Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pyramidal Cells/drug effects"'
Autor:
Yannis Dalezios, Francesco Ferraguti, Ryuichi Shigemoto, Marco Capogna, Peter Somogyi, Naoki Kogo
Publikováno v:
Kogo, N, Dalezios, Y, Capogna, M, Ferraguti, F, Shigemoto, R & Somogyi, P 2004, ' Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat ', The European journal of neuroscience, vol. 19, no. 10, pp. 2727-40 . https://doi.org/10.1111/j.0953-816X.2004.03394.x
The release of GABA in synapses is modulated by presynaptic metabotropic glutamate receptors (mGluRs). We tested whether GABA release to identified hippocampal neurons is influenced by group III mGluR activation using the agonist L-(+)-2-amino-4-phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85919f3a95f9d44365dd61e823b151ac
https://ora.ox.ac.uk/objects/uuid:456fde59-fa6c-4f47-9625-3967a8b29607
https://ora.ox.ac.uk/objects/uuid:456fde59-fa6c-4f47-9625-3967a8b29607
Autor:
Dominique Muller, Laszlo Vutskits, Adrian Briner, Mathias De Roo, Walid Habre, Alexandre Dayer
Publikováno v:
Anesthesiology
Anesthesiology, Vol. 112, No 3 (2010) pp. 546-556
Anesthesiology, Vol. 112, No 3 (2010) pp. 546-556
Background Recent experimental observations suggest that, in addition to induce neuroapoptosis, anesthetics can also interfere with synaptogenesis during brain development. The aim of this study was to pursue this issue by evaluating the exposure tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ce26a828e798c3856486bb6f70d61d
https://doi.org/10.1097/aln.0b013e3181cd7942
https://doi.org/10.1097/aln.0b013e3181cd7942
Autor:
Elli Leppä, Peer Wulff, Waltraud Ogris, Marco Capogna, Peter Somogyi, H. Hoeger, Esa R. Korpi, Anni-Maija Linden, William Wisden, Werner Sieghart, A. Oberto, C. Halbsguth, Theofanis Karayannis, D. W. Cope, Francesco Ferraguti
Publikováno v:
Cope, D W, Halbsguth, C, Karayannis, T, Wulff, P, Ferraguti, F, Hoeger, H, Leppä, E, Linden, A-M, Oberto, A, Ogris, W, Korpi, E R, Sieghart, W, Somogyi, P, Wisden, W & Capogna, M 2005, ' Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation ', The European journal of neuroscience, vol. 21, no. 11, pp. 3002-16 . https://doi.org/10.1111/j.1460-9568.2005.04127.x
Europe PubMed Central
Europe PubMed Central
Zolpidem is a hypnotic benzodiazepine site agonist with some gamma-aminobutyric acid (GABA)(A) receptor subtype selectivity. Here, we have tested the effects of zolpidem on the hippocampus of gamma2 subunit (gamma2F77I) point mutant mice. Analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a0e4e690a4883f85a630b50b1ff98
https://doi.org/10.1111/j.1460-9568.2005.04127.x
https://doi.org/10.1111/j.1460-9568.2005.04127.x
Autor:
Rob Willemsen, Andreea S. Pop, Celine de Esch, Tracy Li, Josien Levenga, Aaron Isaacs, Ingeborg M. Nieuwenhuizen, Fabrizio Gasparini, Ben A. Oostra, Ronald A.M. Buijsen
Publikováno v:
Psychopharmacology, 231(6), 1227-35. Springer
Psychopharmacology, 231(6), 1227-1235. Springer-Verlag
Psychopharmacology, 231(6), 1227-1235. Springer-Verlag
Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and autism. The disease is a result of lack of expression of the fragile X mental retardation protein. Brain tissues of patients with FXS and mice with FMRP deficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a6cc22f1129b927b73d36a8aa16ba5
https://cris.maastrichtuniversity.nl/en/publications/d5dbf5aa-af34-436e-8f46-13ad6e5e63b7
https://cris.maastrichtuniversity.nl/en/publications/d5dbf5aa-af34-436e-8f46-13ad6e5e63b7
Publikováno v:
The Journal of Physiology, Vol. 515 ( Pt 3) (1999) pp. 769-776
1. Whole-cell clamp recordings of the compound synaptic current elicited by afferent stimulation of Schaffer collaterals showed that blockade of the NMDA, AMPA and GABAA receptor-mediated components by 6-nitro-7-sulphamoyl- benzo(f)quinoxaline-2,3-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b12fb856d9540dae58e1ea441a12e25
https://doi.org/10.1111/j.1469-7793.1999.769ab.x
https://doi.org/10.1111/j.1469-7793.1999.769ab.x
INTRODUCTION: The hippocampus is an important region of the brain that regulates cognitive and emotional functions. In this study, we examined the impact of perinatal administration of testosterone propionate (TP) on the number of pyramidal neurons i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::5e5c25625923f29710852a9680316496
Publikováno v:
Price, C J, Scott, R, Rusakov, D A & Capogna, M 2008, ' GABA(B) receptor modulation of feedforward inhibition through hippocampal neurogliaform cells ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 28, no. 27, pp. 6974-82 . https://doi.org/10.1523/JNEUROSCI.4673-07.2008
Feedforward inhibition of neurons is a fundamental component of information flow control in the brain. We studied the roles played by neurogliaform cells (NGFCs) of stratum lacunosum moleculare of the hippocampus in providing feedforward inhibition t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7c26b01c99e9c52b34d8fcce7aad7f
http://ora.ox.ac.uk/objects/uuid:a6b6a981-6d63-47fc-a846-312166449b11
http://ora.ox.ac.uk/objects/uuid:a6b6a981-6d63-47fc-a846-312166449b11
Publikováno v:
Europe PubMed Central
This study was designed to evaluate the penicillin-induced epilepsy model in terms of dose-response relationship of penicillin used to induce epilepsy seizure on hippocampal neuron number and hippocampal volume in Sprague-Dawley rats. Seizures were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a39262d3f568a76f3ed1f74981389cd8
Action of tachykinins in the hippocampus: facilitation of inhibitory drive to GABAergic interneurons
Publikováno v:
Neuroscience, Vol. 156, No 3 (2008) pp. 527-36
By acting on neurokinin 1 (NK1) receptors, neuropeptides of the tachykinin family can powerfully excite rat hippocampal GABAergic interneurons located in the CA1 region and by this way indirectly inhibit CA1 pyramidal neurons. In addition to contact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92054f57903cbffc2fe46ef8d18992fe
https://archive-ouverte.unige.ch/unige:1687
https://archive-ouverte.unige.ch/unige:1687
Publikováno v:
Elfant, D, Pál, B Z, Emptage, N & Capogna, M 2008, ' Specific inhibitory synapses shift the balance from feedforward to feedback inhibition of hippocampal CA1 pyramidal cells ', The European journal of neuroscience, vol. 27, no. 1, pp. 104-13 . https://doi.org/10.1111/j.1460-9568.2007.06001.x
Feedforward and feedback inhibition are two fundamental modes of operation widespread in the nervous system. We have functionally identified synaptic connections between rat CA1 hippocampal interneurons of the stratum oriens (SO) and interneurons of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::53cea25904a0f8bf3582b38d27192eab