Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Qi‐Nian Wu"'
Autor:
Jia-Jun Li, Jin-Hong Wang, Tian Tian, Jia Liu, Yong-Qiang Zheng, Hai-Yu Mo, Hui Sheng, Yan-Xing Chen, Qi-Nian Wu, Yi Han, Kun Liao, Yi-Qian Pan, Zhao-Lei Zeng, Ze-Xian Liu, Wei Yang, Rui-Hua Xu, Huai-Qiang Ju
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Colorectal cancer (CRC) patients with liver metastases usually obtain less benefit from immunotherapy, and the underlying mechanisms remain understudied. Here, we identify that fibrinogen-like protein 1 (FGL1), secreted from cancer cells and
Externí odkaz:
https://doaj.org/article/a415806161184e21aefb5011dd83861d
Autor:
Jia Liu, Wei‐Yi Zhou, Xiao‐Jing Luo, Yan‐Xing Chen, Chau‐Wei Wong, Ze‐Xian Liu, Jia‐ Bo Zheng, Hai‐ Yu Mo, Jun‐Quan Chen, Jia‐Jun Li, Ming Zhong, Yu‐Hong Xu, Qi‐Hua Zhang, Heng‐Ying Pu, Qi‐Nian Wu, Ying Jin, Zi‐Xian Wang, Rui‐Hua Xu, Hui‐Yan Luo
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 9, Pp n/a-n/a (2023)
Abstract Background Predictive biomarkers for oesophageal squamous cell carcinoma (ESCC) immunotherapy are lacking, and immunotherapy resistance remains to be addressed. The role of long noncoding RNA (lncRNA) in ESCC immune escape and immunotherapy
Externí odkaz:
https://doaj.org/article/e857b4e2202441d4be456278ca075e04
Autor:
Miao-Zhen Qiu, Qingjian Chen, Dan-Yang Zheng, Qi Zhao, Qi-Nian Wu, Zhi-Wei Zhou, Li-Qiong Yang, Qiu-Yun Luo, Yu-Ting Sun, Ming-Yu Lai, Sha-Sha Yuan, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Yu-Hong Li, Hui-Zhong Zhang, Rui-Hua Xu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112576- (2023)
Summary: Gastric mixed adenoneuroendocrine carcinoma (MANEC) is a clinically aggressive and heterogeneous tumor composed of adenocarcinoma (ACA) and neuroendocrine carcinoma (NEC). The genomic properties and evolutionary clonal origins of MANEC remai
Externí odkaz:
https://doaj.org/article/bf5aeca0e50d4f5bb3972a430c761164
Autor:
Qi Zhao, Feng Wang, Yan-Xing Chen, Shifu Chen, Yi-Chen Yao, Zhao-Lei Zeng, Teng-Jia Jiang, Ying-Nan Wang, Chen-Yi Wu, Ying Jing, You-Sheng Huang, Jing Zhang, Zi-Xian Wang, Ming-Ming He, Heng-Ying Pu, Zong-Jiong Mai, Qi-Nian Wu, Renwen Long, Xiaoni Zhang, Tanxiao Huang, Mingyan Xu, Miao-Zheng Qiu, Hui-Yan Luo, Yu-Hong Li, Dong-Shen Zhang, Wei-Hua Jia, Gong Chen, Pei-Rong Ding, Li-Ren Li, Zheng-Hai Lu, Zhi-Zhong Pan, Rui-Hua Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The ChangKang (Heathy Bowel) project was established to collect molecular and clinical information of a thousand Chinese colorectal cancer patients. Here, the authors present the genomic landscape of the ChangKang cohort and find a subgroup of patien
Externí odkaz:
https://doaj.org/article/ee0548bf4a574cba8d5b0964a7e38b91
Autor:
Jin-Fei Lin, Pei-Shan Hu, Yi-Yu Wang, Yue-Tao Tan, Kai Yu, Kun Liao, Qi-Nian Wu, Ting Li, Qi Meng, Jun-Zhong Lin, Ze-Xian Liu, Heng-Ying Pu, Huai-Qiang Ju, Rui-Hua Xu, Miao-Zhen Qiu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Metabolic enzymes have an indispensable role in metabolic reprogramming, and their aberrant expression or activity has been associated with chemosensitivity. Hence, targeting metabolic enzymes remains an attractive approach for treating tumo
Externí odkaz:
https://doaj.org/article/7483466092b04591b6d913a49def38e6
Autor:
Zhao‐lei Zeng, Jia‐huan Lu, Yun Wang, Hui Sheng, Ying‐nan Wang, Zhan‐hong Chen, Qi‐nian Wu, Jia‐Bo Zheng, Yan‐xing Chen, Dong‐dong Yang, Kai Yu, Hai‐yu Mo, Jia‐jia Hu, Pei‐shan Hu, Ze‐xian Liu, Huai‐qiang Ju, Rui‐Hua Xu
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2423-2441 (2021)
Abstract Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorect
Externí odkaz:
https://doaj.org/article/39ec1ebf35c944a5aefe92e4611f5aa4
Autor:
Jia Liu, Ze-Xian Liu, Qi-Nian Wu, Yun-Xin Lu, Chau-Wei Wong, Lei Miao, Yun Wang, Zixian Wang, Ying Jin, Ming-Ming He, Chao Ren, De-Shen Wang, Dong-Liang Chen, Heng-Ying Pu, Lin Feng, Bo Li, Dan Xie, Mu-Sheng Zeng, Peng Huang, Aifu Lin, Dongxin Lin, Rui-Hua Xu, Huai-Qiang Ju
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
PFKFB3 enhances glycolysis to promote cancer cell proliferation. Here, the authors identify a long noncoding RNA in esophageal squamous cell carcinoma, AGPG, which interacts with PFKFB3 and promotes its stability, leading to increased glycolysis and
Externí odkaz:
https://doaj.org/article/991c7443503b477c92252788160db378
Autor:
Yun Wang, Jia-Huan Lu, Qi-Nian Wu, Ying Jin, De-Shen Wang, Yan-Xing Chen, Jia Liu, Xiao-Jing Luo, Qi Meng, Heng-Ying Pu, Ying-Nan Wang, Pei-Shan Hu, Ze-Xian Liu, Zhao-Lei Zeng, Qi Zhao, Rong Deng, Xiao-Feng Zhu, Huai-Qiang Ju, Rui-Hua Xu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-18 (2019)
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that promotes the colorectal cancer (CRC) progression and could be a potential the
Externí odkaz:
https://doaj.org/article/cd254d1cc795495d9725359a49bd532b
Autor:
Huai‐Qiang Ju, Qi Zhao, Feng Wang, Ping Lan, Zixian Wang, Zhi‐Xiang Zuo, Qi‐Nian Wu, Xin‐Juan Fan, Hai‐Yu Mo, Li Chen, Ting Li, Chao Ren, Xiang‐Bo Wan, Gong Chen, Yu‐Hong Li, Wei‐Hua Jia, Rui‐Hua Xu
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 10, Pp 1-13 (2019)
Abstract Accurate risk stratification for patients with stage II/III colon cancer is pivotal for postoperative treatment decisions. Here, we aimed to identify and validate a circRNA‐based signature that could improve postoperative prognostic strati
Externí odkaz:
https://doaj.org/article/94e8fd3a10b94556b180eefd64ab1aa9
Autor:
Ting Li, Pei-Shan Hu, Zhixiang Zuo, Jin-Fei Lin, Xingyang Li, Qi-Nian Wu, Zhan-Hong Chen, Zhao-Lei Zeng, Feng Wang, Jian Zheng, Demeng Chen, Bo Li, Tie-Bang Kang, Dan Xie, Dongxin Lin, Huai-Qiang Ju, Rui-Hua Xu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract Background Colorectal carcinoma (CRC) is one of the most common malignant tumors, and its main cause of death is tumor metastasis. RNA N6-methyladenosine (m6A) is an emerging regulatory mechanism for gene expression and methyltransferase-lik
Externí odkaz:
https://doaj.org/article/76624111e6ca4679bf92d36b6906d172