Výsledky vyhledávání - "Qiande Zhang"

Akademický článek

Polyporus Polysaccharide Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Suppressing Myofibroblast Differentiation via TGF-β/Smad2/3 Pathway

Autor: Jintao Jiang, Fang Wang, Aishu Luo, Shiyu Lin, Xiaoke Feng, Wei Yan, Yumeng Shi, Qian Zhang, Xin Gu, Guoliang Cui, Jianan Wang, Lei Wang, Qiande Zhang, Wenfeng Tan

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

Pulmonary fibrosis is a major cause of morbidity and mortality in systemic sclerosis (SSc) with no effective medication. Polyporus polysaccharide (PPS), extracted from Chinese herbs, has immune regulation, anticancer, antioxidant and antiinflammatory

Externí odkaz: https://doaj.org/article/df20d9d13d0d4eb3911986e5e7948619

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Akademický článek

The Bone Marrow Edema Links to an Osteoclastic Environment and Precedes Synovitis During the Development of Collagen Induced Arthritis

Autor: Fang Wang, Aishu Luo, Wenhua Xuan, Liang Qi, Qing Wu, Ke Gan, Qiande Zhang, Miaojia Zhang, Wenfeng Tan

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Objectives: To determine the relationship between bone marrow edema (BME), synovitis, and bone erosion longitudinally using a collagen induced arthritis mice (CIA) model and to explore the potential pathogenic role of BME in bone erosion.Methods: CIA

Externí odkaz: https://doaj.org/article/a5b77b026eec420b94c45e5d58e214db

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The Bone Marrow Edema Links to an Osteoclastic Environment and Precedes Synovitis During the Development of Collagen Induced Arthritis

Autor: Qing Wu, Wenhua Xuan, Fang Wang, Aishu Luo, Wenfeng Tan, Ke Gan, Liang Qi, Qiande Zhang, Miaojia Zhang

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b4370075188b7a5b6a1f54a4dc7d2
http://europepmc.org/articles/PMC6491763

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Iguratimod (T-614) suppresses RANKL-induced osteoclast differentiation and migration in RAW264.7 cells via NF-κB and MAPK pathways

Autor: Fang Wang, Wenfeng Tan, Ke Gan, Xiaoke Feng, Qiande Zhang, Miaojia Zhang, Leilei Yang, Lingxiao Xu

Publikováno v: International Immunopharmacology. 35:294-300

Introduction Iguratimod (T-614) has been confirmed as a highly efficacious and safe novel disease-modifying anti-rheumatic drug (DMARD) for rheumatoid arthritis therapy in China and Japan due to its potent anti-inflammation effect. Here, we investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dca390c613700afe1a7920dbad323d
https://doi.org/10.1016/j.intimp.2016.03.038

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THU0079 Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis

Autor: Qiande Zhang, Wenhua Xuan, Jie Qian, Miaojia Zhang, W. Tan, Qin Wu, Pengfei Zhao, Xinchen Sun, Rui Liu, Lingxiao Xu, Fuqiang Wang, Nan Che, Yingyi Wang

Publikováno v: THURSDAY, 14 JUNE 2018.

Background We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates closely with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD towards promoting joint destruction re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d964683db40a54ce712efd202757cf0
https://doi.org/10.1136/annrheumdis-2018-eular.3379

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Celastrol attenuates bone erosion in collagen-Induced arthritis mice and inhibits osteoclast differentiation and function in RANKL-induced RAW264.7

Autor: Ke Gan, Fang Wang, Xiaoke Feng, Qiande Zhang, Miaojia Zhang, Wenfeng Tan, Lingxiao Xu

Publikováno v: International immunopharmacology. 24(2)

Recently, the traditional Chinese medicine Tripterygium wilfordii Hook f (TwHF) of the Celastraceae family has attracted increasing attention for its potential therapeutic application in patients with rheumatoid arthritis (RA). It is well accepted th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677b2a5d77ac6c22fce6def5a270f582
https://pubmed.ncbi.nlm.nih.gov/25529994

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High adiponectin and adiponectin receptor 1 expression in synovial fluids and synovial tissues of patients with rheumatoid arthritis

Autor: Qiande Zhang, Shaoheng He, Wenfeng Tan, Miaojia Zhang, Dunming Guo, Fang Wang

Publikováno v: Seminars in arthritis and rheumatism. 38(6)

Objectives The major objectives of this article are first to measure the levels of expression of adiponectin and its 2 receptors (adipoR1 and adipoR2) in the peripheral blood mononuclear cells and in the synovial compartment of rheumatoid arthritis (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00586cccb897be0b23f442949844121
https://pubmed.ncbi.nlm.nih.gov/18395775

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FRI0367 Celastrol Inhibits Osteoclastogenesis and Bone Resorption in Rankl-Induced Raw264.7 via Nf-κB and MAPK Pathways and Attenuates Bone Erosion in Collagen-Induced Arthritis

Autor: W. Tan, Qiande Zhang, L P Xu, Miaojia Zhang, K. Gan, Fuqiang Wang, Xingmei Feng

Publikováno v: Annals of the Rheumatic Diseases. 73:520.1-520

Background Celastrus have been long used to treat various inflammatory disorders including Rheumatoid arthritis (RA), SLE and Ankylosing Spondylitis in China. Celastrol is one of the main bioactive component of Celastrus. Previous study have reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be09dd5adef8e0b913a3b28b64ba8c06
https://doi.org/10.1136/annrheumdis-2014-eular.3939

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