Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Q. Barry"'
Autor:
Robert Blelloch, Emmanuelle Passegué, Scott C. Kogan, Haijiang Lin, Keegan Q. Barry-Holson, Cassandra D. Belair, Deepa Subramanyam
Supplementary Figures 1-7 from PML-RARα and Dnmt3a1 Cooperate in vivo to Promote Acute Promyelocytic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bda3dd13e9777c651d3c4fd9b467fd
https://doi.org/10.1158/0008-5472.22382241
https://doi.org/10.1158/0008-5472.22382241
Autor:
Robert Blelloch, Emmanuelle Passegué, Scott C. Kogan, Haijiang Lin, Keegan Q. Barry-Holson, Cassandra D. Belair, Deepa Subramanyam
The PML-RARα oncogene is the central effector of acute promyelocytic leukemia (APL). PML-RARα physically interacts with epigenetic-modifying enzymes including DNA methyltransferases (Dnmt) to suppress critical downstream targets. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f76f58a47ea9a06dfafd568be1f6436
https://doi.org/10.1158/0008-5472.c.6500139.v1
https://doi.org/10.1158/0008-5472.c.6500139.v1
Autor:
Trevor Simard, Marino Labinaz, Christopher Glover, Derek So, Cole R Clifford, Aun-Yeong Chong, Alexander Dick, Alyssa Chow, Q. Barry, Rene Boudreau, Michael Froeschl, U. Tran, Benjamin Hibbert, A. Fu, Michel R. Le May, Juan J Russo
Publikováno v:
The American Journal of Cardiology. 161:19-25
The optimal length of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) remains debated. Current guidelines recommend individualized treatment with consideration of risk scores. We sought to evaluate the degree of agreem
Autor:
Derek So, Nikita Malhotra, Nathan Orr, Cole R Clifford, Q. Barry, Sarah Visintini, Rene Boudreau, A. Fu
Publikováno v:
European Heart Journal - Cardiovascular Pharmacotherapy. 8:511-518
Aims The PRECISE-DAPT (Predicting Bleeding Complication in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy) score identifies patients at high risk of bleeding complications following percutaneous coronary intervention
Autor:
Derek So, Q. Barry, Alexander Dick, Juan J Russo, Trevor Simard, Michael Froeschl, Christopher Glover, Marino Labinaz, Cole R Clifford, Benjamin Hibbert, Alyssa Chow, Angel Fu, Rene Boudreau, Michel R. Le May, Aun-Yeong Chong
Publikováno v:
CJC Open, Vol 3, Iss 9, Pp 1091-1099 (2021)
CJC Open
CJC Open
Background: De-escalation from potent platelet P2Y12 inhibitors to clopidogrel is common. Despite having a clinical rationale, non-bleeding-related de-escalation when a lateral change between potent agents is an option may put patients at increased i
Autor:
Cole R Clifford, Michel R. Le May, Alyssa Chow, Rene Boudreau, Derek So, Q. Barry, A. Fu, Aun-Yeong Chong
Publikováno v:
CJC Open, Vol 3, Iss 5, Pp 565-573 (2021)
CJC Open
CJC Open
Background Management of ST-elevated myocardial infarction (STEMI) necessitates rapid reperfusion. Delays prolong myocardial ischemia and increase the risk of complications, including death. The COVID-19 pandemic may have impacted STEMI management. W
Autor:
A Fu, Q Barry, R Boudreau, C Clifford, A Chow, T Simard, A Y Chong, A Dick, M Froeschl, C Glover, B Hibbert, M Labinaz, M Le May, J Russo, D So
Publikováno v:
European Heart Journal. 42
Background Patients with high bleeding risk characteristics (HBR) presenting with acute coronary syndrome (ACS) pose a clinical challenge to balance risk for recurrent ischemic events versus incurring bleeding with dual antiplatelet therapy. Purpose
Autor:
M. Le May, L Labinaz, Q. Barry, Christopher Glover, Benjamin Hibbert, U. Tran, Trevor Simard, Alexander Dick, D Perry-Nuygen, Michael Froeschl, Rene Boudreau, Derek Yiu Fai So, Aun-Yeong Chong, A. Fu
Publikováno v:
European Heart Journal. 41
Background Dual antiplatelet therapy (DAPT) is the standard of care following PCI. DAPT reduces ischemic events but increases bleeding risk. Duration of DAPT following PCI remains controversial. Current guidelines recommend duration be individualized
Autor:
Rene Boudreau, Dylan Perry-Nguyen, A. Fu, Aun-Yeong Chong, Q. Barry, T Simmard, Alexander Dick, Michael Froeschl, Marino Labinaz, M. Le May, Derek Yiu Fai So, Christopher Glover, U. Tran, Benjamin Hibbert
Publikováno v:
European Heart Journal. 40
Background Dual antiplatelet therapy (DAPT), with aspirin and a P2Y12 inhibitor, is the standard therapy for patients following PCI. Duration of treatment with DAPT has been controversial despite large studies. Current guidelines recommend treatment
Publikováno v:
Histopathology. 68:119-137
Since the discovery of breast cancer stem cells (BCSCs) more than 10 years ago, a body of exciting research has developed. The intrinsic properties of BCSCs, including self-renewal and the ability to give rise to heterogeneous progeny, make BCSCs a l