Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Qi-Xin Wen"'
Autor:
Jian Chen, Biao Luo, Bi-Rou Zhong, Kun-Yi Li, Qi-Xin Wen, Li Song, Xiao-Jiao Xiang, Gui-Feng Zhou, Li-Tian Hu, Xiao-Juan Deng, Yuan-Lin Ma, Guo-Jun Chen
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 867-881 (2021)
Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and inflammation. In this study, we investigated the role of sulfuretin in the processing of amyloid precursor protein (APP), in association with the two cata
Externí odkaz:
https://doaj.org/article/67b39b39ae2a43ac81a57e12a858650c
Autor:
Biao Luo, Jian Chen, Gui‐Feng Zhou, Xiao‐Yong Xie, Jing Tang, Qi‐Xin Wen, Li Song, Shi‐Qi Xie, Yan Long, Guo‐Jun Chen, Xiao‐Tong Hu
Publikováno v:
CNS Neuroscience & Therapeutics. 29:1300-1311
Autor:
Li-Tian Hu, Xiao-Yong Xie, Gui-Feng Zhou, Qi-Xin Wen, Li Song, Biao Luo, Xiao-Juan Deng, Qiu-Ling Pan, Guo-Jun Chen
Publikováno v:
Journal of Alzheimer's disease : JAD. 91(1)
Background: Accumulation of hyperphosphorylated Tau (pTau) contributes to the formation of neurofibrillary tangles in Alzheimer’s disease (AD), and targeting Tau/pTau metabolism has emerged as a therapeutic approach. We have previously reported tha
Autor:
Qi‐Xin Wen, Biao Luo, Xiao‐Yong Xie, Gui‐Feng Zhou, Jian Chen, Li Song, Yue Liu, Shi‐Qi Xie, Long Chen, Kun‐Yi Li, Xiao‐Jiao Xiang, Guo‐Jun Chen
Publikováno v:
Traffic (Copenhagen, Denmark)REFERENCES.
AP2S1 is the sigma 2 subunit of adaptor protein 2 (AP2) that is essential for endocytosis. In this study, we investigated the potential role of AP2S1 in intracellular processing of amyloid precursor protein (APP), which contributes to the pathogenesi
Autor:
Long Chen, Lu Wang, Gui-Feng Zhou, Yue Liu, Xue Chen, Xiao-Yong Xie, Qi-Xin Wen, Chen-Lu Li, Jie Yang, Guo-Jun Chen
Publikováno v:
Neuroscience Letters. 808:137265
Akademický článek
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Autor:
Bi-Rou Zhong, Guojun Chen, Li Song, Biao Luo, Yuanlin Ma, Li-Tian Hu, Gui-Feng Zhou, Qi-Xin Wen, Xiao-Juan Deng, Kun-Yi Li, Xiao-Jiao Xiang, Jian Chen
Publikováno v:
Journal of Neurochemistry. 157:1351-1365
Thioredoxin-2 (TXN2) is a mitochondrial protein and represents one of the intrinsic antioxidant enzymes. It has long been recognized that mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of Alzheimer's disease (AD). We hy
Autor:
Li Song, Bi-Rou Zhong, Guojun Chen, Xiao-Juan Deng, Gui-Feng Zhou, Li-Tian Hu, Yuanlin Ma, Qi-Xin Wen
Publikováno v:
The FASEB Journal. 35
Mitochondrial Tu translation elongation factor (TUFM or EF-Tu) is part of the mitochondrial translation machinery. It is reported that TUFM expression is reduced in the brain of Alzheimer's disease (AD), suggesting that TUFM might play a role in the
Autor:
Bing-Lin Zhu, Zhen Yan, Xiao-Juan Deng, Kun-Yi Li, Zhuo Min, Guojun Chen, Jian Chen, Xiao-Jiao Xiang, Ying Tang, Biao Luo, Yuanlin Ma, Li Song, Qi-Xin Wen
Publikováno v:
Experimental neurology. 318
Methionine sulfoxide reductase B2 (MSRB2) is a mitochondrial protein that protects cell from oxidative stress. The antioxidant activity suggests that MSRB2 may play a role in the pathophysiology of Alzheimer's disease (AD). Here, we report that in AP