Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Qian-Hang Shao"'
Autor:
Xiao-Ling Zhang, Zhen-Zhen Wang, Qian-Hang Shao, Zhao Zhang, Lin Li, Zhen-Yu Guo, Hong-Mei Sun, Yi Zhang, Nai-Hong Chen
Publikováno v:
Brain Research Bulletin, Vol 209, Iss , Pp 110926- (2024)
Externí odkaz:
https://doaj.org/article/4c5e9cbaf3ed4d06a2c2bdc3baf7abf9
Autor:
Cong-Yuan Xia, Ning-Ning Zhang, Hong Jiang, Yu-Xia Lou, Qian Ren, Xiao-Ling Zhang, Peng-Fei Yang, Qian-Hang Shao, Hao-Yu Zhu, Jiang-Fan Wan, Ya-Ni Zhang, Fang-Fang Li, Xu Yan, Shi-Feng Chu, Yi Zhang, Zhen-Zhen Wang, Nai-Hong Chen
Publikováno v:
Journal of Pharmacy and Pharmacology. 75:686-692
Objectives Fluoxetine has been used as the first line for the therapy of depression. However, lack of therapeutic efficacy and time lag still limit the application of fluoxetine. Gap junction dysfunction is a potentially novel pathogenic mechanism fo
Publikováno v:
Acta Pharmacologica Sinica. 43:2253-2266
Neuroinflammation is closely related to the pathogenesis of neurodegenerative diseases. Activation of microglia, the resident immune cells in CNS, induces inflammatory responses, resulting in the release of neurotoxic molecules, which favors neuronal
Autor:
Shuo Wang, Nai-Hong Chen, Xiao-ling Zhang, Ying Chen, Yu-He Yuan, Fang-fang Li, Qian-Hang Shao
Publikováno v:
Acta Pharmacologica Sinica
Parkinson’s disease (PD) is a multifactorial disorder characterized by progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and the presence of Lewy bodies (LBs) consisting of misfolded α-synuclein protein. Th
Autor:
Zhao Zhang, Zhen-Zhen Wang, Yi Zhang, Zhen-Yu Guo, Hong-Mei Sun, Xiao-ling Zhang, Nai-Hong Chen, Lin Li, Qian-Hang Shao
Publikováno v:
Brain Research Bulletin. 146:228-236
Deletions or some mutations in the gene encoding the multifunctional protein, DJ-1, have been considered to be linked with autosomal recessive early onset Parkinson's disease (PD). Current emerging evidence suggests that DJ-1 is involved in the prote
Autor:
Shan-ying Peng, Qian-Hang Shao, Yu-He Yuan, Wen-Fen Yan, Zhao Zhang, Ying-Li Cao, Nai-Hong Chen, Kai-Li Ma
Publikováno v:
Neuropharmacology. 144:388-399
Parkinson's disease (PD) is a multi-factorial neurodegenerative disease. Abnormal α-synuclein protein aggregate and sustained microglia activation contribute to the pathogenic processes of PD. However, the relationship between α-synuclein and micro
Autor:
Ying Chen, Shuo Wang, Yu-He Yuan, Qiu-Shuang Zhang, Hong-Bo Wang, Qian-Hang Shao, Nai-Hong Chen
Publikováno v:
Acta Pharmacol Sin
Olfactory bulb, as one of sensory organs opening to the outside, is susceptible to toxic environment and easy to deteriorate. Recent studies in Parkinson’s disease (PD) patients and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1379a68ea51e91244b8b817bfeaf44
https://europepmc.org/articles/PMC6786401/
https://europepmc.org/articles/PMC6786401/
Autor:
Ying Chen, Nai-Hong Chen, Yu-He Yuan, Qian-Hang Shao, Jiangong Shi, Xiao-ling Zhang, Cheng-Gen Zhu
Publikováno v:
Molecular immunology. 101
Publikováno v:
Brain research bulletin. 140
Parkinson's disease (PD) is a progressive degenerative disease of the nervous system, which is characterized by movement disorders, such as static tremor, rigidity, and bradykinesia in advanced patients. Gastrointestinal (GI) dysfunction, such as gas
Autor:
Nai-Hong Chen, Ying Chen, Yu-He Yuan, Qian-Hang Shao, Cheng-Gen Zhu, Jiangong Shi, Xiao-ling Zhang
Publikováno v:
Molecular immunology. 99
20C, a novel bibenzyl compound, is isolated from Gastrodia elata. In our previous study, 20C showed protective effects on tunicamycin-induced endoplasmic reticulum stress, rotenone-induced apoptosis and rotenone-induced oxidative damage. However, the