Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Qian‐Xing Zhuang"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Central orexinergic system deficiency results in cataplexy, a motor deficit characterized with a sudden loss of muscle tone, highlighting a direct modulatory role of orexin in motor control. However, the neural mechanisms underlying the regulation of
Externí odkaz:
https://doaj.org/article/9871ca8e77ec400bbb57bdff0703c373
Publikováno v:
Neurosignals, Vol 21, Iss 3-4, Pp 174-183 (2012)
The superior vestibular nucleus (SVN), which holds a key position in vestibulo-ocular reflexes and nystagmus, receives direct hypothalamic histaminergic innervations. By using rat brainstem slice preparations and extracellular unitary recordings, we
Externí odkaz:
https://doaj.org/article/7d62a467783344aca38a2a5bd01fbdb2
Publikováno v:
Journal of Affective Disorders. 335:195-203
Autor:
Zeng‐Xin Qi, Kang‐Li Shen, Jian‐Ya Peng, Xiu‐Juan Fan, Hui‐Wei Huang, Jian‐Lan Jiang, Jian‐Hua Lu, Xiao‐Qin Wang, Xiao‐Xia Fang, Liang Chen, Qian‐Xing Zhuang
Publikováno v:
British Journal of Pharmacology. 180:1379-1407
Parvalbumin (PV)-positive neurons are type of neurons in lateral globus pallidus (LGP) that play an important role in motor control. The present study investigated the effect of histamine on LGPHistamine level and histaminergic innervation in LGP wer
Autor:
Jian-Ya Peng, Zeng-Xin Qi, Qi Yan, Xiu-Juan Fan, Kang-Li Shen, Hui-Wei Huang, Jian-Hua Lu, Xiao-Qin Wang, Xiao-Xia Fang, Liming Mao, Jianguang Ni, Liang Chen, Qian-Xing Zhuang
Publikováno v:
Proceedings of the National Academy of Sciences. 120
In Parkinson’s disease (PD), reduced dopamine levels in the basal ganglia have been associated with altered neuronal firing and motor dysfunction. It remains unclear whether the altered firing rate or pattern of basal ganglia neurons leads to parki
Autor:
Jian-Ya Peng, Kang-Li Shen, Xiu-Juan Fan, Zeng-Xin Qi, Hui-Wei Huang, Jian-Lan Jiang, Jian-Hua Lu, Xiao-Qin Wang, Xiao-Xia Fang, Wang-Rui Yuan, Qiao-Xuan Deng, Shu Chen, Liang Chen, Qian-Xing Zhuang
Publikováno v:
Molecular neurobiology. 60(1)
The dorsolateral striatum (DLS) is the critical neural substrate that plays a role in motor control and motor learning. Our past study revealed a direct histaminergic projection from the tuberomammillary nucleus (TMN) of the hypothalamus to the rat s
Autor:
Shi-Yu Peng, Shu-Tao Xie, Jing-Ning Zhu, Jian-Jun Wang, Tian-Yu Ma, Qi-Peng Zhang, Bin Li, Xiao-Yang Zhang, Qian-Xiao Li, Li-Ping Shen, Qian-Xing Zhuang, Ming-Run Shi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Anxiety disorders and obsessive-compulsive disorder (OCD) are highly prevalent and debilitating psychiatric disorders commonly co-occurring in our stressful modern life. Yet the common effective therapeutic target is still unknown. Here
Autor:
Xiao-Yang Zhang, Jian-Jun Wang, Guang-Ying Li, Hong-Zhao Li, Chang-Zheng Zhang, Qian-Xing Zhuang, Kang Xi, Jing-Ning Zhu, Bin Li
Publikováno v:
Journal of Clinical Investigation. 128:5413-5427
The subthalamic nucleus (STN) is an effective therapeutic target for deep brain stimulation (DBS) for Parkinson's disease (PD), and histamine levels are elevated in the basal ganglia in PD patients. However, the effect of endogenous histaminergic mod
Autor:
Guan-Yi, Wu, Qian-Xing, Zhuang, Xiao-Yang, Zhang, Hong-Zhao, Li, Jian-Jun, Wang, Jing-Ning, Zhu
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 71(6)
Spinal α-motoneurons directly innervate skeletal muscles and function as the final common path for movement and behavior. The processes that determine the excitability of motoneurons are critical for the execution of motor behavior. In fact, it has
Autor:
Xu-Juan Lu, Han-Ting Xu, Jian-Jun Wang, Qian-Xing Zhuang, Wing-Ho Yung, Jing-Ning Zhu, Bin Li
Publikováno v:
Molecular Neurobiology. 55:8059-8070
The central histaminergic nervous system, originating from the tuberomammillary nucleus (TMN) of the hypothalamus, widely innervates almost the whole brain, including the basal ganglia. Intriguingly, the histaminergic system is altered in parkinsonia