Tiered analytics for purity assessment of macrocyclic peptides in drug discovery: Analytical consideration and method development.

Autor: Qian Cutrone JJ; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA. Electronic address: jingfang.cutrone@bms.com., Huang XS; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Kozlowski ES; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Bao Y; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Wang Y; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Poronsky CS; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Drexler DM; Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Tymiak AA; Bristol-Myers Squibb Co., Research and Development, P.O. Box 4000, Princeton, NJ 08543, USA.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2017 May 10; Vol. 138, pp. 166-174. Date of Electronic Publication: 2017 Feb 03.