Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Qadeer, Aziz"'
Autor:
Cristiana Bercea, Roshan Limbu, Kamila Behnam, Keat-Eng Ng, Qadeer Aziz, Andrew Tinker, Francesco Tamagnini, Graeme S Cottrell, Alister J McNeish
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
There is strong evidence that the omega-3 polyunsaturated fatty acids (n-3 PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have cardioprotective effects. n-3 PUFAs cause vasodilation in hypertensive patients, in part controlled by i
Externí odkaz:
https://doaj.org/article/06d60e08f26d4cb7ae4435d5ae25bc41
Publikováno v:
Bio-Protocol, Vol 10, Iss 1 (2020)
The cardiac conduction system allows the synchronized propagation of electrical activity through heart muscle. This is initiated by the spontaneous activity of the specialized pacemaker cells of the sino-atrial node (SAN). The SAN region underlies au
Externí odkaz:
https://doaj.org/article/031c07dae2ec4107a35dfabd06f0e45d
Whole-cell and Perforated Patch-clamp Recordings from Acutely-isolated Murine Sino-atrial Node Cells
Publikováno v:
Bio-Protocol, Vol 10, Iss 1 (2020)
Cardiac pacemaker cells of the sino-atrial node are responsible for the initiation of the heart beat and express an array of ion channels. The patch-clamp technique is the gold standard method for investigating the function of ion channels expressed
Externí odkaz:
https://doaj.org/article/ca95b30fd9d948ff86c777549a6a7bd5
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
In the endothelium, ATP-sensitive potassium (KATP) channels are thought to couple cellular metabolism with membrane excitability, calcium entry, and endothelial mediator release. We hypothes
In the endothelium, ATP-sensitive potassium (KATP) channels are thought to couple cellular metabolism with membrane excitability, calcium entry, and endothelial mediator release. We hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c3b97601429132850a7714d6579c1c
http://europepmc.org/articles/PMC7418932
http://europepmc.org/articles/PMC7418932
Autor:
Andrew Tinker, Amie J Moyes, Qadeer Aziz, Sonia Sebastian, Christoph Thiemermann, Jianmin Chen, Richard Ang, Naomi Anderson, Dunja Aksentijevic, Adrian J. Hobbs, Yiwen Li
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
KATPchannels in the vasculature composed of Kir6.1 regulate vascular tone and may contribute to the pathogenesis of endotoxemia. We used mice with cell-specific deletion of Kir6.1 in smooth muscle (smKO) and endothelium (eKO) to investigate this ques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b344f12b04b473473c9917d4f67c22
http://europepmc.org/articles/PMC7399691
http://europepmc.org/articles/PMC7399691
Autor:
Antonia Solomou, Anisha Mistry, Andrew Tinker, Marta Korbonits, Maria Lillina Vignola, Francisca Caimari, Maria Herincs, Qadeer Aziz, Carles Gaston-Massuet, Lim Chung Thong, Sonia Sebastian, Gregory Funge
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b557603ebdab130bad85538b7cdec3de
https://doi.org/10.1530/endoabs.77.oc1.3
https://doi.org/10.1530/endoabs.77.oc1.3
Publikováno v:
Handbook of experimental pharmacology. 267
ATP-sensitive K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ac9b6e42648dbbde4b6e2a1d888dc82
https://pubmed.ncbi.nlm.nih.gov/34247283
https://pubmed.ncbi.nlm.nih.gov/34247283
Autor:
Patricia B. Munroe, Qadeer Aziz, Andrew Tinker, Sudhin Thayyil, Stephen C Harmer, James H. Cartwright
Publikováno v:
Cartwright, J H, Aziz, Q, Harmer, S C, Thayyil, S, Tinker, A & Munroe, P B 2019, ' Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddz198
Human Molecular Genetics
Human Molecular Genetics
Stillbirth is the loss of a fetus after 22 weeks of gestation, of which almost half go completely unexplained despite post-mortem. We recently sequenced 35 arrhythmia-associated genes from 70 unexplained stillbirth cases. Our hypothesis was that dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8bc638e7dc05c004c45efbfc73d5f7
https://doi.org/10.1093/hmg/ddz198
https://doi.org/10.1093/hmg/ddz198
Publikováno v:
EP Europace. 23
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): British Heart Foundation Phosphatidylinositol-4,5-biphosphate (PIP2) is implicated in the regulation and modulation of the IKS channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce28b6df22a5db4e9b6567009dac239e
https://doi.org/10.1093/europace/euab116.543
https://doi.org/10.1093/europace/euab116.543
Publikováno v:
Pharmacology of Potassium Channels ISBN: 9783030840518
ATP-sensitive K+ channels (KATP) are inwardly-rectifying potassium channels, broadly expressed throughout the body. KATP is regulated by adenine nucleotides, characteristically being activated by falling ATP and rising ADP levels thus playing an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89cc50e912d46afe3add8873f5bcc08
https://doi.org/10.1007/164_2021_466
https://doi.org/10.1007/164_2021_466
