Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver

Autor: Sojoodi, Mozhdeh, Erstad, Derek J., Barrett, Stephen C., Salloum, Shadi, Zhu, Shijia, Qian, Tongqi, Colon, Selene, Gale, Eric M., Jordan, Veronica Clavijo, Wang, Yongtao, Li, Shen, Ataeinia, Bahar, Jalilifiroozinezhad, Sasan, Lanuti, Michael, Zukerberg, Lawrence, Caravan, Peter, Hoshida, Yujin, Chung, Raymond T., Bhave, Gautam, Lauer, Georg M., Fuchs, Bryan C., Tanabe, Kenneth K.

Publikováno v: In Cellular and Molecular Gastroenterology and Hepatology 2022 13(5):1483-1509

Omics‐derived hepatocellular carcinoma risk biomarkers for precision care of chronic liver diseases.

Autor: Fujiwara, Naoto^1,2 (AUTHOR) naoto.fujiwara@utsouthwestern.edu, Qian, Tongqi¹ (AUTHOR), Koneru, Bhuvaneswari¹ (AUTHOR), Hoshida, Yujin¹ (AUTHOR) yujin.hoshida@utsouthwestern.edu

Publikováno v: Hepatology Research. Jul2020, Vol. 50 Issue 7, p817-830. 14p.

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A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery

Autor: Crouchet, Emilie, Bandiera, Simonetta, Fujiwara, Naoto, Li, Shen, El Saghire, Hussein, Fernández-Vaquero, Mirian, Riedl, Tobias, Sun, Xiaochen, Hirschfield, Hadassa, Jühling, Frank, Zhu, Shijia, Roehlen, Natascha, Ponsolles, Clara, Heydmann, Laura, Saviano, Antonio, Qian, Tongqi, Venkatesh, Anu, Lupberger, Joachim, Verrier, Eloi R., Sojoodi, Mozhdeh, Oudot, Marine A., Duong, François H. T., Masia, Ricard, Wei, Lan, Thumann, Christine, Durand, Sarah C., González-Motos, Victor, Heide, Danijela, Hetzer, Jenny, Nakagawa, Shigeki, Ono, Atsushi, Song, Won-Min, Higashi, Takaaki, Sanchez, Roberto, Kim, Rosa S., Bian, C. Billie, Kiani, Karun, Croonenborghs, Tom, Subramanian, Aravind, Chung, Raymond T., Straub, Beate K., Schuppan, Detlef, Ankavay, Maliki, Cocquerel, Laurence, Schaeffer, Evelyne, Goossens, Nicolas, Koh, Anna P., Mahajan, Milind, Nair, Venugopalan D., Gunasekaran, Ganesh, Schwartz, Myron E., Bardeesy, Nabeel, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Felli, Emanuele, Pessaux, Patrick, Tanabe, Kenneth K., Heikenwälder, Mathias, Schuster, Catherine, Pochet, Nathalie, Zeisel, Mirjam B., Fuchs, Bryan C., Hoshida, Yujin, Baumert, Thomas F.

Publikováno v: Nature Communications
Nature Communications, 2021, 12 (1), pp.5525. ⟨10.1038/s41467-021-25468-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5525. ⟨10.1038/s41467-021-25468-9⟩

Chronic liver disease and hepatocellular carcinoma (HCC) are life-threatening diseases with limited treatment options. The lack of clinically relevant/tractable experimental models hampers therapeutic discovery. Here, we develop a simple and robust h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f0c52e28e4771781df271af268b8f8f4
https://hal.science/hal-03395220/document