Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Qi-Yu Chen"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Areca nut, the seed of Areca catechu L., is one of the most widely consumed addictive substances in the world after nicotine, ethanol, and caffeine. The major effective constituent of A. catechu, arecoline, has been reported to affect the ce
Externí odkaz:
https://doaj.org/article/18b38400581b49828b9514c60e1b6296
Autor:
Xu‐Hui Li, Wantong Shi, Zhi‐Xia Zhao, Takanori Matsuura, Jing‐Shan Lu, Jingmin Che, Qi‐Yu Chen, Zhaoxiang Zhou, Man Xue, Shun Hao, Fang Xu, Guo‐Qiang Bi, Bong‐Kiun Kaang, Graham L. Collingridge, Min Zhuo
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract The corticostriatal connection plays a crucial role in cognitive, emotional, and motor control. However, the specific roles and synaptic transmissions of corticostriatal connection are less studied, especially the corticostriatal transmissio
Externí odkaz:
https://doaj.org/article/3737e0d224da4191a77ea68ed06b589a
Autor:
Yang Li, Chenhao Li, Qi-Yu Chen, Shun Hao, Jingrui Mao, Wenwen Zhang, Xun Han, Zhao Dong, Ruozhuo Liu, Wenjing Tang, Min Zhuo, Shengyuan Yu, Yinglu Liu
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Recent animal and clinical findings consistently highlight the critical role of calcitonin gene-related peptide (CGRP) in chronic migraine (CM) and related emotional responses. CGRP antibodies and receptor antagonists have been ap
Externí odkaz:
https://doaj.org/article/c582282d862548edb810336215199470
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Adenylyl cyclase 1 (AC1) is a selective subtype of ACs, which is selectively expressed in neurons. The activation of AC1 is activity-dependent, and AC1 plays an important role in cortical excitation that contributes to chronic pain and relat
Externí odkaz:
https://doaj.org/article/e4b921dc7d894528ad2ae91720ad0fb8
Autor:
Xu-Hui Li, Wantong Shi, Qi-Yu Chen, Shun Hao, Hui-Hui Miao, Zhuang Miao, Fang Xu, Guo-Qiang Bi, Min Zhuo
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract The brain consists of the left and right cerebral hemispheres and both are connected by callosal projections. Less is known about the basic mechanism of this cortical-cortical connection and its functional importance. Here we investigate the
Externí odkaz:
https://doaj.org/article/ecfb5715867942a293852372758b9ded
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1072 (2024)
Nitric oxide (NO) is a key diffusible messenger in the mammalian brain. It has been proposed that NO may diffuse in retrograde into presynaptic terminals, contributing to the induction of hippocampal long-term potentiation (LTP). Here, we present nov
Externí odkaz:
https://doaj.org/article/902a3117b91045a1a568b286612c27ba
Autor:
Si-Bo Zhou, Man Xue, Weiqi Liu, Yu-Xin Chen, Qi-Yu Chen, Jing-Shan Lu, Jinjun Wang, Keqiang Ye, Xu-Hui Li, Min Zhuo
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Long-term potentiation (LTP) is a key cellular mechanism for learning and memory, and recent studies in the hippocampus found that LTP was impaired in aged animals. Previous studies of cortical LTP have focused primarily on the homosynaptic
Externí odkaz:
https://doaj.org/article/d8c4a59128084beea6db2322f4ff0af6
Autor:
Ren-Hao Liu, Mingjie Zhang, Man Xue, Tao Wang, Jing-Shan Lu, Xu-Hui Li, Yu-Xin Chen, Kexin Fan, Wantong Shi, Si-Bo Zhou, Qi-Yu Chen, Li Kang, Qian Song, Shengyuan Yu, Min Zhuo
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106790- (2023)
Summary: Migraines are a common medical condition. From a basic science point of view, the central mechanism for migraine and headache is largely unknown. In the present study, we demonstrate that cortical excitatory transmission is significantly enh
Externí odkaz:
https://doaj.org/article/e6e006e6d4214ca0ada79fc211dfa706
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 15 (2023)
Chronic pain is long-lasting pain that often persists during chronic diseases or after recovery from disease or injury. It often causes serious side effects, such as insomnia, anxiety, or depression which negatively impacts the patient’s overall qu
Externí odkaz:
https://doaj.org/article/0a2309a22f0048cbaacbdedd4607e35f
Autor:
Zhaoxiang Zhou, Penghai Ye, Xu-Hui Li, Yuxiang Zhang, Muhang Li, Qi-Yu Chen, Jing-Shan Lu, Man Xue, Yanan Li, Weiqi Liu, Lin Lu, Wantong Shi, Ping-Yi Xu, Min Zhuo
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Parkinson’s disease (PD) is a multi-system neurodegenerative disorder. Patients with PD often suffer chronic pain. In the present study, we investigated motor, sensory and emotional changes in three different PD mice models. We found that
Externí odkaz:
https://doaj.org/article/8d3f98e132d14b2b9478cacc6a82f1e6