Zobrazeno 1 - 10 of 240 pro vyhledávání: '"QH345"'
1
Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1
Autor: Vasiliki Lazou, Bethan Medina-Pritchard, A. Arockia Jeyaprakash, Juan Zou, Juri Rappsilber, Olwyn Byron, Patrick Heun, Maria Alba Abad
Publikováno v: Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad Fernandez, M, Rappsilber, J, Heun, P & Arulanandam, J 2020, ' Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1 ', EMBO Journal . https://doi.org/10.15252/embj.2019103234
The EMBO Journal
Centromeres are microtubule attachment sites on chromosomes defined by the enrichment of histone variant CENP‐A‐containing nucleosomes. To preserve centromere identity, CENP‐A must be escorted to centromeres by a CENP‐A‐specific chaperone f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f15250d7da65c2aba8a1b7ffdd68ec8
https://eprints.gla.ac.uk/236338/1/236338.pdf
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2
Substrate specificity of the neutral sphingomyelinase from Trypanosoma brucei
Autor: Terry K. Smith, Emily A. Dickie, Simon A. Young
This work was supported primarily through the European Community’s Seventh Framework Programme under grant agreements no. 602773 (Project KINDRED), with additional support from Wellcome Trust Project grant (086658); Medical Research Council (MR/M02
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806e946f4f899b7dbe328484b386e963
https://eprints.gla.ac.uk/197303/7/197303.pdf
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3
Dissertation/ Thesis
Design, synthesis and evaluation of a molecular probe for ligand-based receptor capture targeting membrane receptors
Autor: Müskens, Frederike Maximiliane
Membrane proteins are vital to drug discovery, being targeted by some 60% of the currently marketed therapeutic medicines, with more than half of those targeting transmembrane receptors. Identification of transmembrane receptor targets of poorly char
Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.768732
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4
Dissertation/ Thesis
The biochemical and biophysical characterisation of protein antibiotics targeting Pectobacterium spp. and Streptococcus agalactiae
Autor: Thompson, Catriona M. A.
Food security is the idea by which a population has enough food to sustain itself without famine. A large number of factors can influence the stability of food production, including diseases caused by microorganisms. Pectobacterium spp. is one of the
Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.768754
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5
Investigation of the DNA damage in haematopoiesis using CRISPR/Cas9 technology
Autor: Sarrou, Evgenia
Publikováno v: IndraStra Global.
DNA replication is a highly regulated process that ensures the faithful duplication of the genome. However, endogenous or exogenous factors, such as limited DNA replication components and chemotherapeutic drugs, respectively, can cause defects in its
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a8c976b1b5a00a2250f40255ed0d67
https://igi.indrastra.com/items/show/231925
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6
The biochemical and biophysical characterisation of protein antibiotics targeting Pectobacterium spp. and Streptococcus agalactiae
Autor: Thompson, Catriona M.A.
Publikováno v: IndraStra Global.
Food security is the idea by which a population has enough food to sustain itself without famine. A large number of factors can influence the stability of food production, including diseases caused by microorganisms. Pectobacterium spp. is one of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d55077277b66cceecfba0525ee652b2
http://theses.gla.ac.uk/41021/7/2019ThompsonPhD.pdf
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8
The effects of experimental hyperglycaemia and hyperinsulinaemia on macrovascular endothelial cell function
Autor: Strembitska, Anastasiya
Publikováno v: IndraStra Global.
Endothelial dysfunction, characterised by decreased NO synthesis, is associated with an increased risk of cardiovascular complications in patients with type 1 diabetes mellitus, type 2 diabetes mellitus (T2DM) and insulin resistance. The dysfunctiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47aff7c1de7cdbd9e3536495112b5cfd
https://igi.indrastra.com/items/show/231869
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9
Identification and characterisation of cell intrinsic mechanisms regulating intestinal stem cell behaviour during acute damage
Autor: Carroll, Lynsey Rose
The maintenance and regeneration of tissues and organs is essential to ensure the health of an organism and its survival. These processes are characteristics of self-renewing tissues and are typically undertaken by dedicated stem cells. Therefore, un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e5bf653d826cc04bca8b2d7add196c
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10
Role of tryptophans in UVR8 photoreceptor function in arabidopsis
Autor: Díaz Ramos, Lourdes Aranzazú
Plants are exposed to a variety of environmental cues that can affect their development. Of these, light is the most important as apart from being their energy source, it also serves as an informational cue that will allow them to control a range of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0165c59eecec4d55ca7aea0eb9e6c6
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