Zobrazeno 1 - 10
of 453
pro vyhledávání: '"QiXin Chen"'
Autor:
Jiangjie Chen, Jinyang Chen, Chao Yu, Kaishun Xia, Biao Yang, Ronghao Wang, Yi Li, Kesi Shi, Yuang Zhang, Haibin Xu, Xuesong Zhang, Jingkai Wang, Qixin Chen, Chengzhen Liang
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1042-1057 (2025)
Spinal cord injuries impose a notably economic burden on society, mainly because of the severe after-effects they cause. Despite the ongoing development of various therapies for spinal cord injuries, their effectiveness remains unsatisfactory. Howeve
Externí odkaz:
https://doaj.org/article/c9f2d0e5ff044a6baa11ee57837e106e
Autor:
Lingxiu Kong, Qingjie Bai, Cuicui Li, Qiqin Wang, Yanfeng Wang, Xintian Shao, Yongchun Wei, Jiarao Sun, Zhenjie Yu, Junling Yin, Bin Shi, Hongbao Fang, Xiaoyuan Chen, Qixin Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Lipid droplets (LDs) feature a unique monolayer lipid membrane that has not been extensively studied due to the lack of suitable molecular probes that are able to distinguish this membrane from the LD lipid core. In this work, we present a t
Externí odkaz:
https://doaj.org/article/8932fbf85a9a4ece832470788a232c23
Publikováno v:
Surgeries, Vol 5, Iss 3, Pp 619-626 (2024)
Background: Skeleton involvement is one of the most significant aspects of Gaucher disease (GD). However, the treatment for spinal involvement in GD among patients undergoing enzyme replacement therapy (ERT) is poorly characterized. We present a case
Externí odkaz:
https://doaj.org/article/3183cbbab74f46d0bfe98b395ccf0f56
Autor:
Ting Sun, Huanxin Zhao, Luyao Hu, Xintian Shao, Zhiyuan Lu, Yuli Wang, Peixue Ling, Yubo Li, Kewu Zeng, Qixin Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2428-2446 (2024)
The visualization of drugs in living systems has become key techniques in modern therapeutics. Recent advancements in optical imaging technologies and molecular design strategies have revolutionized drug visualization. At the subcellular level, super
Externí odkaz:
https://doaj.org/article/fc6580a181d341c8bb684c82b6447e67
Publikováno v:
Exploration, Vol 4, Iss 5, Pp n/a-n/a (2024)
Abstract Super‐resolution imaging techniques, such as structured illumination microscopy (SIM), have enabled researchers to obtain nanoscale organelle‐level outputs in living systems, but they impose additional stringent requirements on fluoresce
Externí odkaz:
https://doaj.org/article/ebb4440dbe4546df9f40b9f67d66f010
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1864-1877 (2024)
Small molecule drugs play a pivotal role in the arsenal of anticancer pharmacological agents. Nonetheless, their small size poses a challenge when directly visualizing their localization, distribution, mechanism of action (MOA), and target engagement
Externí odkaz:
https://doaj.org/article/125e6d3194264cb2af39a877e9f37566
Autor:
Zhenjie Yu, Huarong Shao, Xintian Shao, Linyan Yu, Yanan Gao, Youxiao Ren, Fei Liu, Caicai Meng, Peixue Ling, Qixin Chen
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 6, Pp 100932- (2024)
Unlike chemosynthetic drugs designed for specific molecular and disease targets, active small-molecule natural products typically have a wide range of bioactivities and multiple targets, necessitating extensive screening and development. To address t
Externí odkaz:
https://doaj.org/article/36206846d27d45bd8c47872afc3d7f87
Publikováno v:
Journal of Modern Power Systems and Clean Energy, Vol 12, Iss 2, Pp 346-358 (2024)
The scale of distributed energy resources is increasing, but imperfect business models and value transmission mechanisms lead to low utilization ratio and poor responsiveness. To address this issue, the concept of cleanness value of distributed energ
Externí odkaz:
https://doaj.org/article/662527189c2848969f43f00328d72a40
Publikováno v:
Energy Reports, Vol 9, Iss , Pp 1149-1159 (2023)
The online interactive workloads and offline batch computing services of Internet data centers (IDCs) have scheduling flexibility. Batch computing tasks with low latency sensitivity and priority can adjust the processing time and provide flexibility
Externí odkaz:
https://doaj.org/article/f6f8e524c4774fffb3e101041bcae6ce
Publikováno v:
Small Structures, Vol 5, Iss 4, Pp n/a-n/a (2024)
Nanostructural contact sites formed by interorganelle membrane contacts, including mitochondria and lysosome contacts (MLC), facilitate the exchange of substances during various life processes. However, existing bioanalytical technologies have yet to
Externí odkaz:
https://doaj.org/article/09dc103257594213a1e4da2d0046aba5