Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Q. F. Ahkong"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1558(1):1-13
Poly(ethylene glycol)-lipid (PEG-lipid) conjugates are widely used in the field of liposomal drug delivery to provide a polymer coat that can confer favorable pharmacokinetic characteristics on particles in the circulation. More recently these lipids
Publikováno v:
Molecular Membrane Biology. 15:1-14
Polymeric, nucleic acid drugs must be protected from endogenous nucleases and delivered to target cell nuclei in order to maximize their activity. Constructs expressing therapeutic genes, antisense oligonucleotides and ribozymes can be delivered into
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1148:30-38
We have previously reported that acidic phospholipids are exposed at the surface of human erythrocytes when the cells are subjected to electrical breakdown. It has now been shown that the prothrombinase assay, which was used previously for the determ
Publikováno v:
Biochimica et biophysica acta. 1065(1)
There are many reports of hemi-fusion in phospholipid vesicles but few published studies on hemi-fusion in cells. We report evidence from both fluorescence microscopy and freeze-fracture electron microscopy for hemi-fusion in the electrofusion of hum
Publikováno v:
FEBS Letters. 95:147-152
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 689:548-560
Poly(ethylene glycol) 6000 induced a concentration-dependent, time-dependent decrease in the latency of the reaction between Arsenazo III sequestered in liposomes and extraliposomal Ca 2+ . This was mediated by a gross change in liposomal permeabilit
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 692:109-114
Preparations of poly(ethylene glycol) 6000 (PEG) from five different commercial sources have been purified, and their ability to fuse hen erythrocytes has been investigated. Quantitative assessments of cell fusion showed that before purification one
Autor:
Q. F. Ahkong, Jack A. Lucy
Publikováno v:
Journal of Cell Science. 91:597-601
Factors that govern the experimentally induced fusion of erythrocytes with one another may generally be relevant to whether or not osmotic forces drive membrane fusion in exocytosis because, under appropriate conditions, osmotic swelling can drive th
Publikováno v:
Journal of Cell Science. 88:389-398
It has been claimed that purified poly(ethylene glycol) (PEG) is able only to aggregate cells and not to fuse them. In our hands, purified PEG 6000 (recrystallized/dialysed) induces both aggregation and fusion of human erythrocytes, and the mechanism
Publikováno v:
Biochemical Journal. 176:159-167
1. The fusion of human erythrocytes into multicellular bodies that is induced by microdroplets of oleoylglycerol was investigated by optical and electron microscopy, and by gel electrophoresis of membrane proteins. 2. At the highest concentrations of