Zobrazeno 1 - 10
of 87
pro vyhledávání: '"QP517"'
Publikováno v:
FEBS Letters. 596:762-771
Calmodulin is a conserved calcium signalling protein that regulates a wide range of cellular functions. Amino-terminal acetylation is a ubiquitous post-translational modification that affects the majority of human proteins, to stabilise structure, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d15650e58876f47ee91152b91b0b81
https://doi.org/10.1002/1873-3468.14304
https://doi.org/10.1002/1873-3468.14304
Publikováno v:
Biochemical Journal
The divalent anion sodium symporter (DASS) family of transporters (SLC13 family in humans) are key regulators of metabolic homeostasis, disruption of which results in protection from diabetes and obesity, and inhibition of liver cancer cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175e60252896649a1530256f72da0e7f
http://europepmc.org/articles/PMC8652582
http://europepmc.org/articles/PMC8652582
Publikováno v:
The Journal of Biological Chemistry
The divalent anion sodium symporter (DASS) family (SLC13) plays critical roles in metabolic homeostasis, influencing many processes, including fatty acid synthesis, insulin resistance, and adiposity. DASS transporters catalyze the Na+-driven concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa49ce44ea9743d1ca8284864657eac
https://doi.org/10.1074/jbc.ra120.013894
https://doi.org/10.1074/jbc.ra120.013894
Autor:
David B. Sauer, Jennifer J. Marden, Joseph C. Sudar, Jinmei Song, Christopher Mulligan, Da-Neng Wang
The Na+-dependent dicarboxylate transporter from Vibrio cholerae (VcINDY) is a prototype for the divalent anion sodium symporter (DASS) family. While the utilization of an electrochemical Na+ gradient to power substrate transport is well established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d1354307898ea99c42ba34c4eb3349
https://kar.kent.ac.uk/95499/1/s41467-022-30406-4.pdf
https://kar.kent.ac.uk/95499/1/s41467-022-30406-4.pdf
Publikováno v:
Biomolecular Concepts, Vol 11, Iss 1, Pp 102-115 (2020)
Atomic force microscopy, AFM, is a powerful tool that can produce detailed topographical images of individual nano-structures with a high signal-to-noise ratio without the need for ensemble averaging. However, the application of AFM in structural bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16dba4583b89d0b5b33703f38c5c5fa
https://doi.org/10.1515/bmc-2020-0009
https://doi.org/10.1515/bmc-2020-0009
Autor:
Emiel Michiels, Patricia Guerreiro, Yulia Lampi, Frederic Rousseau, Bert Houben, Joris de Wit, Meine Ramakers, Katerina Konstantoulea, Luís Ribeiro, Liam D. Aubrey, Nikolaos N. Louros, Joost Schymkowitz, Wei-Feng Xue, Matthias De Vleeschouwer
Publikováno v:
EMBO J
It is still unclear why pathological amyloid deposition initiates in specific brain regions or why some cells or tissues are more susceptible than others. Amyloid deposition is determined by the self-assembly of short protein segments called aggregat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9892406fea6d2a2bf3600469d2001645
https://lirias.kuleuven.be/handle/20.500.12942/687769
https://lirias.kuleuven.be/handle/20.500.12942/687769
Autor:
Chloe A. Johnson, Cecilia Ferrantini, Michael A. Geeves, Corrado Poggesi, Chiara Tesi, Jonathan Walklate
Publikováno v:
Cell Mol Life Sci
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Human atrial and ventricular contractions have distinct mechanical characteristics including speed of contraction, volume of blood delivered and the range of pressure generated. Notably, the ventricle expresses predominantly β-cardiac myosin while t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e6405a43c257065f1790f9e45c32bd
Maintaining membrane integrity is of paramount importance to the survival of bacteria as the membrane is the site of multiple crucial cellular processes including energy generation, nutrient uptake and antimicrobial efflux. The DedA family of integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5eaf46c028b65a31875e49b900f3d3a
https://doi.org/10.1101/2021.10.18.464800
https://doi.org/10.1101/2021.10.18.464800
The prediction of highly ordered three-dimensional structures of amyloid protein fibrils from the amino acid sequences of their monomeric self-assembly precursors constitutes a challenging and unresolved aspect of the classical protein folding proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae837c685856c4b627c692259f83db9
Publikováno v:
Biochemical Society Transactions. 47:425-432
Spermatogenesis is central to successful sexual reproduction, producing large numbers of haploid motile male gametes. Throughout this process, a series of equational and reductional chromosome segregation precedes radical repackaging of the haploid g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad523cbd81795ef98fc1c0e71c9a8459
https://doi.org/10.1042/bst20180231
https://doi.org/10.1042/bst20180231