Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Qiangqiang Hou"'
Autor:
Xiaonan Pang, Siyu Fan, Yulin Zhang, Ting Zhang, Qiangqiang Hou, Yue Wu, Ye Zhang, Yanghua Tian, Kai Wang
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103640- (2024)
Background: Widespread functional alterations have been implicated in patients with generalized anxiety disorder (GAD). However, most studies have primarily focused on static brain network features in patients with GAD. The current research focused o
Externí odkaz:
https://doaj.org/article/2a580e8008b946cc86c7806dde027d86
Publikováno v:
Journal of Medicinal Chemistry. 66:4324-4341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40b235898479fae6c471c43cd220aae
https://doi.org/10.1021/acs.jmedchem.2c01729
https://doi.org/10.1021/acs.jmedchem.2c01729
Autor:
Ting Zhang, Xiaohui Xie, Qianqian Li, Lei Zhang, Yue Chen, Gong-Jun Ji, Qiangqiang Hou, Tianxia Li, Chunyan Zhu, Yanghua Tian, Kai Wang
Publikováno v:
Nature and Science of Sleep. 14:1009-1019
Ting Zhang,1â 3,* Xiaohui Xie,2â 4,* Qianqian Li,1â 3,* Lei Zhang,2,3,5,6 Yue Chen,2,4 Gong-Jun Ji,2,3,5 Qiangqiang Hou,2â 4 Tianxia Li,7 Chunyan Zhu,2,3,5,6 Yanghua Tian,4,8,9 Kai Wang2â 5,9 1Department of Psychi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7563e30ad95d93758dd344e90056cd2
https://doi.org/10.2147/nss.s358763
https://doi.org/10.2147/nss.s358763
Autor:
Jinying Yang, Kai Wang, Yanghua Tian, Ting Zhang, Wen Xie, Huaming Lv, Bensheng Qiu, Qiangqiang Hou, Shengchun Jin, Gong-Jun Ji, Tongjian Bai
Publikováno v:
Journal of Neuroscience Research. 100:477-489
Approximately two-thirds of major depressive disorder (MDD) patients have pain, which exacerbates the severity of depression. Electroconvulsive therapy (ECT) is an efficacious treatment that can alleviate depressive symptoms; however, treatment for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360aaad2f49e8c6080cc842a7eded4cc
https://doi.org/10.1002/jnr.24979
https://doi.org/10.1002/jnr.24979
Autor:
Xinyi Lv, Yanghua Tian, Kai Wang, Yue Wu, Qiang Wei, Yuanyuan Guo, Yang Ji, Nong Zhou, Yue Chen, Huaming Lv, Qiangqiang Hou
Publikováno v:
Brain Imaging and Behavior. 16:1065-1076
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a recently identified autoimmune disorder with heterogeneous neurological, psychiatric, and cognitive manifestations. The NMDAR is a key signaling node for neurovascular coupling, the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59c71a41997fee89e0fde1f51a02dbc
https://doi.org/10.1007/s11682-021-00588-4
https://doi.org/10.1007/s11682-021-00588-4
Publikováno v:
Neuroradiology. 64:493-502
This study aims to analyze the multimodal score of the regional pial collateral in predicting hemorrhagic transformation (HT) after mechanical thrombectomy in acute ischemic stroke (AIS). On the basis of different brain regions and multiphase compute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fe9252c082aa8a803d629b2d103416
https://doi.org/10.1007/s00234-021-02795-8
https://doi.org/10.1007/s00234-021-02795-8
Autor:
Xiaoyu Chen, Chengxia Shu, Wenqiang Li, Qiangqiang Hou, Guangmei Luo, Kexin Yang, Xiaoxing Wu
Publikováno v:
Journal of medicinal chemistry. 65(9)
The treatment of triple-negative breast cancer (TNBC) remains a huge clinical challenge and dual-targeted small-molecule drugs might provide new therapeutic options for this type of breast cancer. In this work, we discovered a series of SHP2 and CDK4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fe9d48b39e6bcee468c9883571280a
https://pubmed.ncbi.nlm.nih.gov/35447031
https://pubmed.ncbi.nlm.nih.gov/35447031
Publikováno v:
Bioorganic Chemistry. 119:105575
Since androgen receptor (AR) can bind to BRD4 protein and this binding can be blocked by BRD4 inhibitors, targeting BRD4 has emerged as a promising approach for the treatment of prostate cancer (PC). Herein, we designed and synthesized a series of 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95dfa87fb43c95fccea3861e3b9a7d0
https://doi.org/10.1016/j.bioorg.2021.105575
https://doi.org/10.1016/j.bioorg.2021.105575
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115763
A series of novel steroidal-chalcone derivates were designed and synthesized based on the molecular hybridization strategy and further evaluated for their growth inhibitory activity against three human cancer cell lines. The MTT results indicated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb5504d58d9f6609cc67e0af5d0bd7d
https://doi.org/10.1016/j.bmc.2020.115763
https://doi.org/10.1016/j.bmc.2020.115763
Publikováno v:
Steroids. 150
Both AR and CYP17 are important targets for blocking androgen signaling, and it has been accepted that multifunctional drugs have a low risk of drug resistance in the treatment of cancer. Thus, herein a series of steroidal imidazoles were designed, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b239a42f249ffc1a86b80b7b47c46d
https://pubmed.ncbi.nlm.nih.gov/30885648
https://pubmed.ncbi.nlm.nih.gov/30885648