Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Qais Al-Awqati"'
Autor:
Pamela I. Good, Ling Li, Holly A. Hurst, Ileana Serrano Herrera, Katherine Xu, Meenakshi Rao, David A. Bateman, Qais Al-Awqati, Vivette D. D’Agati, Frank Costantini, Fangming Lin
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
Preterm birth results in low nephron endowment and increased risk of acute kidney injury (AKI) and chronic kidney disease (CKD). To understand the pathogenesis of AKI and CKD in preterm humans, we generated potentially novel mouse models with a 30%
Externí odkaz:
https://doaj.org/article/c77b63374e4a4df497ef65ec62d8c85d
Autor:
Juan A. Oliver, Rosemary V. Sampogna, Sumreen Jalal, Qing-Yin Zhang, Alexander Dahan, Weiwei Wang, Tian Huai Shen, Qais Al-Awqati
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 757-771 (2016)
To determine whether adult kidney papillary label-retaining cells (pLRCs) are specialized precursors, we analyzed their transcription profile. Among genes overexpressed in pLRCs, we selected candidate genes to perform qPCR and immunodetection of thei
Externí odkaz:
https://doaj.org/article/d24146ef19bb43e9bfc701279801ddb6
Autor:
Max Werth, Kai M Schmidt-Ott, Thomas Leete, Andong Qiu, Christian Hinze, Melanie Viltard, Neal Paragas, Carrie J Shawber, Wenqiang Yu, Peter Lee, Xia Chen, Abby Sarkar, Weiyi Mu, Alexander Rittenberg, Chyuan-Sheng Lin, Jan Kitajewski, Qais Al-Awqati, Jonathan Barasch
Publikováno v:
eLife, Vol 6 (2017)
Although most nephron segments contain one type of epithelial cell, the collecting ducts consists of at least two: intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively. In adult kidneys, these
Externí odkaz:
https://doaj.org/article/24d5342b565a4432ae63499df84881e5
Autor:
Pietro A. Canetta, Irina Y. Baramidze, Krzysztof Kiryluk, Sean Kalloo, Syeda B. Ahmad, Bessie N. Craig, Maya K. Rao, Jason Zheng, Jonathan Barasch, Jane Akomeah, Syed A. Husain, Vaqar H. Shah, Gail Williams, Jordann Lewis, Robin Ferrer, Maria M. Morban, Shayan Shirazian, Andrew S. Bomback, Andrew A. Moses, Meeran Lee, Jacob S. Stevens, Piotr Starakiewicz, Andrew Beenken, Bradley Nelson, Qais Al-Awqati, Allyson R. Medina, Maddalena Marasa, Vanna M. Nicasio, Stacy Piva, Emily Daniel, Iman Azam Ghavami, Karla Mehl, Geoffrey K. Dube, Simone Sanna-Cherchi, Rosemary V. Sampogna, Bruno Lovisi, Hilda Fernandez, Anthony M. Valeri, Maria Alejandra Aponte, David J. Cohen, Jung Soo Kim, Katherine Toma, Kathryn Paget, Hector Alvarado Verduzco, Sumit Mohan, Jai Radhakrishnan, Eric Siddall, Pascale Khairallah, Jordan G. Nestor, Nisha Clement, Denzil Douglas, Heather Morris, Gerald B. Appel, Ali G. Gharavi, Yonatan Peleg, Donald W. Landry, Wooin Ahn, Daisy Mathew, Russell J. Crew, Jae Hyung Chang, Tom Nickolas
Publikováno v:
J Am Soc Nephrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d72e3af4df63a35bb30fc35206cc11
https://doi.org/10.1681/asn.2020040520
https://doi.org/10.1681/asn.2020040520
Autor:
Qais Al-Awqati, Andrew Beenken
Publikováno v:
Kidney International. 99:1057-1059
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755f722ff3f6b219b5b65ab3c4011eb1
https://doi.org/10.1016/j.kint.2020.12.035
https://doi.org/10.1016/j.kint.2020.12.035
Autor:
Jacob S. Stevens, Qais Al-Awqati
Publikováno v:
J Clin Invest
Increased urinary oxalate excretion (hyperoxaluria) promotes the formation of calcium oxalate crystals. Monogenic diseases due to hepatic enzyme deficiency result in chronic hyperoxaluria, promoting end-stage renal disease in children and young adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067c0381ca046b34cc5a888ad5936031
https://europepmc.org/articles/PMC6546444/
https://europepmc.org/articles/PMC6546444/
Publikováno v:
J Clin Invest
Acute kidney injury (AKI) can lead to chronic kidney disease (CKD) if injury is severe and/or repair is incomplete. However, the pathogenesis of CKD following renal ischemic injury is not fully understood. Capillary rarefaction and tubular hypoxia ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d457688905685288d93e3571c92cb003
https://pubmed.ncbi.nlm.nih.gov/31063992
https://pubmed.ncbi.nlm.nih.gov/31063992
Autor:
Tian Huai Shen, Juan A. Oliver, Alexander Dahan, Qais Al-Awqati, Sumreen Jalal, Qing-Yin Zhang, Rosemary V. Sampogna, Weiwei Wang
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 5, Pp 757-771 (2016)
Stem Cell Reports, Vol 6, Iss 5, Pp 757-771 (2016)
Summary To determine whether adult kidney papillary label-retaining cells (pLRCs) are specialized precursors, we analyzed their transcription profile. Among genes overexpressed in pLRCs, we selected candidate genes to perform qPCR and immunodetection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6b8688b386ceec70144131f851a2f6
https://doi.org/10.1016/j.stemcr.2016.03.008
https://doi.org/10.1016/j.stemcr.2016.03.008
Autor:
Jeffrey M. Purkerson, George J. Schwartz, Vivette D. D'Agati, Dominique Eladari, Xiaobo Gao, Nicolas Picard, Qais Al-Awqati, Shuichi Tsuruoka, Hu Peng
Publikováno v:
Journal of Clinical Investigation. 125:4365-4374
The nephron cortical collecting duct (CCD) is composed of principal cells, which mediate Na, K, and water transport, and intercalated cells (ICs), which are specialized for acid-base transport. There are two canonical IC forms: acid-secreting α-ICs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2180380fa19468898fec985de1dc6899
https://doi.org/10.1172/jci80225
https://doi.org/10.1172/jci80225
Autor:
Qais Al-Awqati
Publikováno v:
Journal of Clinical Investigation. 125:2267-2270
The kidney, like other organs, grows in constant proportion to the rest of the body. When one kidney is removed, the remaining one hypertrophies. In a comprehensive series of studies, Chen et al. show that growth during maturation is mediated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff8fba15d3e443432537298e44fd14d
https://doi.org/10.1172/jci81508
https://doi.org/10.1172/jci81508