Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Qi-Lei Zhang"'
Autor:
Chen Yang, Zhong-Ping Sun, Juan Jiang, Xiao-Lu Cai, Yan Wang, Hui Wang, Chong Che, Ewen Tu, Ai-hua Pan, Yan Zhang, Xiao-Ping Wang, Mei-Zhen Cui, Xue-min Xu, Xiao-Xin Yan, Qi-Lei Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Presenilin-associated protein (PSAP) is a mitochondrial proapoptotic protein as established in cell biology studies. It remains unknown whether it involves in neurodegenerative diseases. Here, we explored PASP expression in adult and aged hu
Externí odkaz:
https://doaj.org/article/fe7c5aa21bb943f0a251463613b429aa
Autor:
Juan Jiang, Chen Yang, Jia-Qi Ai, Qi-Lei Zhang, Xiao-Lu Cai, Tian Tu, Lily Wan, Xiao-Sheng Wang, Hui Wang, Aihua Pan, Jim Manavis, Wei-Ping Gai, Chong Che, Ewen Tu, Xiao-Ping Wang, Zhen-Yan Li, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Extracellular β-amyloid (Aβ) deposition and intraneuronal phosphorylated-tau (pTau) accumulation are the hallmark lesions of Alzheimer’s disease (AD). Recently, “sorfra” plaques, named for the extracellular deposition of sortilin c-terminal f
Externí odkaz:
https://doaj.org/article/5b526986a2b54f6b9f2e43d6bf886cd3
Autor:
Lily Wan, Jia-Qi Ai, Chen Yang, Juan Jiang, Qi-Lei Zhang, Zhao-Hui Luo, Rou-Jie Huang, Tian Tu, Aihua Pan, Ewen Tu, Jim Manavis, Bo Xiao, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Shank3 is a postsynaptic scaffolding protein of excitatory synapses. Mutations or variations of SHANK3 are associated with various psychiatric and neurological disorders. We set to determine its normal expression pattern in the human brain, and its c
Externí odkaz:
https://doaj.org/article/dd43ca1e535641c2a7239293cca61506
Autor:
Jin Zheng, Tai-Jie Zhang, Bo-Hui Li, Wei-Jie Liang, Qi-Lei Zhang, Min-Ling Cai, Chang-Lian Peng
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Phenotypic plasticity affords invasive plant species the ability to colonize a wide range of habitats, but physiological plasticity of their stems is seldom recognized. Investigation of the stem plasticity of invasive plant species could lead to a be
Externí odkaz:
https://doaj.org/article/a18263474af34a89923ef0922b060114
Autor:
Yan-Bin Shi, Tian Tu, Juan Jiang, Qi-Lei Zhang, Jia-Qi Ai, Aihua Pan, Jim Manavis, Ewen Tu, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Dystrophic neurites (DNs) are found in many neurological conditions such as traumatic brain injury and age-related neurodegenerative diseases. In Alzheimer’s disease (AD) specifically, senile plaques containing silver-stained DNs were already descr
Externí odkaz:
https://doaj.org/article/d06eb15a71a646c89187a811dd37da50
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Amyloid plaques and neurofibrillary tangles (NFTs) are hallmark lesions of Alzheimer’s disease (AD) related to β-amyloid (Aβ) deposition and intraneuronal phosphorylated tau (pTau) accumulation. Sortilin C-terminal fragments (shortened as “sorf
Externí odkaz:
https://doaj.org/article/6feff2f6875b4cf187b8e4d92cb83bd8
Autor:
Shu-Yin Xu, Qi-Lei Zhang, Qi Zhang, Lily Wan, Juan Jiang, Tian Tu, Jim Manavis, Aihua Pan, Yan Cai, Xiao-Xin Yan
Publikováno v:
Frontiers in Neuroanatomy, Vol 13 (2019)
Sortilin is a member of the vacuolar protein sorting 10 protein (VPS10P) domain receptor family, which carries out signal transduction and protein transport in cells. Sortilin serves as the third, G-protein uncoupled, receptor of neurotensin that can
Externí odkaz:
https://doaj.org/article/93fc8cd83b594325a4d86085ac4ac4ac
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Adult neurogenesis in the hippocampal dentate gyrus (DG) modulates cognition and behavior in mammals, while motherhood is associated with cognitive and behavioral changes essential for the care of the young. In mice and rats, hippocampal neurogenesis
Externí odkaz:
https://doaj.org/article/b7dedcf596984f84998ed2bdc5598b84
Autor:
Ya-Nan Li, Dan-Dan Hu, Xiao-Lu Cai, Yan Wang, Chen Yang, Juan Jiang, Qi-Lei Zhang, Tian Tu, Xiao-Sheng Wang, Hui Wang, Ewen Tu, Xiao-Ping Wang, Aihua Pan, Xiao-Xin Yan, Lily Wan
A cohort of morphologically heterogenous doublecortin immunoreactive (DCX+) “immature neurons” has been identified in the cerebral cortex largely around layer II and the amygdala largely in the paralaminar nucleus (PLN) among various mammals. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94d5cbfd4d5b306e4e834b10f218817
https://doi.org/10.21203/rs.3.rs-2168886/v1
https://doi.org/10.21203/rs.3.rs-2168886/v1
Autor:
Huan-Yu Che, Jia-Qi Ai, Chen Yang, Xiao-Lu Cai, Yan Wang, Juan Jiang, Qi-Lei Zhang, Tian Tu, Ewen Tu, Chong Che, Xiao-Xin Yan
Publikováno v:
Human Brain. 1
β-Amyloid (Aβ) deposition is a commonly studied neuropathology in the human brain, occurring as compact and diffuse parenchymal plaques, cerebral amyloid angiopathy (CAA), and meningeal/subpial amyloidosis. Compact plaques associated with dystrophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d143af02f55dec80a314643f61b9da6
https://doi.org/10.37819/hb.001.001.0206
https://doi.org/10.37819/hb.001.001.0206