Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Qi-Yuan Guan"'
Autor:
Shan-Shan Li, Qi-Yuan Guan, Gang Meng, Xiao-Feng Chang, Ji-Wu Wei, Peng Wang, Bin Kang, Jing-Juan Xu, Hong-Yuan Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Better understanding the drug action within cells may extend our knowledge on drug action mechanisms and promote new drugs discovery. Herein, we studied the processes of drug induced chemical changes on proteins and nucleic acids in human br
Externí odkaz:
https://doaj.org/article/9c103e92b70b406c982b341cd8b68ebb
Autor:
Ting-Ting Zhang, Qi-Yuan Guan, Shanshan Li, Pei Song, Jing-Juan Xu, Kai Zhang, Hong-Yuan Chen, Fan Yang, Bin Kang
Publikováno v:
Analytical Chemistry. 89:10239-10247
It is a great challenge to design a drug delivery system with a controlled manner, especially one triggered by an exclusive endogenous disease marker and with an easily tracked release process. Herein, we developed a drug delivery platform of carbon
Publikováno v:
Talanta. 171:190-196
The direct separation and analysis of chiral drugs in the complex matrix systems are meaningful and challenging. As the most common broad-spectrum antibiotic, levofloxacin has a strong antibacterial ability, but its enantiomer, dextrofloxacin can cau
Autor:
Jing-Juan Xu, Xing-Hua Xia, Xiao-Xiao Jiang, Jiang Wang, Jun Hu, Zeng-Qiang Wu, Qi-Yuan Guan, Hong-Yuan Chen
Publikováno v:
Analytical Chemistry. 89:1838-1845
In the work, we showed that the use of nanoemitters (tip dimension1 μm, typically ∼100 nm) could dramatically reduce the nonspecific metal adduction to peptide or protein ions as well as improve the matrix tolerance of electrospray ionization mass
Autor:
Aiping Chen, Jiwu Wei, Jing-Juan Xu, Hong-Yuan Chen, Bin Kang, Li-Bin Zhang, Qi-Yuan Guan, Pan-Ke Zhang, Shanshan Li
Publikováno v:
Chemical Science. 8:1243-1250
Apoptosis and necrosis are distinct cell death processes related to many cellular pathways. In situ, quantitatively and dynamically monitoring such processes may provide vitally important information for cell studies. However, such a method still rem
Autor:
Bin Kang, Yuqi Wang, Deju Ye, Shanshan Li, Hong-Yuan Chen, Mengmeng Zheng, Jing-Juan Xu, Qi-Yuan Guan
Publikováno v:
Chemical Science
Three endogenous biothiols in single cells were simultaneously quantified by plasmonic Raman probes and quantitative principal component analysis (qPCA).
Intracellular biothiols mediate many important physiological and pathological processes. Du
Intracellular biothiols mediate many important physiological and pathological processes. Du
Publikováno v:
Analytical chemistry. 89(15)
We report a multicolor ECL device based on closed bipolar electrode (BPE) for the visualized sensing of prostate-specific antigen (PSA) in human blood serum. As the emission color of concomitant electrochemiluminophores is potential resolved, similar
Autor:
Bin Kang, Peng Wang, Xiaofeng Chang, Shanshan Li, Gang Meng, Jing-Juan Xu, Qi-Yuan Guan, Hong-Yuan Chen, Jiwu Wei
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Better understanding the drug action within cells may extend our knowledge on drug action mechanisms and promote new drugs discovery. Herein, we studied the processes of drug induced chemical changes on proteins and nucleic acids in human breast aden
Publikováno v:
Analytical chemistry. 88(14)
In this work, a synchronized polarization induced electrospray ionization (SPI-ESI) method is developed and applied for the analysis of single-cell samples. In SPI-ESI, periodic alternating current square wave voltage (AC-SWV) is applied to induce th
Autor:
Jun Hu, Xiao-Xiao Jiang, Jiang Wang, Qi-Yuan Guan, Pan-Ke Zhang, Jing-Juan Xu, Hong-Yuan Chen
Publikováno v:
Analytical Chemistry; 7/19/2016, Vol. 88 Issue 14, p7245-7251, 7p