Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Qiang, You"'
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e38951- (2024)
Recent research has highlighted the therapeutic potential of citrus-derived dietary 5,6,7,4′-tetramethoxyflavone (TMF) against HeLa cancer. Our study aims to elucidate its mechanisms of action through proteomics analysis, network pharmacology, and
Externí odkaz:
https://doaj.org/article/e510e68c2e6b40f38496c44b35532dee
Autor:
Qiang You, Enze Qu, Kaining Zeng, Jianrong Liu, Qing Yang, Hui Tang, Xiao Feng, Jia Yao, Xinru Huang, Tong Zhang, Binsheng Fu, Hua Li, Hui Zhao, Jun Zheng, Shuhong Yi, Yang Yang, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 16, Pp 1993-1995 (2024)
Externí odkaz:
https://doaj.org/article/f517746c9b614955803ce4dc8eb0a17e
Autor:
Haitian Chen, Wen Yin, Kang Yao, Jinliang Liang, Jianye Cai, Xin Sui, Xuegang Zhao, Jiebin Zhang, Jiaqi Xiao, Rong Li, Qiuli Liu, Jia Yao, Guohua You, Yasong Liu, Chenhao Jiang, Xiaotong Qiu, Tingting Wang, Qiang You, Yingcai Zhang, Mo Yang, Jun Zheng, Zong Dai, Yang Yang
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Hepatic ischemia‐reperfusion injury (HIRI) is a prevalent issue during liver resection and transplantation, with currently no cure or FDA‐approved therapy. A promising drug, Cyclosporin A (CsA), ameliorates HIRI by maintaining mitochondr
Externí odkaz:
https://doaj.org/article/fcfcbcb4104445b799ce1c3f46e97ee0
Autor:
Chao Hu, Mengjing Li, Yongzhen Chen, Wei Cheng, Haining Wang, Yiming Zhou, Fengmeng Teng, Tao Ling, Jinshun Pan, Haozhe Xu, Yanan Zheng, Guozhong Ji, Ting Zhao, Qiang You
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The cytoplasmic pattern recognition receptor, absent in melanoma 2 (AIM2), detects cytosolic DNA, activating the inflammasome and resulting in pro-inflammatory cytokine production and pyroptotic cell death. Recent research has illuminated AI
Externí odkaz:
https://doaj.org/article/803da7ca9976418f8c105dd155031067
Autor:
Xiaoming Bai, Jiaofang Shao, Tinghong Duan, Xue Liu, Min Wang, Xuanya Li, Qiang You, Zhiyuan Zhang, Jinshun Pan
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Cancer-associated fibroblasts (CAFs) are critically involved in tumor progression by maintaining extracellular mesenchyma (ECM) production and improving tumor development. Cyclooxygenase-2 (COX-2) has been proved to promote ECM fo
Externí odkaz:
https://doaj.org/article/e1abfadcd8dd4652b60998d6ed8e1d67
Autor:
Haining Wang, Wei Cheng, Ping Hu, Tao Ling, Chao Hu, Yongzhen Chen, Yanan Zheng, Junqi Wang, Ting Zhao, Qiang You
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, with the potential to progress to non-alcoholic steatohepatitis (NASH), cirrhosis, and even hepatocellular carcinoma. Given the absence of effectiv
Externí odkaz:
https://doaj.org/article/8352668ff03a4e0ea905e2cb721a3140
Autor:
Qian Peng, Jialu Qiao, Weiling Li, Qiang You, Song Hu, Yuchen Liu, Wei Liu, Kanghong Hu, Binlian Sun
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21307- (2023)
N6-methyladenosine (m6A) methylation of human immunodeficiency virus type 1 (HIV-1) RNA regulates viral replication, and the m6A of host RNA is affected by HIV-1 infection, but its global pattern and function are still unclear. In this study, we repo
Externí odkaz:
https://doaj.org/article/69a2f92ecdba450b9ad613cf37c2ff44
Autor:
Jing Guo, Donglin Sun, Junwei Zhang, Jie Guo, Zhenpeng Wu, Yongzhen Chen, Yujie Xu, Desheng Zhou, Yachao Cui, Qi Mo, Yingchang Li, Ting Zhao, Qiang You
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5212-5227 (2023)
E3 ubiquitin ligases (E3s) play a pivotal role in regulating the specificity of protein ubiquitination, and their significant functions as regulators of immune responses against tumors are attracting considerable interest. RBCK1—an RBR E3 ligase—
Externí odkaz:
https://doaj.org/article/648370b4d0fa43eeb4252a71584033b7
Publikováno v:
The Astrophysical Journal, Vol 968, Iss 2, p 105 (2024)
We derive the initial spin period distribution of neutron stars by studying the population of young pulsars associated with supernova remnants. Our hierarchical Bayesian approach accounts for the measurement uncertainties of individual observations a
Externí odkaz:
https://doaj.org/article/7ece7046fd5a45f0927a9e0180355694
Publikováno v:
The Astrophysical Journal, Vol 962, Iss 1, p 80 (2024)
Spin period distribution provides important clues to understand the formation of millisecond pulsars (MSPs). To uncover the intrinsic period distribution, we analyze three samples of radio MSPs in the Galactic field and globular clusters. The selecti
Externí odkaz:
https://doaj.org/article/beef496584fd44d09591bc848234bcf5