Zobrazeno 1 - 10
of 503
pro vyhledávání: '"Qianjin, Lu"'
Autor:
Huiqi Yin, Liming Li, Xiwei Feng, Zijun Wang, Meiling Zheng, Junpeng Zhao, Xinyu Fan, Wei Wu, Lingyu Gao, Yijing Zhan, Ming Zhao, Qianjin Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Current therapies for systemic lupus erythematosus that target a particular factor or cell type exhibit limited effectiveness. To address this limitation, our focus was on CD132, a subunit common to six inflammatory factor receptors implicat
Externí odkaz:
https://doaj.org/article/74804ca15eb44cb9b4565b9d0d0b78da
Autor:
Lai Wang, Haoyuan Yin, Jiao Jiang, Qilin Li, Changxing Gao, Wenrui Li, Bo Zhang, Yue Xin, Hongyang Li, Ming Zhao, Qianjin Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4560-4576 (2024)
Tripterygium wilfordii Hook F (TWHF) is a traditional Chinese medicine widely used in the treatment of systemic lupus erythematosus (SLE), with triptolide (TP) as its main active ingredient. However, its side effects also induced by TP, especially he
Externí odkaz:
https://doaj.org/article/1de8887387b14b4e86e1b223f6513efb
Autor:
Feng Xiong, Kai Shen, Di Long, Suqing Zhou, Pinglang Ruan, Yue Xin, Yuezheng Xiao, Weijun Peng, Ming Yang, Haijing Wu, Qianjin Lu
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disorder that commonly affects the skin, kidneys, joints, and various other systemic tissues, with its development intricately linked to the process of immunosenescence. Quercetin (QC), a p
Externí odkaz:
https://doaj.org/article/aea139b397014f45a28f2a66cb4a2556
Autor:
Xiaomin Liu, Siyu Zhou, Mengjie Huang, Ming Zhao, Weiguang Zhang, Qun Liu, Kangkang Song, Xu Wang, Jiaona Liu, Qing OuYang, Zheyi Dong, Ming Yang, Zhenzhen Li, Li Lin, Yi Liu, Yang Yu, Simin Liao, Jian Zhu, Lin Liu, Wenge Li, Linpei Jia, Aihua Zhang, Chaomin Guo, LiuYang Yang, Qing gang Li, Xueyuan Bai, Ping Li, Guangyan Cai, Qianjin Lu, Xiangmei Chen
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus (SLE) patients and is associated with increased mortality. DNA methylation, one of the most important epigenetic modifications, has bee
Externí odkaz:
https://doaj.org/article/426356896e9e45d7bfca3833edd95a3a
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37432- (2024)
The regulation of immune functions and the maintenance of homeostasis in the internal environment are both integral to human gut microbiota (GM). If GM is disturbed, it can result in a range of autoimmune diseases, including chronic inflammatory skin
Externí odkaz:
https://doaj.org/article/1aba7c14cca74598902f3a35f411ce7e
Autor:
Yiran Chen, Xi Li, Ming Yang, Chen Jia, Zhenghao He, Suqing Zhou, Pinglang Ruan, Yikun Wang, Congli Tang, Wenjing Pan, Hai Long, Ming Zhao, Liwei Lu, Weijun Peng, Arne Akbar, Irene XY. Wu, Song Li, Haijing Wu, Qianjin Lu
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103422- (2024)
Time-restricted eating (TRE) has been shown to extent lifespans in drosophila and mouse models by affecting metabolic and anti-inflammatory activities. However, the effect of TRE on the human immune system, especially on immunosenescence, intestinal
Externí odkaz:
https://doaj.org/article/5b34704ffe524b89903fe434d3241eb1
Autor:
Changxing Gao, Mei Liu, Yue Xin, Yong Zeng, Hui Yang, Xinyu Fan, Cheng Zhao, Bo Zhang, Lingzhi Zhang, Jing J. Li, Ming Zhao, Zijun Wang, Qianjin Lu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Background The meticulous selection of appropriate vaccine adjuvants is crucial for optimizing immune responses. Traditionally, pemphigus vulgaris (PV), an autoimmune disorder, has been modelled using complete Freund's adjuvant (CFA). In thi
Externí odkaz:
https://doaj.org/article/606d8f8fe24f43149453c44ee5b9d6b9
Autor:
Pinglang Ruan, Ming Yang, Xinyi Lv, Kai Shen, Yiran Chen, Hongli Li, Di Zhao, Jianhua Huang, Yang Xiao, Weijun Peng, Haijing Wu, Qianjin Lu
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Coffee, a widely consumed beverage, has shown benefits for human health but lacks sufficient basic and clinical evidence to fully understand its impacts and mechanisms. Here, we conducted a cross‐sectional observational study of coffee con
Externí odkaz:
https://doaj.org/article/710193f7020845ad8ca3b727d4d2af24
Publikováno v:
Journal of Translational Autoimmunity, Vol 8, Iss , Pp 100232- (2024)
Externí odkaz:
https://doaj.org/article/2cf4676f57a244a684cca9fc7650df30
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Noncanonical pyroptosis is triggered by Caspase 4/5/11, which cleaves Gasdermin D (GSDMD), leading to cell lysis. While GSDMD has been studied previously in systemic lupus erythematosus (SLE), the role of pyroptosis in SLE pathogenesis remai
Externí odkaz:
https://doaj.org/article/7e47b3dc31904adba6e6b8619b2e8eee