Zobrazeno 1 - 10
of 681
pro vyhledávání: '"QiJun Chen"'
Autor:
Xin Li, Ning Jiang, Qilong Li, Kexin Zheng, Yiwei Zhang, Xiaoyu Sang, Ying Feng, Ran Chen, Qijun Chen
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Background Artemisinin (ART) is a frontline drug for the treatment of malaria; however, the emergence of ART-resistant Plasmodium strains necessitates increasing ART sensitivity. Given that taurine (TAU) has been shown to have immunomodulato
Externí odkaz:
https://doaj.org/article/23ccdb2afdd14f38a22db1f46fe8e1ae
Publikováno v:
Asian Journal of Surgery, Vol 47, Iss 12, Pp 5381-5383 (2024)
Externí odkaz:
https://doaj.org/article/1f3f1dc28fde44fa9302e6499e2c1c4e
Calcium-binding protein TgpCaBP regulates calcium storage of the zoonotic parasite Toxoplasma gondii
Autor:
Weisong Sun, Ning Jiang, Qilong Li, Yize Liu, Yiwei Zhang, Ran Chen, Ying Feng, Xiaoyu Sang, Shaojun Long, Qijun Chen
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Toxoplasma gondii, the causative parasite of toxoplasmosis, is an apicomplexan parasite that infects warm-blooded mammals. The ability of the calcium-binding proteins (CBPs) to transport large amounts of Ca2+ appears to be critical for the b
Externí odkaz:
https://doaj.org/article/54c014e8ac254c51962589b0bd11f16e
Autor:
Qilong Li, Kunying Lv, Ning Jiang, Tong Liu, Nan Hou, Liying Yu, Yixin Yang, Anni Feng, Yiwei Zhang, Ziwei Su, Xiaoyu Sang, Ying Feng, Ran Chen, Wenyue Xu, Liwang Cui, Yaming Cao, Qijun Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Host immune responses are tightly controlled by various immune factors during infection, and protozoan parasites also manipulate the immune system to evade surveillance, leading to an evolutionary arms race in host‒pathogen interactions; h
Externí odkaz:
https://doaj.org/article/a5e352daacf2414387c93e634bdef90c
Autor:
Xuexia Wen, Yaoqi Fang, Feng Jiang, Yixin Wang, Qijun Chen, Zeliang Chen, Yuhan Wu, Qing Xin, Xiaohu Han, Hua Deng
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35009- (2024)
Bartonella spp. are globally distributed gram-negative facultative intracellular bacteria that infect a wide range of hosts. Rodents are natural reservoirs of many Bartonella species, some of which are also pathogenic to humans. The rapid development
Externí odkaz:
https://doaj.org/article/60235d5631804064a1bf71a6fbfd00e1
Autor:
Junling Li, Yan Zhang, Te Li, Binbin Nie, Fang Qi, Qijun Chen, Tianxing Chen, Yuhang Liu, Gaifen Li, Yubo Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundAn accumulating body of research indicates that the pons is related to the occurrence of depression. Si-Ni-San (SNS) is a well-known Chinese herbal formula that is used to treat depression. Chinese herbal formulae have multiple therapeutic
Externí odkaz:
https://doaj.org/article/cb5493b7583d4b3cb1d8401ed62b7d65
Autor:
Chenghuan Li, Ning Jiang, Yize Liu, Yiwei Zhang, Ran Chen, Ying Feng, Xiaoyu Sang, Qijun Chen
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background The human sortilin protein is an important drug target and detection marker for cancer research. The sortilin from Toxoplasma gondii transports proteins associated with the apical organelles of the parasite. In this study, we aime
Externí odkaz:
https://doaj.org/article/b6eb2f17de884cdc8f7c18349e5c3c5a
Autor:
Kexin Zheng, Qilong Li, Ning Jiang, Yanxin Zhang, Yuxin Zheng, Yiwei Zhang, Ying Feng, Ran Chen, Xiaoyu Sang, Qijun Chen
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTRemodeling the erythrocyte membrane and skeleton by the malarial parasite Plasmodium falciparum is closely associated with intraerythrocytic development. However, the mechanisms underlying this association remain unclear. In this study, we pr
Externí odkaz:
https://doaj.org/article/016deafe445042528b9f0c0512fd01f9
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 6, Pp 1163-1181 (2023)
The biology of Toxoplasma gondii, the causative pathogen of one of the most widespread parasitic diseases (toxoplasmosis), remains poorly understood. Lactate, which is derived from glucose metabolism, is not only an energy source in a variety of orga
Externí odkaz:
https://doaj.org/article/59a27eca0dfc484fb01a02516c08013f
Autor:
Qijun Chen, Lixue Wang, Hui Song, Wen Xing, Junfeng Shi, Yudi Li, Ziqian Wang, Jinlong Chen, Nan Xie, Wenhua Zhao
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19744-19757 (2023)
Abstract Background Colorectal cancer (CRC) is one of the most common tumors in the world. Cholesterol plays an important role in the pathogenesis of tumors. One of the cholesterol transporters, scavenger receptor class B type 1 (SR‐B1), a multi‐
Externí odkaz:
https://doaj.org/article/2a2cc7aac2b745e88970d1b09d70d98a