.org/article/b794528a023842698c38f27e78af01e3
Autor:
Allen P. F. Chen, Jeffrey M. Malgady, Lu Chen, Kaiyo W. Shi, Eileen Cheng, Joshua L. Plotkin, Shaoyu Ge, Qiaojie Xiong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The auditory striatum, the tail portion of dorsal striatum, is implicated in decision-making. This study uncovers a phasic mechanism within the nigrostriatal system that regulates auditory decisions by modulating ongoing auditory perception.
Externí odkaz:
https://doaj.org/article/4a06605773c347e08470742fd6f0dda1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Changes in wake/sleep architecture have been observed in both aged human and animal models, presumably due to various functional decay throughout the aging body particularly in the brain. Microglia have emerged as a modulator for wake/sleep architect
Externí odkaz:
https://doaj.org/article/21688a9aee4743118f177fe9ee295e57
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Here, the authors show that microglia depletion results in unstable wakefulness and altered levels of ceramide, influencing microglia in the mouse thalamic reticular nucleus (TRN). Stable wakefulness can be restored by activation of the TRN or inhibi
Externí odkaz:
https://doaj.org/article/85a4e328c23d4b989f9a8c639753deae
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Auditory-cued goal-oriented behaviors requires the participation of cortical and subcortical brain areas, but how neural circuits associate sensory-based decisions with goal locations through learning remains poorly understood. The hippocamp
Externí odkaz:
https://doaj.org/article/68eae5e86e724bfb8b6ce59f7e103502
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Selective attention modulates sensory cortical activity. It remains unclear how auditory cortical activity represents stimuli that differ behaviorally. We designed a cross-modality task in which mice made decisions to obtain rewards based on
Externí odkaz:
https://doaj.org/article/3a5fdf5d3a1241a7950eda034297f21b
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The precise role of auditory cortical and thalamic projections in the representation of sound in the auditory striatum is not known. Here, the authors show that silencing thalamic inputs lowers the gain of sound-evoked responses while cortical inputs
Externí odkaz:
https://doaj.org/article/88ccca7c4ae1464c8771b97fa69e4d15
Autor:
Gregory W. Kirschen, Rachel Kéry, Hanxiao Liu, Afrinash Ahamad, Liang Chen, Wendy Akmentin, Ramya Kumar, Joel Levine, Qiaojie Xiong, Shaoyu Ge
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract The adult brain actively controls its metabolic homeostasis via the circulatory system at the blood brain barrier interface. The mechanisms underlying the functional coupling from neuron to vessel remain poorly understood. Here, we establish
Externí odkaz:
https://doaj.org/article/0e8964114aca41bcb3f1a43c4fb128e3
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 647 (2021)
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS function. DA plays major roles in many behaviors including locomotion, learning, habit formation, perception, and memory processing. Reflecting this, DA dysregula
Externí odkaz:
https://doaj.org/article/7c25c139bee04681b6ca9d3dbb517057
Autor:
Gregory W Kirschen, Qiaojie Xiong
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 8, Pp 1225-1230 (2017)
The primary cilium, a hair-like sensory organelle found on most mammalian cells, has gained recent attention within the field of neuroscience. Although neural primary cilia have been known to play a role in embryonic central nervous system patterning
Externí odkaz:
https://doaj.org/article/a376cca2f0b34bcb8f26c15a8a32caf0