Effects of Glucosinolate-Rich Broccoli Sprouts on Urinary Levels of Aflatoxin-DNA Adducts and Phenanthrene Tetraols in a Randomized Clinical Trial in He Zuo Township, Qidong, People's Republic of China

Autor: Jin Bing Wang, Jamie L. Coady, Katherine K. Stephenson, Bao Chu Zhang, Yan Sun, Paul Talalay, Patricia A. Egner, Jianguo Chen, Stephen S. Hecht, Stephen J. Gange, Lingxiang Ye, Yan Wu, Thomas W. Kensler, Qi Nan Zhang, Geng Sun Qian, Lisa P. Jacobson, John D. Groopman, Lorie Benning, Jed W. Fahey, Yuan Rong Zhu, Stephen G. Carmella

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 14:2605-2613

Residents of Qidong, People's Republic of China, are at high risk for development of hepatocellular carcinoma, in part due to consumption of aflatoxin-contaminated foods, and are exposed to high levels of phenanthrene, a sentinel of hydrocarbon air t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f65d71286ad6bad1ae3780e0c3a5e6f
https://doi.org/10.1158/1055-9965.epi-05-0368

Oltipraz chemoprevention trial in Qidong, Jiangsu Province, People's Republic of China

Autor: Thomas W. Kensler, Hans J. Prochaska, Shuang Yuan Kuang, Baibai Chen, Jia-Sheng Wang, Geng Sun Qian, Mary B. Gorman, John D. Groopman, Xia He, Yuan Rong Zhu, Bao Chu Zhang, Audrey Zarba, Lu Yi Yu, Kathy J. Helzlsouer, Patricia A. Egner, Yan Wu, Xi Fang, Alvaro Muñoz, Yan Feng Li, Cheryl Enger, Lisa P. Jacobson, Gary B. Gordon, Jin Bing Wang, Silvio De Flora, Qi Nan Zhang, Nancy E. Davidson

Publikováno v: Journal of Cellular Biochemistry. 67:166-173

Oltipraz has been used clinically in many regions of the world as an antischistosomal agent and is an effective inhibitor of aflatoxin hepatocarcinogenesis in rats. This chemopreventive action of oltipraz results primarily from an altered balance in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::712c4f591bc46fda7a7428e31c1058f5
https://doi.org/10.1002/(sici)1097-4644(1997)28/29+<166::aid-jcb20>3.0.co

[Longitudinal study of aflatoxin exposure in the development of primary liver cancer in patients with chronic hepatitis]

Autor: Pei-xin, Lu, Jin-bing, Wang, Qi-nan, Zhang, Yan, Wu, Yan, Sun, Tao-yang, Chen

Publikováno v: Zhonghua yi xue za zhi. 90(24)

To study the relationship between aflatoxin exposure and the development of primary liver cancer (PLC) in patients with chronic hepatitis.A 21-year longitudinal study was carried out in a large cohort of 515 PLC high-risk individuals with HBV infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ffe44608b9f4de40b743ce42a32655a
https://pubmed.ncbi.nlm.nih.gov/20979873

Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver...

Autor: Egner, Patricia A., Jin-Bing Wang, Yuan-Rhong Zhu, Bao-Chu Zhang, Yan Wu, Qi-Nan Zhang, Geng-Sun Qian, Shuang-Yuan Kuang, Gange, Stephen J., Jacobson, Lisa P., Helzlsouer, Kathy J., Bailey, George S., Groopman, John D., Kensler, Thomas W.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 12/4/2001, Vol. 98 Issue 25, p14601, 6p, 2 Diagrams, 1 Chart, 6 Graphs