Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pyotr Kisselev"'
Autor:
Vladimir A. Khripach, Aliaksei R. Sysa, Vladimir N. Zhabinskii, Pyotr Kisselev, Marina V. Anisovich, Olesya V. Panibrat
Publikováno v:
Steroids. 117:11-15
To explore the underlying mechanism of cancer cell growth inhibition by brassinosteroids (BS), reactive oxygen species (ROS) generation under treatment with 28-homocastasterone and its synthetic derivatives (22S,23S)-28-homocastasterone was measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82beaef73c1d275d41f00280b9061685
https://doi.org/10.1016/j.steroids.2016.06.010
https://doi.org/10.1016/j.steroids.2016.06.010
Publikováno v:
Cancer Research. 65:2972-2978
Several epidemiologic studies associate certain CYP1A1 genotypes, alone or in combination, with an increased risk of estrogen-related cancers. To answer the question of whether genotype-dependent activation of estrogens by CYP1A1 could be the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28149041d3b767b69c68700ce3fd203
https://doi.org/10.1158/0008-5472.can-04-3543
https://doi.org/10.1158/0008-5472.can-04-3543
Autor:
Spencer S. Ericksen, Horst Honeck, Dieter Schwarz, Pyotr Kisselev, Wolf-Hagen Schunck, Grazyna D. Szklarz, Alexey Chernogolov, Ivar Roots
Publikováno v:
Biochemical Pharmacology. 67:1445-1457
Human cytochrome P450 1A1 (CYP1A1) and human NADPH-cytochrome P450 reductase were expressed and purified from Spodoptera frugiperda insect cells. A reconstituted enzymatically active system metabolized polyunsaturated fatty acids such as arachidonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc66a55428e5d58aea4624e9b95d2f47
https://doi.org/10.1016/j.bcp.2003.12.023
https://doi.org/10.1016/j.bcp.2003.12.023
Publikováno v:
Xenobiotica. 31:345-356
1. Three human cytochrome P4501A1 (CYP1A1) variants, wild-type (CYP1A1.1), CYP1A1.2 (1462V) and CYP1A1.4 (T461N), were co-expressed with human NADPH-P450 reductase (OR) in Spodoptera frugiperda (Sf9) insect cells by baculovirus co-infection to elabor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8497c0f0f3ff0a90fc40575e01df7ae7
https://doi.org/10.1080/00498250110055947
https://doi.org/10.1080/00498250110055947
Autor:
Pyotr Kisselev, Rolf D. Schmid, Uwe T. Bornscheuer, Sandra Pisch, Wolfgang Pfeil, Dieter Schwarz
Publikováno v:
Biochemistry. 36:14262-14270
To analyze whether specific protein-lipid interactions or physical features of the membrane contribute to cytochrome P450SCC (CYP11A1) activation by lipids, dimyristoylphosphatidylcholine/cardiolipin and dimyristoylphosphatidylcholine/branched phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aabd428b4010449a1f46f0a43848ed0
https://doi.org/10.1021/bi9714262
https://doi.org/10.1021/bi9714262
Publikováno v:
Chemistry and Physics of Lipids. 85:91-99
Phosphatidylcholines with saturated branched fatty acyl chains substituted in the 2-positions of the main chains have a significant stimulating effect on both the side chain cleavage activity of cytochrome P450SCC and the ability of P450SCC to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9db72341bd453d72cd941ad4bb22b6e
https://doi.org/10.1016/s0009-3084(96)02642-4
https://doi.org/10.1016/s0009-3084(96)02642-4
Publikováno v:
Journal of Biological Chemistry. 271:12840-12846
Cardiolipin has been shown to be the most effective activator of cholesterol side chain cleavage activity of cytochrome P450SCC, and evidence has been provided for a lipid effector site on the enzyme. Results suggested the headgroup of cardiolipin as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e76fc76d6edcdf08dbc61d3b383f386
https://doi.org/10.1074/jbc.271.22.12840
https://doi.org/10.1074/jbc.271.22.12840
Publikováno v:
Biochimica et biophysica acta. 1814(1)
Several epidemiological studies associate certain CYP1A1 genotypes, alone or in combination, with an increased risk of estrogen-related cancers. Previously we demonstrated that metabolic activation of estrogens by CYP1A1 is a genotype-dependent react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4521439d30adafc430eb61a9b8fd6102
https://pubmed.ncbi.nlm.nih.gov/20883830
https://pubmed.ncbi.nlm.nih.gov/20883830
Publikováno v:
Biochemical and biophysical research communications. 336(3)
To answer the question whether the most common allelic variants of human CYP1A1, namely CYP1A1.1 (wild type), CYP1A1.2 (Ile462Val), and CYP1A1.4 (Thr461Asn), differ in their catalytic activity towards eicosapentaenoic acid (EPA), in vitro enzymatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09707e7363c01437d67bd44feab983d5
https://pubmed.ncbi.nlm.nih.gov/16153604
https://pubmed.ncbi.nlm.nih.gov/16153604
Publikováno v:
Cancer research. 63(22)
Commercially available St. John's wort (Hypericum perforatum) preparations and some of their main constituents (hypericin, pseudohypericin, hyperforin, rutin, and quercetin) were examined for their potential to inhibit carcinogen activation by human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::279949cdcb0fd8bc852c1123efb4f074
https://pubmed.ncbi.nlm.nih.gov/14633740
https://pubmed.ncbi.nlm.nih.gov/14633740