Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Qian-Lin Hao"'
Autor:
Mary A. Price, Qian Lin Hao, Grace Huang, Ineavely Baez, Mercy Kagoda, Nathan R. Wall, Eva Sahakian, Nicholas R. Galloway, Terry Ann M. Milford, Ewa Zielinska, Abigail Benitez, Jaqueline W. Rogerio, Yazmar Sevilla, Sinisa Dovat, Kimberly J. Payne, Lora Barsky, Yasmin Khan Parrish
Publikováno v:
The Journal of Immunology. 182:4255-4266
IL-7 is critical for B cell production in adult mice; however, its role in human B lymphopoiesis is controversial. One challenge was the inability to differentiate human cord blood (CB) or adult bone marrow (BM) hematopoietic stem cells (HSCs) withou
Autor:
Qian-Lin Hao, Aswathi A. George, Judy Zhu, Lora Barsky, Ewa Zielinska, Xiuli Wang, Mary Price, Shundi Ge, Gay M. Crooks
Publikováno v:
Blood. 111:1318-1326
The identity and lineage potential of the cells that initiate thymopoiesis remain controversial. The goal of these studies was to determine, at a clonal level, the immunophenotype and differentiation pathways of the earliest progenitors in human thym
Autor:
Te-Cheng Pan1, Qian-lin Hao1, Ting-Ting Yamin1, Pei-Hua Dai1, Bao-Sheng Chen1, Shiow-Ling Chen1, Kroon, Paulus A.1, Yu-Sheng Chao1
Publikováno v:
European Journal of Biochemistry. 12/30/87, Vol. 170 Issue 1/2, p99-104. 6p.
Publikováno v:
Blood. 101:4201-4208
Rodent bone marrow cells can contribute to liver. If these findings are applicable to humans, marrow stem cells could theoretically be harvested from a patient and used to repair his/her damaged liver. To explore this potential, CD34+ or highly purif
Publikováno v:
Blood. 97:3683-3690
The earliest stages of lymphoid commitment from human pluripotent hematopoietic stem cells have not been defined. A clonogenic subpopulation of CD34(+)CD38(-) cord blood cells were identified that expressed high levels of the CD7 antigen and possesse
Publikováno v:
The Journal of Immunology. 165:2382-2389
The effect of IL-3 on the B lymphoid potential of human hemopoietic stem cells is controversial. Murine studies suggest that B cell differentiation from uncommitted progenitors is completely prevented after short-term exposure to IL-3. We studied B l
Publikováno v:
Blood. 91:4145-4151
Human hematopoietic stem cells are pluripotent, ie, capable of producing both lymphoid and myeloid progeny, and are therefore used for transplantation and gene therapy. An in vitro culture system was developed to study the multi-lineage developmental
Publikováno v:
Blood. 91:4145-4151
Human hematopoietic stem cells are pluripotent, ie, capable of producing both lymphoid and myeloid progeny, and are therefore used for transplantation and gene therapy. An in vitro culture system was developed to study the multi-lineage developmental
Publikováno v:
Blood. 86:3745-3753
We present cell cycling and functional evidence that the CD34+CD38- immunophenotype can be used to define a rare and primitive subpopulation of progenitor cells in umbilical cord blood. CD34+CD38- cells comprise 0.05% +/- 0.08% of the mononuclear cel
Publikováno v:
Human Gene Therapy. 6:873-880
Gene therapy is a potential treatment for hemophilia, wherein cells transduced with a normal factor IX gene could provide a continuous in vivo source of circulating factor IX. In this study, we examined the potential use of hematopoietic cells as a t