Výsledky vyhledávání - "Qiaodan Deng"

Akademický článek

SOSTDC1 Nuclear Translocation Facilitates BTIC Maintenance and CHD1‐Mediated HR Repair to Promote Tumor Progression and Olaparib Resistance in TNBC

Autor: Qiaodan Deng, Jiankun Qiang, Cuicui Liu, Jiajun Ding, Juchuanli Tu, Xueyan He, Jie Xia, Xilei Peng, Siqin Li, Xian Chen, Wei Ma, Lu Zhang, Yi‐Zhou Jiang, Zhi‐Ming Shao, Ceshi Chen, Suling Liu, Jiahui Xu, Lixing Zhang

Publikováno v: Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)

Abstract Breast tumor‐initiating cells (BTICs) of triple‐negative breast cancer (TNBC) tissues actively repair DNA and are resistant to treatments including chemotherapy, radiotherapy, and targeted therapy. Herein, it is found that a previously r

Externí odkaz: https://doaj.org/article/1e3b009041f14a21a1f006ddc2dac957

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Akademický článek

PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway

Autor: Rui Zhang, Mengxue Dong, Juchuanli Tu, Fengkai Li, Qiaodan Deng, Jiahui Xu, Xueyan He, Jiajun Ding, Jie Xia, Dandan Sheng, Zhaoxia Chang, Wei Ma, Haonan Dong, Yi Zhang, Lixing Zhang, Lu Zhang, Suling Liu

Publikováno v: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)

Abstract Our previous studies have showed that C-C motif chemokine ligand 20 (CCL20) advanced tumor progression and enhanced the chemoresistance of cancer cells by positively regulating breast cancer stem cell (BCSC) self-renewal. However, it is uncl

Externí odkaz: https://doaj.org/article/9223a8c700cb4717adae1b2da7a6fce0

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Akademický článek

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Autor: Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Vasculogenic mimicry (VM) contributes to the development of triple-negative breast cancer. In this study, the authors show that TEM8 is expressed in VM-forming breast cancer stem cells and it promotes stemness and VM differentiation capacity through

Externí odkaz: https://doaj.org/article/4d5dff66ab924a66a148c3c003c9bdec

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Akademický článek

Ccl3 enhances docetaxel chemosensitivity in breast cancer by triggering proinflammatory macrophage polarization

Autor: Tong Liu, Rui Zhang, Wei Ma, Dong Wang, Lei Zhou, Yin Liu, Dandan Sheng, Qiaodan Deng, Juchuanli Tu, Weilong Chen, Fuchuang Zhang, Nailong Gao, Mengxue Dong, Fengkai Li, Xueyan He, Shengzhong Duan, Lixing Zhang, Suling Liu

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)

Background Although the antitumor efficacy of docetaxel (DTX) has long been attributed to the antimitotic activities, its impact on the tumor microenvironment (TME) has recently gained more attention. Macrophages are a major component of the TME and

Externí odkaz: https://doaj.org/article/1b081b7b28a14d5d863ab610c0576c5f

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Akademický článek

Knockdown of Oligosaccharyltransferase Subunit Ribophorin 1 Induces Endoplasmic-Reticulum-Stress-Dependent Cell Apoptosis in Breast Cancer

Autor: Jiajun Ding, Jiahui Xu, Qiaodan Deng, Wei Ma, Rui Zhang, Xueyan He, Suling Liu, Lixing Zhang

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation. Though it has been verified that the abnormal glycosylation is closely related to the development of breast cancer, the det

Externí odkaz: https://doaj.org/article/6da03cac95164c21ab93aa445f99c353

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Data from ALDH1A1 Activity in Tumor-Initiating Cells Remodels Myeloid-Derived Suppressor Cells to Promote Breast Cancer Progression

Autor: Suling Liu, Lixing Zhang, Xiao-Yong Zhang, Zhi-Ming Shao, Qun-Ying Lei, Zuoren Yu, Jinhui Lv, Botao Zhao, Ying Liu, Xueyan He, Dong Wang, Lei Zhou, Lu Deng, Jie Xia, Qiaodan Deng, Jiankun Qiang, Cuicui Liu

Tumor-initiating cells (TIC) are associated with tumor initiation, growth, metastasis, and recurrence. Aldehyde dehydrogenase 1A1 (ALDH1A1) is a TIC marker in many cancers, including breast cancer. However, the molecular mechanisms underlying ALDH1A1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45341da67d9fe9588e603d447a3fac45
https://doi.org/10.1158/0008-5472.c.6513462.v1

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TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Autor: Xiaoli Yang, Suling Liu, Jiahui Xu, Xiaohong Yao, Xiu-Wu Bian, Qiaodan Deng, Jiankun Qiang, Xueyan He, Dong Wang, Lixing Zhang, Guojuan Jiang, Jiajun Ding, Cong Yang, Zhi-min Shao, Juchuanli Tu, Ronggui Hu, Qun-Ying Lei, Rui Zhang

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

Enhanced neovasculogenesis, especially vasculogenic mimicry (VM), contributes to the development of triple-negative breast cancer (TNBC). Breast tumor-initiating cells (BTICs) are involved in forming VM; however, the specific VM-forming BTIC populati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae363c4631253cfb04dce2b7e98dfad
https://doaj.org/article/4d5dff66ab924a66a148c3c003c9bdec

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