Zobrazeno 1 - 10
of 180
pro vyhledávání: '"QC, quality control"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 23, Iss, Pp 44-49 (2022)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • Mass spectrometry produces data which can be used to monitor instrument performance. • We describe a tool that parses and visualizes mass spectrometry data. • This toolkit can be applied to increase quality control for a complex LC
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 7, Pp 699-705 (2021)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Full disintegration of Oral solid dosage forms is critically important to achieve reliable clinical performance of the drug. Tablets/capsules are supposed to be taken with a full glass of water; however, many patients do not follow this recommendatio
Autor:
Shaheen Akhtar, Joanna Bottomley, Edward Ryder, Daniel M Barrett, Michaela Bruntraeger, Sanger Mouse Genetics, James Bussell, Jonathan Burvill, Radka Platte, Debarati Sethi, Diane Gleeson
Publikováno v:
Methods (San Diego, Calif.)
Highlights • Next generation sequencing is a scalable solution to genotyping mutant mice. • Ratios of wild type and mutant sequence counts are used to call the genotype. • Hundreds of samples can be multiplexed into one sequencing experiment.
Akademický článek
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Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Graphical abstract
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 1-10 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • Analysis of 2-methylcitric acid, methylmalonic acid, and homocysteine in DBS. • A dual derivatization LC-MS/MS strategy developed for use in second-tier NBS. • Second-tier panel replaces multiple initial follow-up tests. • Improv
Autor:
William W. L. Cheung, Debajyoti Chowdhury, Zhenmiao Zhang, Zhaoxiang Bian, Aiping Lu, Chao Yang, Lu Zhang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6301-6314 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Metagenomic sequencing provides a culture-independent avenue to investigate the complex microbial communities by constructing metagenome-assembled genomes (MAGs). A MAG represents a microbial genome by a group of sequences fro
Metagenomic sequencing provides a culture-independent avenue to investigate the complex microbial communities by constructing metagenome-assembled genomes (MAGs). A MAG represents a microbial genome by a group of sequences fro
Autor:
Sabine Kasimir-Bauer, Harvey I. Pass, Carlos R. Oliveira, Jeffrey S. Weber, Joanna Roder, Julia Grigorieva, Senait Asmellash, Lelia Net, Heinrich Roder, Krista Meyer
Publikováno v:
Clinical Mass Spectrometry
Highlights • Biological process-associated scores generated from mass spectrometry of serum. • Scores demonstrated acceptable levels of reproducibility. • Scores associated with biological processes and clinical outcome in cancer patients. •
Autor:
Zhuowei Liu, Yuxi Wang, Chengjian Zhao, Yang Zhang, Manyu Zhao, Jinliang Yang, Yuqin Yao, Peng Li, Chen Zhengxia, Xiaoxin Chen, Chaofeng Long
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1453-1475 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1453-1475 (2020)
Angiokinases, such as vascular endothelial-, fibroblast- and platelet-derived growth factor receptors (VEGFRs, FGFRs and PDGFRs) play crucial roles in tumor angiogenesis. Anti-angiogenesis therapy using multi-angiokinase inhibitor has achieved great