Zobrazeno 1 - 10
of 261
pro vyhledávání: '"QUNXIN SHE"'
Autor:
Xu Feng, Ruyi Xu, Jianglan Liao, Jingyu Zhao, Baochang Zhang, Xiaoxiao Xu, Pengpeng Zhao, Xiaoning Wang, Jianyun Yao, Pengxia Wang, Xiaoxue Wang, Wenyuan Han, Qunxin She
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract TnpBs encoded by the IS200/IS605 family transposon are among the most abundant prokaryotic proteins from which type V CRISPR-Cas nucleases may have evolved. Since bacterial TnpBs can be programmed for RNA-guided dsDNA cleavage in the presenc
Externí odkaz:
https://doaj.org/article/4f6c2584a778471f9fdf4df72a7dc107
Publikováno v:
mLife, Vol 3, Iss 1, Pp 119-128 (2024)
Abstract Saccharolobus islandicus REY15A represents one of the very few archaeal models with versatile genetic tools, which include efficient genome editing, gene silencing, and robust protein expression systems. However, plasmid vectors constructed
Externí odkaz:
https://doaj.org/article/15d3d903b0a74ec8aad69b5c0d06527c
Autor:
Fabian Blombach, Michal Sýkora, Jo Case, Xu Feng, Diana P. Baquero, Thomas Fouqueau, Duy Khanh Phung, Declan Barker, Mart Krupovic, Qunxin She, Finn Werner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract CRISPR arrays form the physical memory of CRISPR adaptive immune systems by incorporating foreign DNA as spacers that are often AT-rich and derived from viruses. As promoter elements such as the TATA-box are AT-rich, CRISPR arrays are prone
Externí odkaz:
https://doaj.org/article/ae9128ebd98f4588bdf6f50de591a387
Autor:
Xinmi Song, Sheng Lei, Shunhang Liu, Yanqiu Liu, Pan Fu, Zhifeng Zeng, Ke Yang, Yu Chen, Ming Li, Qunxin She, Wenyuan Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Argonaute proteins (Agos) bind short nucleic acids as guides and are directed by them to recognize target complementary nucleic acids. Diverse prokaryotic Agos (pAgos) play potential functions in microbial defense. The functions and mechanis
Externí odkaz:
https://doaj.org/article/29637690cecc4ce3a91fb391be7745ac
Autor:
Yuanxi Xiao, Zhichao Jiang, Mengqi Zhang, Xuemei Zhang, Qi Gan, Yunfeng Yang, Pengju Wu, Xu Feng, Jinfeng Ni, Xiuzhu Dong, Qunxin She, Qihong Huang, Yulong Shen
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108389- (2023)
Summary: Single-stranded DNA-binding proteins (SSBs) have been regarded as indispensable replication factors. Herein, we report that the genes encoding the canonical SSB (SisSSB) and the non-canonical SSB (SisDBP) in Saccharolobus islandicus REY15A a
Externí odkaz:
https://doaj.org/article/bb12f4bacd36494a957bc870ed4121a2
Publikováno v:
Engineering Microbiology, Vol 3, Iss 4, Pp 100102- (2023)
Type III CRISPR-Cas10 systems employ multiple immune activities to defend their hosts against invasion from mobile genetic elements (MGEs), including DNase and cyclic oligoadenylates (cOA) synthesis both of which are hosted by the type-specific prote
Externí odkaz:
https://doaj.org/article/fa3b4076651042d4b7e6e0b99d691c12
Autor:
Pengju Wu, Qi Gan, Xuemei Zhang, Yunfeng Yang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Qihong Huang, Yulong Shen
Publikováno v:
mLife, Vol 2, Iss 1, Pp 11-27 (2023)
Abstract Kinase, putative Endopeptidase, and Other Proteins of Small size (KEOPS) is a multisubunit protein complex conserved in eukaryotes and archaea. It is composed of Pcc1, Kae1, Bud32, Cgi121, and Gon7 in eukaryotes and is primarily involved in
Externí odkaz:
https://doaj.org/article/03dd62564fdd4551adb54f2b63ba7467
Autor:
Zhichao Jiang, Zijia Lin, Qi Gan, Pengju Wu, Xuemei Zhang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Yulong Shen, Qihong Huang
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Forkhead-associated (FHA) domain proteins specifically recognize phosphorylated threonine via the FHA domain and are involved in signal transduction in various processes especially DNA damage response (DDR) and cell cycle regulation in eukar
Externí odkaz:
https://doaj.org/article/875cfec00b9543ddad0877abc5cc76ca
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
Externí odkaz:
https://doaj.org/article/33b3deeb112544fba731ac69b143cc27
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2857 (2023)
In cancer diagnosis, diverse microRNAs (miRNAs) are used as biomarkers for carcinogenesis of distinctive human cancers. Thus, the detection of these miRNAs and their quantification are very important in prevention of cancer diseases in human beings.
Externí odkaz:
https://doaj.org/article/f48430cfb98944a782474642602a6f0c