Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Qiang-Long You"'
Autor:
Zi-Yang Liu, Yuan-Quan Li, Die-Lin Wang, Ying Wang, Wan-Ting Qiu, Yu-Yang Qiu, He-Lin Zhang, Qiang-Long You, Shi-min Liu, Qiu-Ni Liang, Er-Jian Wu, Bing-Jie Hu, Xiang-Dong Sun
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Human patients often experience an episode of serious seizure activity, such as status epilepticus (SE), prior to the onset of temporal lobe epilepsy (TLE), suggesting that SE can trigger the development of epilepsy. Yet, the unde
Externí odkaz:
https://doaj.org/article/e208833a4391498a9b5dd818bf681600
Autor:
Jie Huang, Yan-Yan Zhang, Yu-Yang Qiu, Shan Yao, Wan-Ting Qiu, Jin-Lin Peng, Yuan-Quan Li, Qiang-Long You, Cui-Hong Wu, Er-Jian Wu, Jin Wang, Yan-Ling Zhou, Yu-Ping Ning, Hong-Sheng Wang, Wen-Bing Chen, Bing-Jie Hu, Youtan Liu, Xiang-Dong Sun
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113905- (2024)
Summary: Motivation-driven mating is a basic affair for the maintenance of species. However, the underlying molecular mechanisms that control mating motivation are not fully understood. Here, we report that NRG1-ErbB4 signaling in the medial amygdala
Externí odkaz:
https://doaj.org/article/61d914530c4a4f569396c49faeeb745c
Autor:
Feng Gao, Jie Huang, Guo-Bin Huang, Qiang-Long You, Shan Yao, Shen-Ting Zhao, Jian Liu, Cui-Hong Wu, Gui-Fu Chen, Shi-Min Liu, Zongyan Yu, Yan-Ling Zhou, Yu-Ping Ning, Shenquan Liu, Bing-Jie Hu, Xiang-Dong Sun
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Chronic pain can cause both hyperalgesia and anxiety symptoms. However, how the two components are encoded in the brain remains unclear. The prelimbic cortex (PrL), a critical brain region for both nociceptive and emotional modulations, serves as an
Externí odkaz:
https://doaj.org/article/d3f04cad1c8e4cd585eb54e45f1c69a6
Autor:
Jin Wang, Jie Huang, Shan Yao, Jia-Hui Wu, Hui-Bin Li, Feng Gao, Ying Wang, Guo-Bin Huang, Qiang-Long You, Jianhua Li, Xiaohui Chen, Xiang-Dong Sun
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background The ketogenic diet (KD)has been considered an effective treatment for epilepsy, whereas its underlying mechanisms remain obscure. We have previously reported that the KD feeding increased Neuregulin 1 (NRG1) expression in the hipp
Externí odkaz:
https://doaj.org/article/cdf6ffd71b0940b18bae8a17ea04cd55
Autor:
Qian Wang, Ying Kong, Ding-Yu Wu, Ji-Hong Liu, Wei Jie, Qiang-Long You, Lang Huang, Jian Hu, Huai-De Chu, Feng Gao, Neng-Yuan Hu, Zhou-Cai Luo, Xiao-Wen Li, Shu-Ji Li, Zhao-Fa Wu, Yu-Long Li, Jian-Ming Yang, Tian-Ming Gao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Astrocytes contribute to autism spectrum disorder (ASD) pathophysiology. Here, the authors show that IP3R2 conditional KO mice show ASD-like behaviours and identify astrocyte-derived ATP as a modulator of these behaviours in mice.
Externí odkaz:
https://doaj.org/article/8bdbbf173fa34c22af105a449a7b98e1
Autor:
Qiang-long You, Zhou-cai Luo, Zheng-yi Luo, Ying Kong, Ze-lin Li, Jian-ming Yang, Xiao-wen Li, Tian-ming Gao
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Thalamic reticular nucleus (TRN) is a group of inhibitory neurons surrounding the thalamus. Due to its important role in sensory information processing, TRN is considered as the target nucleus for the pathophysiological investigation of schi
Externí odkaz:
https://doaj.org/article/63095103f4354a209ea4fe744e47b6ba
Autor:
Ji-Hong Liu, Qian Wang, Qiang-Long You, Ze-Lin Li, Neng-Yuan Hu, Yan Wang, Zeng-Lin Jin, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Xin-Hong Zhu, Yi-Fan Dai, Jiang-Ping Xu, Xiao-Chun Bai, Tian-Ming Gao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Acute administration of EPA impairs learning and memory and hippocampal LTP in mice that was mediated through enhancing GABAergic transmission via the 5-HT6R. DHA can prevent EPA-induced impairments at a ratio of EPA to DHA similar to that in marine
Externí odkaz:
https://doaj.org/article/5edff60ffe5c4a1aa0e972347df5b449
Autor:
Wen-Jun Zou, Yun-Long Song, Min-Yi Wu, Xiang-Tian Chen, Qiang-Long You, Qian Yang, Zheng-Yi Luo, Lang Huang, Yin Kong, Jing Feng, Dong-Xiang Fang, Xiao-Wen Li, Jian-Ming Yang, Lin Mei, Tian-Ming Gao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Serotonin is important in depression-like behavior. Here the authors show that dorsal raphe neurons that project to the ventral tegmental area are involved in regulating stress responses in mice.
Externí odkaz:
https://doaj.org/article/4890dfbc60724608bc8878e7391e8318
Autor:
Tian-Ming Gao, Zheng-Yi Luo, Xiao-Wen Li, Zhou-Cai Luo, Jian-Ming Yang, Ze-Lin Li, Qiang-Long You, Ying Kong
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Translational Psychiatry
Translational Psychiatry
Thalamic reticular nucleus (TRN) is a group of inhibitory neurons surrounding the thalamus. Due to its important role in sensory information processing, TRN is considered as the target nucleus for the pathophysiological investigation of schizophrenia
Autor:
Ze-Lin Li, Ji-Hong Liu, Xin-Hong Zhu, Qiang-Long You, Xiaochun Bai, Neng-Yuan Hu, Yan Wang, Jian-Ming Yang, Jiang-Ping Xu, Shu-Ji Li, Zeng-Lin Jin, Tian-Ming Gao, Yifan Dai, Qian Wang, Xiao-Wen Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Eicosapentaenoic acid (EPA), an omega-3 fatty acid, has been widely used to prevent cardiovascular disease (CVD) and treat brain diseases alone or in combination with docosahexaenoic acid (DHA). However, the impact of EPA and DHA supplementation on n