Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Qiangrong Pan"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52706 (2013)
PURPOSE: Cancer drug resistance is a major obstacle for the success of chemotherapy. Since most clinical anticancer drugs could induce drug resistance, it is desired to develop candidate drugs that are highly efficacious but incompetent to induce dru
Externí odkaz:
https://doaj.org/article/acdb4f57dfb84d3d81c29b357f294ecc
Publikováno v:
PLoS ONE, Vol 7, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/f35a9404f03148a09b7f37758fc899b5
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28335 (2011)
To mitigate the cardiotoxicity of anthracycline antibiotics without compromising their anticancer activities is still an issue to be solved. We previously demonstrated that schisandrin B (Sch B) could protect against doxorubicin (Dox)-induced acute c
Externí odkaz:
https://doaj.org/article/db0bf56d39c948de8b18137e1c6fd26b
Defect in apoptotic signaling and up-regulation of drug transporters in cancer cells significantly limits the effectiveness of cancer chemotherapy. We propose that an agent inducing non-apoptotic cell death may overcome cancer drug resistance and sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9244690d46313a39b0de52ac5a13bb02
https://doi.org/10.1158/1535-7163.c.6531722.v1
https://doi.org/10.1158/1535-7163.c.6531722.v1
Supplementary Data from Shikonin circumvents cancer drug resistance by induction of a necroptotic death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2955e6610fcdea50c535986729398405
https://doi.org/10.1158/1535-7163.22485008
https://doi.org/10.1158/1535-7163.22485008
Publikováno v:
The Journal of Biological Chemistry
Previous studies have identified GAPDH as a promising target for treating cancer and modulating immunity because its inhibition reduces glycolysis in cells (cancer cells and immune cells) with the Warburg effect, a modified form of cellular metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d332adf7ec310c14c988541e3e3aa008
https://pubmed.ncbi.nlm.nih.gov/33545174
https://pubmed.ncbi.nlm.nih.gov/33545174
Publikováno v:
Life Sciences. 80:741-748
We recently reported that dibenzocyclooctadiene lignans were a novel class of P-glycoprotein (P-gp) inhibitors. In this study, we demonstrated that the lignans of this class were also effective inhibitors of multidrug resistance-associated protein 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96be80046b08a4375d337eac394499d3
https://doi.org/10.1016/j.lfs.2006.11.002
https://doi.org/10.1016/j.lfs.2006.11.002
Publikováno v:
Cancer Letters. 217:139-147
Human DNA polymerases kappa, eta, iota, and zeta are responsible for the translesion DNA synthesis. Numerous in vitro studies indicated that these enzymes may contribute to DNA lesion-triggered and spontaneous mutation. We measured the transcripts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6311dc5b2e8d68d6de8916ee54c0f941
https://doi.org/10.1016/j.canlet.2004.07.021
https://doi.org/10.1016/j.canlet.2004.07.021
Autor:
Jiansheng Xie, Chunyan Dai, Hao Wu, Xun Hu, Zonghui Ding, Bingyan Ji, Yan Luo, Danqing Hu, Qiangrong Pan
Publikováno v:
Scientific Reports
Warburg effect is a dominant phenotype of most cancer cells. Here we show that this phenotype depends on its environment. When cancer cells are under regular culture condition, they show Warburg effect; whereas under lactic acidosis, they show a nong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e311769601901dbaadc9f04f09341bc0
https://doi.org/10.1038/srep04927
https://doi.org/10.1038/srep04927
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52706 (2013)
PLoS ONE
PLoS ONE
Purpose Cancer drug resistance is a major obstacle for the success of chemotherapy. Since most clinical anticancer drugs could induce drug resistance, it is desired to develop candidate drugs that are highly efficacious but incompetent to induce drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf022a0f0692ee31eac9f517efaec8f
http://europepmc.org/articles/PMC3536779?pdf=render
http://europepmc.org/articles/PMC3536779?pdf=render