Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pyrrolidines/chemistry"'
Autor:
Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G.N., Jones, Chelsea R., Vermeulen, Bram J.A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A.M., Bonvin, Alexandre M.J.J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus, Sub NMR Spectroscopy, Sub Membrane Biochemistry & Biophysics, Sub Cell Biology, NMR Spectroscopy, Celbiologie, Membrane Biochemistry and Biophysics
Publikováno v:
Nature, 608(7922), 390. Nature Research
Nature
Nature, 608(7922), 390-396. Nature Publishing Group
Nature
Nature, 608(7922), 390-396. Nature Publishing Group
Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance1–3. Teixobactin4 represents a new class of antibiotics with a unique chemical scaffold and lack of detectable resistance. Teixobactin targets lipid II, a precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a758c21eadc4b4daf2806d5db5df77
https://doi.org/10.1038/s41586-022-05019-y
https://doi.org/10.1038/s41586-022-05019-y
Autor:
Emilia Păunescu, Elisabeth Mouray, Patricia Melnyk, R. A. Varga, Philippe Grellier, E. Boll, S. Susplugas
Publikováno v:
Medicinal Chemistry
Medicinal Chemistry, Bentham Science Publishers, 2008, 4 (5), pp.405-427. ⟨10.2174/157340608785700153⟩
Medicinal Chemistry, Bentham Science Publishers, 2008, 4 (5), pp.405-427. ⟨10.2174/157340608785700153⟩
International audience; Amodiaquine remains one of the most prescribed antimalarial 4-aminoquinoline. To assess the importance of the 4'-hydroxyl group and subsequent hydrogen bond in the antimalarial activity of amodiaquine (AQ), a series of new ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eae846d114100c5db132d3cb4c4abf
https://pubmed.ncbi.nlm.nih.gov/18782038
https://pubmed.ncbi.nlm.nih.gov/18782038
Publikováno v:
Journal of Pharmaceutical Sciences, Vol. 96, No 1 (2007) pp. 84-92
The goal was to explore whether the incorporation of antinucleant polymers into a testosterone spray formulation could stabilize a putative supersaturated state and improve the delivery of the drug across the skin. Several antinucleants were screened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af3e87524d98d3a95c501243bb664b2
https://pubmed.ncbi.nlm.nih.gov/16998787
https://pubmed.ncbi.nlm.nih.gov/16998787
Autor:
Nathalie Chamond, Wim Degrave, Paola Minoprio, Alejandro Buschiazzo, Christophe Grégoire, Pedro M. Alzari, Armand Berneman, Nicolas Coatnoan, Maira Goytia, William Shepard, Alain Cosson, Francis Schaeffer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩
Amino acid racemases catalyze the stereoinversion of the chiral C α to produce the d -enantiomers that participate in biological processes, such as cell wall construction in prokaryotes. Within this large protein family, bacterial proline racemases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a56dabd710838c99f8ce668bd10bbe
https://hal.archives-ouvertes.fr/hal-02523212
https://hal.archives-ouvertes.fr/hal-02523212
