Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Qi-You Yu"'
Autor:
Jyh-Ming Jimmy Juang, Tzu-Pin Lu, Ming-Wei Su, Chien-Wei Lin, Jenn-Hwai Yang, Hou-Wei Chu, Chien-Hsiun Chen, Yi-Wen Hsiao, Chien-Yueh Lee, Li-Mei Chiang, Qi-You Yu, Chuhsing Kate Hsiao, Ching-Yu Julius Chen, Pei-Ei Wu, Chien-Hua Pai, Eric Y. Chuang, Chen-Yang Shen
Publikováno v:
Journal of Advanced Research, Vol 30, Iss , Pp 147-158 (2021)
Introduction: A population-specific genomic reference is important for research and clinical practice, yet it remains unavailable for Han Chinese (HC) in Taiwan. Objectives: We report the first whole genome sequencing (WGS) database of HC (1000 Taiwa
Externí odkaz:
https://doaj.org/article/9022988ea22547ef96ec142bdbfe0cc8
Autor:
Qi-You Yu, Tzu-Pin Lu, Tzu-Hung Hsiao, Ching-Heng Lin, Chi-Yun Wu, Jung-Ying Tzeng, Chuhsing Kate Hsiao
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Genomic studies have been a major approach to elucidating disease etiology and to exploring potential targets for treatments of many complex diseases. Statistical analyses in these studies often face the challenges of multiplicity, weak signals, and
Externí odkaz:
https://doaj.org/article/26dec9d359274d64b573f8c6a9638280
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophages comprise the front line of defense against various pathogens. Classically activated macrophages (M1), induced by IFN-γ and LPS, highly express inflammatory cytokines and contribute to inflammatory processes. By contrast, alternatively ac
Externí odkaz:
https://doaj.org/article/b5491e21c5154253bd553f365c05c89d
Autor:
Amanda Brucker, Wenbin Lu, Rachel Marceau West, Qi-You Yu, Chuhsing Kate Hsiao, Tzu-Hung Hsiao, Ching-Heng Lin, Patrik K E Magnusson, Patrick F Sullivan, Jin P Szatkiewicz, Tzu-Pin Lu, Jung-Ying Tzeng
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007797 (2020)
Copy number variants (CNVs) are the gain or loss of DNA segments in the genome that can vary in dosage and length. CNVs comprise a large proportion of variation in human genomes and impact health conditions. To detect rare CNV associations, kernel-ba
Externí odkaz:
https://doaj.org/article/88a8bc6a56c04085b78960c936494bce
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Current methods for gene-set or pathway analysis are usually designed to test the enrichment of a single gene-set. Once the analysis is carried out for each of the sets under study, a list of significant sets can be obtained. Howe
Externí odkaz:
https://doaj.org/article/48995d5e79854935978e77fac8a6dc8e
107
With the fast progress in sequencing technologies, multiple levels of genomic data can now be obtained from a single set of samples; for instance, SNP array can be efficiently used to genotype SNPs and measure CNVs. The data sizes increase d
With the fast progress in sequencing technologies, multiple levels of genomic data can now be obtained from a single set of samples; for instance, SNP array can be efficiently used to genotype SNPs and measure CNVs. The data sizes increase d
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/953zfz
Autor:
Ming-Wei Su, Jyh-Ming Jimmy Juang, Qi-You Yu, Tzu-Pin Lu, Chien-Yueh Lee, Chuhsing Kate Hsiao, Chien-Hsiun Chen, Eric Y. Chuang, Chen-Yang Shen, Chien-Hua Pai, Li-Mei Chiang, Hou-Wei Chu, Yi-Wen Hsiao, Ching-Yu Julius Chen, Chien-Wei Lin, Pei-Ei Wu, Jenn-Hwai Yang
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 30, Iss, Pp 147-158 (2021)
Journal of Advanced Research, Vol 30, Iss, Pp 147-158 (2021)
Graphical abstract
Introduction A population-specific genomic reference is important for research and clinical practice, yet it remains unavailable for Han Chinese (HC) in Taiwan. Objectives We report the first whole genome sequencing (WGS) data
Introduction A population-specific genomic reference is important for research and clinical practice, yet it remains unavailable for Han Chinese (HC) in Taiwan. Objectives We report the first whole genome sequencing (WGS) data
Autor:
Ching-Yu Julius Chen, Chih-Chien Yu, Shih-Fan Sherri Yeh, Juey-Jen Hwang, Qi-You Yu, Ting-Tse Lin, Min-Tsun Liao, Wen-Jone Chen, Tzu-Pin Lu, Dun-Hui Yang, Amrita Chattopadhyay, Jien-Jiun Chen, Ling Ping Lai, Jiunn-Lee Lin, Eric Y. Chuang, Jing-Yuan Chuang, Jyh-Ming Jimmy Juang, Lian-Yu Lin, Li-Ting Ho, Michael J. Ackerman, Hui-Chun Huang, Yen-Bin Liu
Publikováno v:
Circulation. Genomic and Precision Medicine
Supplemental Digital Content is available in the text.
Background: Brugada syndrome (BrS) is an oligogenic arrhythmic disease with increased risk of sudden cardiac arrest. Several BrS or ECG traits-related single-nucleotide polymorphisms (SNPs)
Background: Brugada syndrome (BrS) is an oligogenic arrhythmic disease with increased risk of sudden cardiac arrest. Several BrS or ECG traits-related single-nucleotide polymorphisms (SNPs)
Autor:
Chuhsing Kate Hsiao, Jung-Ying Tzeng, Patrick Sullivan, Jin P. Szatkiewicz, Amanda Brucker, Wenbin Lu, Tzu-Pin Lu, Qi You Yu, Patrik K. E. Magnusson, Ching-Heng Lin, Rachel Marceau West, Tzu Hung Hsiao
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007797 (2020)
PLoS Computational Biology
PLoS Computational Biology
Copy number variants (CNVs) are the gain or loss of DNA segments in the genome that can vary in dosage and length. CNVs comprise a large proportion of variation in human genomes and impact health conditions. To detect rare CNV associations, kernel-ba
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-10 (2018)
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-10 (2018)
Background Current methods for gene-set or pathway analysis are usually designed to test the enrichment of a single gene-set. Once the analysis is carried out for each of the sets under study, a list of significant sets can be obtained. However, if o