Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Qiao‑Juan Shi"'
Autor:
Bing Zhao, Meng Zhang, Xue Han, Xia-Yan Zhang, Qiong Xing, Xu Dong, Qiao-Juan Shi, Peng Huang, Yun-Bi Lu, Er-Qing Wei, Qiang Xia, Wei-Ping Zhang, Chun Tang
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85403 (2013)
Intracellular nicotinamide phosphoribosyltransferase (iNAMPT) in neuron has been known as a protective factor against cerebral ischemia through its enzymatic activity, but the role of central extracellular NAMPT (eNAMPT) is not clear. Here we show th
Externí odkaz:
https://doaj.org/article/23817fa8e7604625b2ffcfabfed82e4e
Publikováno v:
Toxicology and Applied Pharmacology. 470:116549
Publikováno v:
International Journal of Molecular Medicine
GPR17 is a G (i)-coupled dual receptor, linked to P2Y and CysLT receptors stimulated by uracil nucleotides and cysteinyl leukotrienes, respectively. Recent evidence has demonstrated that GPR17 inhibition ameliorates the progression of cerebral ischem
Autor:
Jing Huang, Qiao-Juan Shi, Ming Wu, Yun-Bi Lu, Ga-Qi Tu, San-Hua Fang, Bing Zhao, Jia-Tong Lu, Xian Xie, Wei-Ping Zhang, Chen-Xiang Chen, Er-Qing Wei
Publikováno v:
Neuroscience. 356:193-206
Nicotinamide phosphoribosyltransferase (NAMPT) is an important neuroprotective factor in cerebral ischemia, and it has been reported that NAMPT inhibitors can aggravate neuronal injury in the acute phase. However, because it is a cytokine, NAMPT part
Publikováno v:
Experimental and Therapeutic Medicine
Ampelopsin (AMP) is isolated from the Chinese medicinal herb Ampelopsis grossedentata (Hand-Mazz) and has been associated with numerous biological and pharmacological activities. However, it is not clear whether AMP has a direct protective effect on
Publikováno v:
Experimental and Therapeutic Medicine
Ischemic stroke is a highly complex pathological process that is divided into acute, subacute and chronic phases. Paeonol is a biologically active natural product with a variety of pharmacological effects, including those on neuronal activity. Howeve
Autor:
Wei-Ping Zhang, Yun Bi Lu, H.Z. Ying, Qiao-Juan Shi, Er-Qing Wei, Z.X. Liu, X.M. Song, San-Hua Fang, X.Y. Sa, Hui Wang
Publikováno v:
Neuroscience. 291:53-69
Cysteinyl leukotrienes (CysLTs) induce inflammatory responses by activating their receptors, CysLT1R and CysLT2R. We have reported that CysLT2R is involved in neuronal injury, astrocytosis, and microgliosis, and that intracerebroventricular (i.c.v.)
Autor:
Lu Chen, Qiao-Juan Shi, Shu-Ying Yu, Li-Hui Zhang, San-Hua Fang, Xia-Yan Zhang, Yun-Bi Lu, Wei-Ping Zhang, Dong-min Xu, Er-Qing Wei, Xiao-rong Wang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 346:328-341
The cysteinyl leukotrienes (CysLTs) are inflammatory mediators closely associated with neuronal injury after brain ischemia through the activation of their receptors, CysLT1R and CysLT2R. Here we investigated the involvement of both receptors in oxyg
Autor:
Bing Zhao, Wei-Ping Zhang, Qiao-Juan Shi, Dong-min Xu, Li Xiao, Er-Qing Wei, Yun-Bi Lu, Xiao-Ying Sa, Shu-Ying Yu, San-Hua Fang, Xia-Yan Zhang, Xiao-rong Wang
Publikováno v:
Brain Research. 1484:57-67
Cysteinyl leukotrienes (CysLTs) induce inflammatory responses by activating their receptors, CysLT 1 R and CysLT 2 R. We recently reported that CysLT 2 R is involved in neuronal injury, astrocytosis and microgliosis after focal cerebral ischemia in r
Publikováno v:
Die Pharmazie. 70(10)
APO866 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), and inhibits nicotinamide adenine dinucleotide (NAD) synthesis. Our previous study showed that APO866 inhibits the proliferation of C6 glioblastoma cells, but failed to i