YPIBP: A repository for phosphoinositide-binding proteins in yeast

Autor: Yan Yuan Tseng, Wei Sheng Wu, Chien Sheng Chen, Biqing Liang, Jagat Rathod, Han-Chen Yen

Publikováno v: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3692-3707 (2021)

Graphical abstract
Highlights • YPIBP contains 679 PI-binding yeast proteins and their PI-binding evidence. • YPIBP contains 181 lipid-binding domains and 103 lipid-related domains. • YPIBP provides PI-binding enrichment analysis and domai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb2a67a1c3142c2aef0b9fab10457ce
https://pubmed.ncbi.nlm.nih.gov/34285772

Performance of a whole-body human dust inhalation challenge exposure chamber

Autor: Yehia Y. Hammad, Luis F. Pieretti

Publikováno v: Toxicology Reports
Toxicology Reports, Vol 5, Iss, Pp 793-799 (2018)

Background: Evaluation of the performance of a whole-body human dust exposure chamber is presented in this report. Methods: The volume of the chamber is 2.13 m3 and it is operated at a flow rate of 1.0 m3/min. Makeup and exhaust air were filtered. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbb6dffc852796a8d3be1caf8afb6e2
https://doi.org/10.1016/j.toxrep.2018.07.004

Advances in ligase chain reaction and ligation-based amplifications for genotyping assays: Detection and applications

Autor: Abdullah A.Y. Gibriel, Ola Adel

Publikováno v: Mutation Research. Reviews in Mutation Research

Genetic variants have been reported to cause several genetic diseases. Various genotyping assays have been developed for diagnostic and screening purposes but with certain limitations in sensitivity, specificity, cost effectiveness and/or time saving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c481b868fa2e6cb68bb79e979fc397ab
https://doi.org/10.1016/j.mrrev.2017.05.001

Building-block architecture of botulinum toxin complex: Conformational changes provide insights into the hemagglutination ability of the complex

Autor: Akihito Yamano, Yoshimasa Sagane, Takashi Matsumoto, Kimiko Hasegawa, Koichi Niwa, Toshihiro Watanabe, Tomonori Suzuki

Publikováno v: Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 67-71 (2017)
Biochemistry and Biophysics Reports

Clostridium botulinum produces the botulinum neurotoxin (BoNT). Previously, we provided evidence for the “building-block” model of botulinum toxin complex (TC). In this model, a single BoNT is associated with a single nontoxic nonhemagglutinin (N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95192af97f303a13476616894b16235f
http://www.sciencedirect.com/science/article/pii/S2405580816302965

An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3

Autor: Yasuharu Shinoda, Yasushi Yabuki, Yuki Aoyama, Naoya Fukui, Hanae Yamamoto, Kohji Fukunaga, Tomohiro Mizobata, Ichiro Kawahata, Yasushi Kawata, Kunihiro Hongo, Moe Miyabe

Publikováno v: The Journal of Biological Chemistry
Fukui, Naoya. Yamamoto, Hanae. Miyabe, Moe. et al. An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3. Journal of Biological Chemistry. 296, 100663. 2021-04-20.

α-synuclein (αSyn) is a protein known to form intracellular aggregates during the manifestation of Parkinson’s disease. Previously, it was shown that αSyn aggregation was strongly suppressed in the midbrain region of mice that did not possess th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f65c094ec9071bc126830bb84c2b90b
https://doi.org/10.1016/j.jbc.2021.100663