Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Qiangbo Hou"'
Autor:
Jiali Yang, Jiafeng Zhu, Jiaojiao Sun, Yiyun Chen, Yaran Du, Yiling Tan, Linpeng Wu, Mengting Zhai, Lixiang Wei, Na Li, Ke Huang, Qiangbo Hou, Zhenbo Tong, Andreas Bechthold, Hao Tian, Zhenhua Sun, Chijian Zuo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 184-197 (2022)
The success of the two mRNA vaccines developed by Moderna and BioNTech during the COVID-19 pandemic increased research interest into the application of mRNA technologies. Compared with the canonical linear mRNA used in these vaccines, circular mRNA h
Externí odkaz:
https://doaj.org/article/8c8b3f2e71ad408e88adf7ed1fab8d11
Autor:
Zonghao Qiu, Qiangbo Hou, Yang Zhao, Jiafeng Zhu, Mengting Zhai, Daolei Li, Yi Li, Chunxi Liu, Na Li, Yifei Cao, Jiali Yang, Zhenhua Sun, Chijian Zuo
Translatable circular RNAs (circRNAs) are emerging as a crucial molecular format for transient protein expression, with high potential to be an alternative for linear mRNA to reshape the landscape of mRNA pharmaceutical industry. Canonical Anabaena p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb128390517f57258f2c5019356b2c1e
https://doi.org/10.1101/2022.06.20.496777
https://doi.org/10.1101/2022.06.20.496777
Autor:
Ke Huang, Na Li, Yingwen Li, Jiafeng Zhu, Qianyi Fan, Jiali Yang, Yinjia Gao, Yupin Liu, Qiangbo Hou, Shufeng Gao, Ke Wei, Chao Deng, Chijian Zuo, Zhenhua Sun
mRNA vaccines have emerged as a most promising and potent platform in the fight against various diseases including the COVID-19 pandemic. However, the intrinsic instability, varying side effects associated with the delivery systems, and continuous em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6863ea5db0683946fea2335c183b31b
https://doi.org/10.1101/2022.05.12.491597
https://doi.org/10.1101/2022.05.12.491597
Autor:
Jiali Yang, Jiaojiao Sun, Jiafeng Zhu, Yaran Du, Yiling Tan, Lixiang Wei, Yang Zhao, Qiangbo Hou, Yan Zhang, Zhenhua Sun, Chijian Zuo
Although proteolysis targeting chimera (PROTAC) technology that hijacking the ubiquitin-proteasome system (UPS) to artificially degrade protein is an emerging promising technology for many undruggable targets, it still faces several challenges, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156a0ec418b8f7f9d09cfae7012eff1c
https://doi.org/10.1101/2022.04.22.489232
https://doi.org/10.1101/2022.04.22.489232
Autor:
Lixiang Wei, Andreas Bechthold, Ke Huang, Jiali Yang, Jiafeng Zhu, Zhenbo Tong, Mengting Zhai, Qiangbo Hou, Jiaojiao Sun, Sun Zhenhua, Chijian Zuo, Na Li, Linpeng Wu, Yiling Tan, Yaran Du, Yiyun Chen
The application of mRNA as a novel kind of vaccine has been proved recently, due to the emergence use authorization (EUA) by FDA for the two COVID-19 mRNA vaccines developed by Moderna and BioNTech. Both of the two vaccines are based on canonical lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be2fd598bfa59900fab3991f790df11
https://doi.org/10.1101/2021.11.01.466725
https://doi.org/10.1101/2021.11.01.466725