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pro vyhledávání: '"Pyruvamide"'
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Publikováno v:
Tetrahedron. 59:8245-8249
—The design, synthesis and evaluation of a pentacyclic scaffold, CWO-324 to mimic saframycin A is described. CWO-324 isreadily synthesized in five steps from 1,4-diacetyl-piperazine-2,5-dione and 2,5-dimethoxybenzaldehyde. CWO-324 was found to sci
Publikováno v:
Tetrahedron. 53:13739-13748
The addition of water or alcohol to 3-halopyruvamides, having a special interest in enzymology, permitted us to isolate stable α-diols and hemiketals, until then detected only by spectroscopic means. The reaction is not diastereoselective, but selec
Publikováno v:
Tetrahedron: Asymmetry. 8:2133-2140
Pyruvamide and its N-alkylated derivatives have been synthesised and hydrogenated enantioselectively to the corresponding alcohols over an alumina-supported Pt catalyst chirally modified by adsorbed cinchonidine. Depending on the substrate structure
Autor:
Helmut Feistauer, Richard Neidlein
Publikováno v:
Helvetica Chimica Acta. 79:895-912
Syntheses of 2,3-Dioxoalkylphonates and Other Novel β-Ketophosphonates As Well As of a Phosphinopyruvamide ( = (Alkyloxyphosphinyl)pyruvamide) The new 3-(diethoxyphosphoryl)-2-oxopropanoates 5 and 6 and -propanamides 1–4 with various amino substit
Autor:
Laurent Gatay, Thomas Colin, Laurent El Kaim, Valerie Michaut, Laetitia Gaultier, Laurence Grimaud
Publikováno v:
Tetrahedron Letters. 37:375-378
Hydrates of trifluoropyruvamides are readily obtained from isocyanides and trifluoroacetic anhydride. Under catalysis with secondary amines, these hydrates were successfully reacted with various methylketones to form fluorinated aldol type compounds.
Autor:
Yong Hae Kim, Il Suk Byun
Publikováno v:
Synthetic Communications. 25:1963-1969
Both pyruvamide and benzoylformamide having (S)-2-methoxy-methylindoline as a chiral auxiliary were reduced with various reducing agents in high stereoselectivities (up to dr = 99 : 1).
Publikováno v:
Tetrahedron. 51:8213-8230
A synthetic strategy for the preparation of the isoquinolinequinone antibiotic safracin A ( 1a ) is outlined. Our initial strategy for the construction of the ABC ring was based on a retrosynthetic analysis. Conversion of 5 in five steps to the imide
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 24